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Síntese de DNA/RNA

Síntese de DNA/RNA

Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.

Foram encontrados 711 produtos de "Síntese de DNA/RNA"

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  • UIAA-II-232
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    UIAA-II-232

    CAS:
    <p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>
    Fórmula:C20H24FN5O3
    Cor e Forma:Solid
    Peso molecular:401.43

    Ref: TM-T61950

  • RHI002-Me
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    RHI002-Me

    CAS:
    <p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>
    Fórmula:C18H19N3O2S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:373.49

    Ref: TM-T28535

  • Antitumor agent-84
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    Antitumor agent-84

    <p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>
    Fórmula:C24H31N7
    Cor e Forma:Solid
    Peso molecular:417.55

    Ref: TM-T72571

  • Homocarbonyltopsentin
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    Homocarbonyltopsentin

    CAS:
    <p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>
    Fórmula:C21H14N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:370.36

    Ref: TM-T13723

  • TDRL-X80
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    TDRL-X80

    CAS:
    <p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>
    Fórmula:C23H15ClN2O6
    Cor e Forma:Solid
    Peso molecular:450.83

    Ref: TM-T62730

  • Phelorphan
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    Phelorphan

    CAS:
    <p>Phelorphan is an inhibitor of enkephalinase.</p>
    Fórmula:C20H22N2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.46

    Ref: TM-T25941

  • 3'-Deoxyuridine-5'-triphosphate
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    3'-Deoxyuridine-5'-triphosphate

    CAS:
    <p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I &amp; II, with a Ki of 2.0 µM.</p>
    Fórmula:C9H15N2O14P3
    Cor e Forma:Solid
    Peso molecular:468.14

    Ref: TM-T35657

  • Triaziquone
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    Triaziquone

    CAS:
    <p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>
    Fórmula:C12H13N3O2
    Cor e Forma:Solid
    Peso molecular:231.25

    Ref: TM-T34927

  • Beaucage reagent
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    Beaucage reagent

    CAS:
    Beaucage reagent, which is found to be effective in causing DNA cleavage.
    Fórmula:C7H4O3S2
    Pureza:98.50%
    Cor e Forma:White To Off-White Powder
    Peso molecular:200.23

    Ref: TM-T14522

  • HIPP
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    HIPP

    CAS:
    <p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>
    Fórmula:C9H9NO3
    Cor e Forma:Solid
    Peso molecular:179.17

    Ref: TM-T24140

  • BMH-22
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    BMH-22

    CAS:
    <p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Fórmula:C16H17N3
    Cor e Forma:Solid
    Peso molecular:251.33

    Ref: TM-T23802

  • JFN05510
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    JFN05510

    CAS:
    <p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>
    Fórmula:C50H68N7O9PSi
    Cor e Forma:Solid
    Peso molecular:970.18

    Ref: TM-T71943

  • Phen-DC3
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    Phen-DC3

    CAS:
    <p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>
    Fórmula:C34H26N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:550.61

    Ref: TM-T13817

  • MLAF50
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    MLAF50

    CAS:
    <p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>
    Fórmula:C15H12I2O4
    Cor e Forma:Solid
    Peso molecular:510.06

    Ref: TM-T70719

  • NPD9948
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    NPD9948

    CAS:
    <p>NPD9948 is a competitive inhibitor of MTH1.</p>
    Fórmula:C13H14N6
    Cor e Forma:Solid
    Peso molecular:254.29

    Ref: TM-T28194

  • HIV-1 inhibitor-43
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    HIV-1 inhibitor-43

    CAS:
    <p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), &lt;0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>
    Fórmula:C24H21ClN2O4S
    Cor e Forma:Solid
    Peso molecular:468.95

    Ref: TM-T63018

  • HBV-IN-4
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    HBV-IN-4

    CAS:
    <p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>
    Fórmula:C24H19ClFN5O3
    Cor e Forma:Solid
    Peso molecular:479.89

    Ref: TM-T36747

  • Cylindrospermopsin
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    Cylindrospermopsin

    CAS:
    <p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>
    Fórmula:C15H21N5O7S
    Cor e Forma:Solid
    Peso molecular:415.42

    Ref: TM-T35770

  • GW8510
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    GW8510

    CAS:
    <p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>
    Fórmula:C21H15N5O3S2
    Pureza:99.32%
    Cor e Forma:Solid
    Peso molecular:449.51

    Ref: TM-T24125

  • BAY-707
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    BAY-707

    CAS:
    <p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>
    Fórmula:C15H20N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:288.34

    Ref: TM-T14509