Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 708 produtos de "Síntese de DNA/RNA"
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Carboxy-pyridostatin
CAS:<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Fórmula:C35H34N10O7Cor e Forma:SolidPeso molecular:706.715'-O-DMT-ibu-dC
CAS:<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Fórmula:C34H37N3O7Cor e Forma:SolidPeso molecular:599.67ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Fórmula:C19H15Cl2N3O2S2Pureza:98.1%Cor e Forma:SolidPeso molecular:452.3816,16-dimethyl Prostaglandin A1
CAS:<p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>Fórmula:C22H36O4Cor e Forma:SolidPeso molecular:364.526Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Fórmula:C31H24O15Cor e Forma:SolidPeso molecular:636.51PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Cor e Forma:Odour Liquid5'-O-DMT-Bz-rC
CAS:<p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C37H35N3O8Cor e Forma:SolidPeso molecular:649.695-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Fórmula:C10H15N3Na3O14P3Cor e Forma:SolidPeso molecular:563.13M7G(3'-OMe-5')pppA(2'-OMe)
<p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>Fórmula:C23H33N10O17P3Cor e Forma:SolidPeso molecular:814.49GS-443902 trisodium
CAS:<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Fórmula:C12H16N5O13P3·xNaCor e Forma:SolidPOLRMT-IN-1
<p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>Cor e Forma:Odour SolidCytidine 5'-diphosphate trisodium salt
CAS:<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Fórmula:C9H15N3Na3O11P2Pureza:99.55%Cor e Forma:White Crystalline PowderPeso molecular:472.15Nitrosofolic acid
CAS:<p>Nitrosofolic acid is a folic acid derivaive.</p>Fórmula:C19H18N8O7Cor e Forma:SolidPeso molecular:470.40Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Fórmula:C37H35F3N10O9Pureza:98%Cor e Forma:SolidPeso molecular:820.73Xanthosine-5'-Triphosphate
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Fórmula:C10H15N4O15P3Cor e Forma:SolidPeso molecular:524.164RNA splicing modulator 1
CAS:<p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>Fórmula:C19H20N6OSCor e Forma:SolidPeso molecular:380.47Lorutengitide
CAS:<p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>Fórmula:C30H50N8O12Cor e Forma:SolidPeso molecular:714.764CSN5-IN-2
<p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>Cor e Forma:Odour SolidPseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Fórmula:C27H23ClF2N4O2Cor e Forma:SolidPeso molecular:508.9472'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
<p>2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.</p>Fórmula:C10H11FLi4N5O12P3Cor e Forma:SolidPeso molecular:532.9
