Receptor GNRH
Os receptores do hormônio liberador de gonadotropina (GnRH) são GPCRs que se ligam ao GnRH, um hormônio responsável por regular a liberação do hormônio luteinizante (LH) e do hormônio folículo-estimulante (FSH) pela glândula pituitária. Esses receptores são cruciais para a função reprodutiva e são alvo em terapias para condições como câncer de próstata, endometriose e infertilidade. Agonistas e antagonistas dos receptores de GnRH também são usados em tecnologias de reprodução assistida. Na CymitQuimica, oferecemos uma gama abrangente de moduladores de receptores de GnRH de alta qualidade para apoiar sua pesquisa em saúde reprodutiva, endocrinologia e terapia hormonal.
Foram encontrados 84 produtos de "Receptor GNRH"
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Linzagolix
CAS:Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by KisseiFórmula:C22H15F3N2O7SPureza:99.33%Cor e Forma:SolidPeso molecular:508.42Goserelin acetate
CAS:Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.Fórmula:C61H88N18O16Pureza:99.77% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:1329.46Cetrorelix Acetate
CAS:Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.Fórmula:C70H92ClN17O14·xC2H4O2Pureza:97.96%Cor e Forma:SolidPeso molecular:1491.11Fertirelin acetate
CAS:Fertirelin acetate is a gonadotropin-releasing hormone (GnRH) agonist.Fórmula:C55H74N16O13Cor e Forma:SolidPeso molecular:1167.29Argtide
CAS:Argtide is an luteinizing hormone releasing hormone (LHRH) antagonist.Fórmula:C80H104ClN21O14Cor e Forma:SolidPeso molecular:1619.27NBI-42902
CAS:NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49EA-230
CAS:Ea-230 is an immunomodulator that may be used in the treatment of renal failure.Fórmula:C15H27N5O6Cor e Forma:SolidPeso molecular:373.4BAY 1214784
CAS:BAY 1214784 is a selective and orally active human GnRH-R antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49%.Fórmula:C29H26ClF4N3O5S2Pureza:100% - 99.77%Cor e Forma:SolidPeso molecular:672.11Opigolix
CAS:Opigolix is a Gonadotropin-releasing hormone receptor antagonist.Fórmula:C25H19F3N4O5SPureza:98.60% - 98.97%Cor e Forma:SolidPeso molecular:544.5BAY-784
CAS:BAY-784 is a potent GnRH receptor antagonist with nanomolar activity in human and rat receptors, widely used in endocrine and reproductive research.Fórmula:C29H26ClF4N3O5S2Pureza:99.22% - 99.75%Cor e Forma:SolidPeso molecular:672.115α-Pregnane-3α,20α-diol
CAS:5α-Pregnane-3α,20α-diol, an active metabolite of progesterone, is synthesized through intermediates 5α-pregnane-20α-ol-3-one and 5α-pregnane-3α-ol-20-one fromFórmula:C21H36O2Cor e Forma:SolidPeso molecular:320.51T 98475
CAS:gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally activeFórmula:C37H37F2N3O4SPureza:98%Cor e Forma:SolidPeso molecular:657.77BAY-298
CAS:BAY-298: oral LH-R antagonist; IC50: 96nM (hLH), 23nM (rLH), 78nM (cLH); first to lower sex hormones in vivo.Fórmula:C27H21ClFN3O2Pureza:98%Cor e Forma:SolidPeso molecular:473.93DCOIT
CAS:DCOIT, an isothiazolinone derivative, stimulates the synthesis of follicle-stimulating hormone and luteinizing hormone in the brain by activating the gonadotropin-releasing hormone receptor (GnRHR). Additionally, it interferes with G protein-coupled receptors, MAPK, and Ca 2+ signaling pathways [1].Fórmula:C11H17Cl2NOSCor e Forma:SolidPeso molecular:282.22[D-Ala6]-LH-RH
CAS:[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].Fórmula:C56H77N17O13Cor e Forma:SolidPeso molecular:1196.32Abarelix acetate
CAS:Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.Fórmula:C72H95ClN14O14·xC2H4O2Cor e Forma:SolidPeso molecular:1476.14BAY-899
CAS:BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Fórmula:C25H19F2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:459.45(R)-BAY-899
(R)-BAY-899: R-isomer, selective LH-R antagonist, effective on hLH (IC50: 185 nM) and rLH (IC50: 46 nM), orally active.Fórmula:C25H19F2N5O2Cor e Forma:SolidPeso molecular:459.45GnRH-R antagonist 1
CAS:Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.Fórmula:C31H28F5N7O6SPureza:98%Cor e Forma:SolidPeso molecular:721.65GnRH antagonist 2
CAS:GnRH antagonist 2 is a GnRH receptor antagonist, useful for studying endocrine diseases.Fórmula:C28H27F2N9O5Pureza:98.08%Cor e Forma:SolidPeso molecular:607.57
