DHFR
A diidrofolato redutase (DHFR) é uma enzima que desempenha um papel crucial no ciclo do folato, essencial para a síntese, reparo e metilação do DNA. Inibidores de DHFR são amplamente utilizados como agentes quimioterápicos no tratamento do câncer e de doenças autoimunes devido à sua capacidade de inibir a proliferação celular. Na CymitQuimica, oferecemos uma variedade de inibidores de DHFR para apoiar sua pesquisa em terapia do câncer, imunologia e biologia molecular.
Foram encontrados 34 produtos de "DHFR"
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Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
Key enzyme in folate metabolism.Cor e Forma:Lyophilized PowderPeso molecular:25.6 kDa (predicted)Dihydrofolate reductase Protein, Human, Recombinant (His)
Key enzyme in folate metabolism.Cor e Forma:Lyophilized PowderPeso molecular:25.5 kDa (predicted)Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
<p>Key enzyme in folate metabolism.</p>Cor e Forma:Lyophilized PowderPeso molecular:22.0 kDa (predicted)DHFR-IN-5
CAS:<p>DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.</p>Fórmula:C18H24N4O4Cor e Forma:SolidPeso molecular:360.41Clociguanil
CAS:Clociguanil has antimalarial activity.Fórmula:C12H15Cl2N5OCor e Forma:SolidPeso molecular:316.19Piritrexim
CAS:Piritrexim (BW 301U) is an orally available fat-soluble dihydrofolate reductase inhibitor with pulmonary toxicity used in the study of uroepithelial carcinomaFórmula:C17H19N5O2Pureza:98.50% - >99.99%Cor e Forma:SolidPeso molecular:325.3710-Deazaaminopterin
CAS:<p>10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.</p>Fórmula:C20H21N7O5Cor e Forma:SolidPeso molecular:439.42(Rac)-Managlinat dialanetil
CAS:<p>Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.</p>Fórmula:C21H33N4O6PSPureza:98.52%Cor e Forma:SolidPeso molecular:500.55Talotrexin ammonium
CAS:<p>Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.</p>Fórmula:C27H30N10O6Pureza:97.49%Cor e Forma:SolidPeso molecular:590.594′-DTMP
CAS:<p>4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.</p>Fórmula:C13H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:276.29Methotrexate-γ-aspartate
CAS:Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.Fórmula:C24H27N9O8Pureza:98%Cor e Forma:SolidPeso molecular:569.53Phototrexate
CAS:Phototrexate, a photochromic Methotrexate analog, is a UVA-activated, reversible DHFR inhibitor with antifolate properties (IC50: 6 nM cis vs. 34 μM trans).Fórmula:C20H19N7O5Cor e Forma:SolidPeso molecular:437.41Brodimoprim
CAS:<p>Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).</p>Fórmula:C13H15BrN4O2Pureza:98% - 98.33%Cor e Forma:SolidPeso molecular:339.19DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Fórmula:C18H21N5O2SPureza:99.41%Cor e Forma:SolidPeso molecular:371.46
