Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 708 produtos de "Síntese de DNA/RNA"
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Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Fórmula:C9H1415N2NaO15P3Cor e Forma:SolidPeso molecular:517.04HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:<p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>Fórmula:C57H62N8O10SCor e Forma:SolidPeso molecular:1051.212'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
<p>2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.</p>Fórmula:C10H11FLi4N5O12P3Cor e Forma:SolidPeso molecular:532.95'-O-DMT-rI
CAS:<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C31H30N4O7Cor e Forma:SolidPeso molecular:570.595'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Cor e Forma:SolidPeso molecular:687.743'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Fórmula:C9H12N2Na3O14P3Cor e Forma:SoildPeso molecular:534.08TS-002266
CAS:<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Fórmula:C31H32Cl2N6O5Pureza:98.18%Cor e Forma:SoildPeso molecular:639.535'-O-DMT-N4-Bz-2'-F-dC
CAS:<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Fórmula:C37H34FN3O7Cor e Forma:SolidPeso molecular:651.68Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Fórmula:C42H50N7O7PCor e Forma:SolidPeso molecular:795.878TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Fórmula:C17H21N3Pureza:99.99%Cor e Forma:SolidPeso molecular:267.37DNA Gyrase-IN-15
<p>DNA Gyrase-IN-15 (Compound 11) is an antibacterial agent that inhibits both DHPS and DNA gyrase, with IC50 values of 1.73 and 0.07 µM, respectively. It shows antimicrobial activity against Enterococcus faecium (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Additionally, DNA Gyrase-IN-15 exhibits antibiofilm activity against Enterococcus faecium.</p>Fórmula:C31H26N4O4S2Cor e Forma:SolidPeso molecular:582.693cis-Lomibuvir
CAS:<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Fórmula:C25H35NO4SCor e Forma:SolidPeso molecular:445.618-NH2-ATP
CAS:<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Fórmula:C10H17N6O13P3Cor e Forma:SolidPeso molecular:522.205-Methylcytidine 5′-triphosphate
CAS:<p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>Fórmula:C10H18N3O14P3Cor e Forma:SolidPeso molecular:497.18T2AA
CAS:<p>T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-</p>Fórmula:C15H15I2NO3Pureza:99.53%Cor e Forma:SolidPeso molecular:511.092'-MOE-G(iBu)-3'-phosphoramidite
CAS:<p>2'-MOE-G(iBu)-3'-phosphoramidite is a Nucleoside Phosphoramidite;Nucleoside Derivative - 2'-Modified nucleoside;.</p>Fórmula:C47H60N7O10PCor e Forma:SolidPeso molecular:913.995-Formylindole-CE phosphoramidite
CAS:<p>Nucleoside Derivatives - Indole nucleosides; Nucleoside Phosphoramidites</p>Fórmula:C44H50N3O7PCor e Forma:SolidPeso molecular:763.86DMTr-TNA-5MeU-amidite
CAS:<p>DMTr-TNA-5MeU-amidite is a Nucleoside Phosphoramidite.</p>Fórmula:C39H47N4O8PCor e Forma:SolidPeso molecular:730.79DHPS-IN-1
CAS:<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Fórmula:C17H13BrClN3O2Cor e Forma:SolidPeso molecular:406.66DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites</p>Fórmula:C45H54N7O9PCor e Forma:SolidPeso molecular:867.93
