Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
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Rimonabant
CAS:<p>Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.</p>Fórmula:C22H21Cl3N4OPureza:98% - 99.91%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:463.79CB1 antagonist 2
CAS:<p>CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.</p>Fórmula:C17H12Cl3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:380.666-Iodopravadoline
CAS:<p>6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.</p>Fórmula:C23H25IN2O3Pureza:99.29%Cor e Forma:Off-White SolidPeso molecular:504.36EHP-101
CAS:<p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>Fórmula:C28H35NO3Pureza:98.36%Cor e Forma:SolidPeso molecular:433.58Anandamide
CAS:<p>Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also</p>Fórmula:C22H37NO2Pureza:95.037% - 99.22%Cor e Forma:Light Yellow OilPeso molecular:347.53Rimonabant hydrochloride
CAS:<p>Rimonabant hydrochloride (SR 141716A) 是中心大麻素受体 1 的高效选择性反向激动剂， Ki 值为1.8 nM。它也能够抑制分枝杆菌膜蛋白3。</p>Fórmula:C22H22Cl4N4OPureza:98.24% - 99.5%Cor e Forma:Off-White To White Crystalline PowderPeso molecular:500.25Pregnenolone
CAS:<p>Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.</p>Fórmula:C21H32O2Pureza:99.5% - >99.99%Cor e Forma:SolidPeso molecular:316.48JHU 75528
CAS:<p>JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.</p>Fórmula:C23H21Cl2N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:470.35GPR55 agonist 4
<p>GPR55 agonist 4 (Compound 28), with an EC50 of 131 nM for hGPR55 and 1.41 nM for rGPR55, effectively induces β-arrestin recruitment to human GPR55 [1].</p>Fórmula:C19H16FN5O2Cor e Forma:SolidPeso molecular:365.36CB1R agonist 1
<p>CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.</p>Fórmula:C20H18F3N3O3SCor e Forma:SolidPeso molecular:437.435Hemopressin(rat)
CAS:<p>Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.</p>Fórmula:C53H77N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1088.27Vicasinabin
CAS:<p>Vicasinabin: potent CB2 agonist; researches chronic pain, atherosclerosis, bone mass, neuroinflammation.</p>Fórmula:C15H22N10OCor e Forma:SolidPeso molecular:358.41CB2R/FAAH modulator-3
CAS:<p>CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.</p>Fórmula:C22H31NO2Pureza:99.81%Cor e Forma:SoildPeso molecular:341.49NESS 0327
CAS:<p>NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.</p>Fórmula:C24H23Cl3N4OPureza:99.78%Cor e Forma:SolidPeso molecular:489.82(R)-Zevaquenabant
<p>(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.</p>Cor e Forma:Odour SolidRVD-Hpα
CAS:<p>N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>Fórmula:C65H105N19O17Pureza:98%Cor e Forma:SolidPeso molecular:1424.66Hemopressin (human, mouse)
CAS:<p>Endogenous peptide, inhibits ep24.15/24.16/ACE with Ki of 27.76/3.43/1.87 μM. Lowers blood pressure, CB1 inverse agonist, reduces pain in vivo.</p>Fórmula:C50H79N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1054.26N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide
CAS:<p>N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide: binds CB1 (Ki=365 nM), activates PPARα (EC50=698 nM), reduces rat food intake, no FAAH inhibition.</p>Fórmula:C27H45NO3Cor e Forma:SolidPeso molecular:431.661CB2R/FAAH modulator-1
CAS:<p>CB2R/FAAH modulator-1: agonizes CB2R, inhibits FAAH (IC50=4 μM), alters cytokine production; used in inflammation research. Ki: CB2R=14.8 nM, CB1R=241.3 nM.</p>Fórmula:C24H27NO2Pureza:99.77%Cor e Forma:SoildPeso molecular:361.48VIP36
<p>VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.</p>Fórmula:C27H35FN6O4Cor e Forma:SolidPeso molecular:526.603
