Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 710 produtos de "Síntese de DNA/RNA"
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1,4-Anthraquinone
CAS:<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Fórmula:C14H8O2Pureza:95.96% - 97.01%Cor e Forma:Orange Brown SolidPeso molecular:208.21TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Fórmula:C13H13Cl3N4Cor e Forma:SolidPeso molecular:331.63SCR7 pyrazine
CAS:<p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>Fórmula:C18H12N4OSPureza:98.72% - 99.85%Cor e Forma:SolidPeso molecular:332.38Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Cor e Forma:SolidPeso molecular:286.2CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Fórmula:C27H29Cl2N7O2SCor e Forma:SolidPeso molecular:586.54Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Cor e Forma:SolidPeso molecular:749.94Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Fórmula:C38H46N5NaO7S2Pureza:98%Cor e Forma:SolidPeso molecular:771.92Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Fórmula:C31H37Cl5N8O5Cor e Forma:SolidPeso molecular:778.941-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Fórmula:C14H8O3Pureza:99.56%Cor e Forma:Orange Red Needles Red-Orange To Fine Yellow CrystalsPeso molecular:224.21Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SCor e Forma:SolidPeso molecular:515.56Idarubicin hydrochloride
CAS:<p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>Fórmula:C26H27NO9·HClPureza:98.91% - 99.96%Cor e Forma:SolidPeso molecular:533.95BRD32048
CAS:<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Fórmula:C16H22N6OPureza:99.87%Cor e Forma:SolidPeso molecular:314.39RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Cor e Forma:SolidPeso molecular:361.61Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Fórmula:C22H23N7OPureza:98.68% - 99.64%Cor e Forma:SolidPeso molecular:401.46TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Cor e Forma:SolidPeso molecular:541.18HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Fórmula:C17H13NO2Pureza:99.96%Cor e Forma:SolidPeso molecular:263.29BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:360.41TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Cor e Forma:SolidPeso molecular:269.13Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Fórmula:C5H5N5·HClPureza:98.86%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:171.59Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Cor e Forma:SolidPeso molecular:784.87
