Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
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CAS:<p>biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide</p>Fórmula:C36H60N4O5SPureza:98%Cor e Forma:SolidPeso molecular:660.95KLS-13019
CAS:<p>KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).</p>Fórmula:C22H29NO3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:355.47OMDM-6
CAS:<p>OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.</p>Fórmula:C28H42N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:454.64N-Arachidonyldopamine
CAS:<p>N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1</p>Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.63CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36AM6545
CAS:<p>AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.</p>Fórmula:C26H23Cl2N5O3SPureza:97.03%Cor e Forma:SolidPeso molecular:556.46Arvanil
CAS:<p>Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.</p>Fórmula:C28H41NO3Pureza:99.49%Cor e Forma:SolidPeso molecular:439.63MJ 15
CAS:<p>MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.</p>Fórmula:C23H17Cl3N4OPureza:99.63%Cor e Forma:SolidPeso molecular:471.77AZD1940
CAS:<p>AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.</p>Fórmula:C20H29F2N3O2SPureza:98.68%Cor e Forma:SolidPeso molecular:413.52JTE-907
CAS:<p>JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。</p>Fórmula:C24H26N2O6Pureza:99.93%Cor e Forma:SolidPeso molecular:438.47CB1 agonist 1
CAS:<p>CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.</p>Fórmula:C24H24N2O5SPureza:98.56%Cor e Forma:SolidPeso molecular:452.52SCH-336
CAS:<p>SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.</p>Fórmula:C23H25NO8S3Pureza:95.01%Cor e Forma:SolidPeso molecular:539.64Olorinab
CAS:<p>Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.</p>Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:SolidPeso molecular:357.41SR144528
CAS:<p>SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).</p>Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05PSB-CB5
CAS:<p>PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Fórmula:C20H17ClN2O2SPureza:99.26%Cor e Forma:SolidPeso molecular:384.88CB2R PAM
CAS:<p>CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.</p>Fórmula:C21H24BrFN2O2Pureza:99.09%Cor e Forma:SolidPeso molecular:435.33AM-1235
CAS:<p>AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.</p>Fórmula:C24H21FN2O3Pureza:97.77%Cor e Forma:SolidPeso molecular:404.43CB1R antagonist 1
CAS:<p>CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.</p>Fórmula:C18H23F3N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:404.45Nonabine
CAS:<p>Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.</p>Fórmula:C25H33NO2Pureza:99.46% - 99.95%Cor e Forma:SolidPeso molecular:379.54CAY10508
CAS:<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Fórmula:C21H14Br2N2O2Cor e Forma:SolidPeso molecular:486.2
