Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
TRPV1/CB2 agonist 1
<p>TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.</p>Cor e Forma:Odour SolidHemopressin(rat)
CAS:<p>Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.</p>Fórmula:C53H77N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1088.27Hemopressin(human, mouse) TFA
CAS:<p>Hemopressin TFA: nonapeptide from hemoglobin, oral CB1 inverse agonist, eases inflammatory pain.</p>Fórmula:C52H80F3N13O14Pureza:98%Cor e Forma:SolidPeso molecular:1168.27CB2R/FAAH modulator-2
CAS:<p>CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.</p>Fórmula:C24H33NO2Pureza:99.15%Cor e Forma:SoildPeso molecular:367.52Δ8-THC-C8
CAS:<p>Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.</p>Fórmula:C24H36O2Cor e Forma:SolidPeso molecular:356.54NESS 0327
CAS:<p>NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.</p>Fórmula:C24H23Cl3N4OPureza:99.78%Cor e Forma:SolidPeso molecular:489.82CB2R/FAAH modulator-3
CAS:<p>CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.</p>Fórmula:C22H31NO2Pureza:99.81%Cor e Forma:SoildPeso molecular:341.49APP-FUBINACA
CAS:<p>APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.</p>Fórmula:C24H21FN4O2Cor e Forma:SolidPeso molecular:416.45Drinabant
CAS:<p>Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.</p>Fórmula:C23H20Cl2F2N2O2SPureza:99.8%Cor e Forma:SolidPeso molecular:497.38(R)-Zevaquenabant
<p>(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.</p>Cor e Forma:Odour SolidCB1R agonist 1
<p>CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.</p>Fórmula:C20H18F3N3O3SCor e Forma:SolidPeso molecular:437.435Zevaquenabant
CAS:<p>Zevaquenabant (S-MRI-1867): oral CB1/iNOS antagonist combatting obesity-induced CKD.</p>Fórmula:C25H21ClF3N5O2SCor e Forma:SolidPeso molecular:547.98RVD-Hpα
CAS:<p>N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>Fórmula:C65H105N19O17Pureza:98%Cor e Forma:SolidPeso molecular:1424.66Vicasinabin
CAS:<p>Vicasinabin: potent CB2 agonist; researches chronic pain, atherosclerosis, bone mass, neuroinflammation.</p>Fórmula:C15H22N10OCor e Forma:SolidPeso molecular:358.41CB2R probe 1
CAS:<p>CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of</p>Fórmula:C36H42N4O4Cor e Forma:SolidPeso molecular:594.74Tocrifluor T1117
CAS:<p>Fluorescent form of AM 251, CB1 receptor antagonist</p>Fórmula:C56H53Cl2N7O5Pureza:98%Cor e Forma:SolidPeso molecular:974.97Hemopressin (human, mouse)
CAS:<p>Endogenous peptide, inhibits ep24.15/24.16/ACE with Ki of 27.76/3.43/1.87 μM. Lowers blood pressure, CB1 inverse agonist, reduces pain in vivo.</p>Fórmula:C50H79N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1054.26GFB-024
<p>GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.</p>Cor e Forma:LiquidPeso molecular:145.5kDaCB1R antagonist 2
<p>CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.</p>Fórmula:C24H26N4OCor e Forma:SolidPeso molecular:386.49δ8-THC acetate
CAS:<p>Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.</p>Fórmula:C23H32O3Cor e Forma:SolidPeso molecular:356.5
