Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 215 produtos de "Receptor de Canabinóides"
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ML-191
CAS:ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.Fórmula:C24H25N3O3Pureza:99.58%Cor e Forma:SolidPeso molecular:403.47ML-184
CAS:ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM.Fórmula:C25H34N4O3SPureza:99.45%Cor e Forma:SolidPeso molecular:470.63ARN272
CAS:ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Fórmula:C27H20N4O2Pureza:98.23%Cor e Forma:SolidPeso molecular:432.47JD-5037
CAS:JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.Fórmula:C27H27Cl2N5O3SPureza:99.54% - 99.84%Cor e Forma:SolidPeso molecular:572.51GW842166X
CAS:<p>GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.</p>Fórmula:C18H17Cl2F3N4O2Pureza:99.47%Cor e Forma:SolidPeso molecular:449.25Olivetol
CAS:Olivetol, found in lichens, is an organic antioxidant and THC synthesis precursor.Fórmula:C11H16O2Pureza:99.98%Cor e Forma:(Melting Point 102-106°F) (Ntp 1992)Peso molecular:180.24Org 27569
CAS:<p>Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and</p>Fórmula:C24H28ClN3OPureza:>99.99% - ≥95%Cor e Forma:SolidPeso molecular:409.95N-Oleoyl glycine
CAS:N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated AktFórmula:C20H37NO3Pureza:97.43%Cor e Forma:SolidPeso molecular:339.51yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Cor e Forma:Pale Yellow PowderPeso molecular:258.27RVD-Hpα acetate(1193362-76-3 free base)
RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.Fórmula:C67H109N19O19Pureza:99.87%Cor e Forma:SolidPeso molecular:1484.71Bay 59-3074
CAS:<p>Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM).</p>Fórmula:C18H13F6NO4SPureza:97.68% - 99.69%Cor e Forma:SolidPeso molecular:453.36AM1241
CAS:<p>AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.</p>Fórmula:C22H22IN3O3Pureza:98.937% - 99.1%Cor e Forma:SolidPeso molecular:503.33CB1 antagonist 4
CAS:TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.Fórmula:C30H25Cl2F3N4OSPureza:98.97%Cor e Forma:SolidPeso molecular:617.51AM281
CAS:AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.Fórmula:C21H19Cl2IN4O2Pureza:98.6% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:557.21Hemopressin (rat) acetate(568588-77-2 free base)
<p>Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.</p>Fórmula:C5H81N13O14Pureza:99.37%Cor e Forma:SolidPeso molecular:1148.31CB1-IN-1
CAS:CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.Fórmula:C33H31Cl2F3N6O3S2Pureza:99.08% - 99.76%Cor e Forma:SolidPeso molecular:751.67Otenabant hydrochloride
CAS:<p>Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).</p>Fórmula:C25H26Cl3N7OPureza:99.79% - ≥95%Cor e Forma:SolidPeso molecular:546.88A-836339
CAS:A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.Fórmula:C16H26N2O2SPureza:99.94%Cor e Forma:SolidPeso molecular:310.45Voacamine
CAS:<p>Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.</p>Fórmula:C43H52N4O5Pureza:98.54% - 99.82%Cor e Forma:SolidPeso molecular:704.9LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Fórmula:C22H27ClN6OPureza:98.45% - 99.51%Cor e Forma:SolidPeso molecular:426.94
