Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 710 produtos de "Síntese de DNA/RNA"
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Didox
CAS:<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Fórmula:C7H7NO4Pureza:99.83%Cor e Forma:SolidPeso molecular:169.13(S)-crizotinib
CAS:<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Fórmula:C21H22Cl2FN5OPureza:98.52% - 99.47%Cor e Forma:SolidPeso molecular:450.34COH29
CAS:<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Cor e Forma:SolidPeso molecular:420.44Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Fórmula:C9H18NOPureza:98.35%Cor e Forma:Orange Crystals Or PowderPeso molecular:156.25Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Fórmula:C9H10FIN2O5Pureza:99.71% - 99.88%Cor e Forma:Less Crystals Colourless CrystalsPeso molecular:372.09TH287 hydrochloride
CAS:<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Fórmula:C11H11Cl3N4Pureza:>99.99%Cor e Forma:SolidPeso molecular:305.59Neobavaisoflavone
CAS:<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Fórmula:C20H18O4Pureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:322.35PolQi2
CAS:<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Fórmula:C21H16ClN5O3SPureza:99.19%Cor e Forma:SolidPeso molecular:453.92'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Fórmula:C13H19N5O5Pureza:99.35%Cor e Forma:SolidPeso molecular:325.325-Bromouridine
CAS:<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Fórmula:C9H11BrN2O6Pureza:99.89%Cor e Forma:White PowderPeso molecular:323.1GSK4418959
CAS:<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Fórmula:C31H30F4N4O5SPureza:99.141%Cor e Forma:SoildPeso molecular:646.65DHX9-IN-8
CAS:<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Fórmula:C18H16N2O3S2Cor e Forma:SolidPeso molecular:372.46VVD-214
CAS:<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Fórmula:C20H21F2N3O4SPureza:99.24%Cor e Forma:SoildPeso molecular:437.46Metribuzin
CAS:<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Fórmula:C8H14N4OSPureza:99.07%Cor e Forma:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29Locked nucleic acid 1
CAS:<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Fórmula:C32H32N2O8Pureza:98%Cor e Forma:SolidPeso molecular:572.61E-982
CAS:<p>E-982 is derived from the reference compound.</p>Fórmula:C25H31NO6SPureza:98%Cor e Forma:SolidPeso molecular:473.582'-Azido-2'-deoxyuridine
CAS:<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Fórmula:C9H11N5O5Pureza:98%Cor e Forma:SolidPeso molecular:269.21RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Fórmula:C19H17N3Cor e Forma:SolidPeso molecular:287.363,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Fórmula:C7H10BrNO2Pureza:98.49%Cor e Forma:Light Beige Crystalline PowderPeso molecular:220.06Halofuginone
CAS:<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Fórmula:C16H17BrClN3O3Pureza:99.53%Cor e Forma:Off-White SolidPeso molecular:414.68E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46BMVC
CAS:<p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>Fórmula:C28H25I2N3Cor e Forma:SolidPeso molecular:657.33BzDANP
CAS:<p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>Fórmula:C18H24N6Cor e Forma:SolidPeso molecular:324.42Zelpolib
CAS:<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Fórmula:C22H21N3O5S2Pureza:98.79%Cor e Forma:SolidPeso molecular:471.55SEC inhibitor KL-2
CAS:<p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>Fórmula:C17H13ClFNO3Pureza:99.86%Cor e Forma:SolidPeso molecular:333.74AM-TS23
CAS:AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.Fórmula:C17H12N2O3S3Pureza:98%Cor e Forma:SolidPeso molecular:388.48ML366
CAS:<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Fórmula:C17H19N3O4Pureza:98%Cor e Forma:SolidPeso molecular:329.35Meturedepa
CAS:<p>Meturedepa is an antineoplastic agent.</p>Fórmula:C11H22N3O3PPureza:98%Cor e Forma:SolidPeso molecular:275.28SPC-839
CAS:<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Fórmula:C18H14N4O3SCor e Forma:SolidPeso molecular:366.39MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55Thiarabine
CAS:<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Fórmula:C9H13N3O4SPureza:98%Cor e Forma:SolidPeso molecular:259.288-Azido-ADP disodium
CAS:<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Fórmula:C10H13N8NaO10P2Cor e Forma:SolidPeso molecular:490.1972-Keto-D-galactose
CAS:<p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>Fórmula:C6H10O6Pureza:98%Cor e Forma:SolidPeso molecular:178.14S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Fórmula:C12H16N2O2S2Cor e Forma:SolidPeso molecular:284.4Codon readthrough inducer 1
CAS:Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.Fórmula:C15H11N3O5Pureza:98%Cor e Forma:SolidPeso molecular:313.26MS0017509
CAS:<p>MS0017509 is a DNA damage repair inhibitor.</p>Fórmula:C11H10N4Pureza:98%Cor e Forma:SolidPeso molecular:198.22CTP Synthetase-IN-1
CAS:CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.Fórmula:C20H19F3N6O3S2Pureza:98.11% - 99.18%Cor e Forma:SolidPeso molecular:512.53DHX9-IN-1
CAS:<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Fórmula:C21H21F2N5O3SCor e Forma:SolidPeso molecular:461.49JNJ-9676
CAS:<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Fórmula:C28H21F2N5O2Pureza:99.83%Cor e Forma:SoildPeso molecular:497.5Direct Black 38 free acid
CAS:<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Fórmula:C34H27N9O7S2Pureza:98%Cor e Forma:SolidPeso molecular:737.77Crisnatol
CAS:<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Fórmula:C23H23NO2Cor e Forma:SolidPeso molecular:345.43DENV-IN-4
CAS:<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Fórmula:C28H32N4O4SiCor e Forma:SolidPeso molecular:516.66CGP 53353
CAS:<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Fórmula:C20H13F2N3O2Pureza:98.11%Cor e Forma:SolidPeso molecular:365.33IDD388
CAS:IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Fórmula:C16H12BrClFNO4Pureza:99.56%Cor e Forma:SolidPeso molecular:416.635,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Cor e Forma:SolidPeso molecular:438.44Werner syndrome RecQ helicase-IN-4
CAS:<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.65CM03
CAS:<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Fórmula:C34H44N6O6Pureza:98.65%Cor e Forma:SolidPeso molecular:632.75Laromustine
CAS:<p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>Fórmula:C6H14ClN3O5S2Pureza:≥98%Cor e Forma:SolidPeso molecular:307.78DDD100097
CAS:<p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>Fórmula:C22H30Cl2F2N4O2SPureza:98.89%Cor e Forma:SolidPeso molecular:523.47Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Fórmula:C24H31N7Cor e Forma:SolidPeso molecular:417.55
