Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 708 produtos de "Síntese de DNA/RNA"
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RNA polymerase II-IN-1
CAS:<p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>Fórmula:C38H53N11O12SPureza:98%Cor e Forma:SolidPeso molecular:887.96DHX9-IN-6
CAS:<p>DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.</p>Fórmula:C23H18ClFN4O4S2Pureza:99.71%Cor e Forma:SolidPeso molecular:533DHX9-IN-4
CAS:<p>DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.</p>Fórmula:C21H22ClN5O4S2Pureza:98.12%Cor e Forma:SolidPeso molecular:508.01DDD85646
CAS:<p>DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.</p>Fórmula:C21H24Cl2N6O2SPureza:97.8% - 99.76%Cor e Forma:SolidPeso molecular:495.43RAD51-IN-4
CAS:<p>RAD51-IN-4, a potent RAD51 inhibitor, may be useful in researching mitochondrial defect-related conditions.</p>Fórmula:C31H34FN5O5S2Cor e Forma:SolidPeso molecular:639.76Balapiravir hydrochloride
CAS:<p>Balapiravir HCl, an NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Fórmula:C21H31ClN6O8Cor e Forma:SolidPeso molecular:530.96G4/HDAC-IN-1
<p>G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.</p>Fórmula:C36H49ClFN7O4Cor e Forma:SolidPeso molecular:698.2712R-LOX-IN-1
CAS:<p>12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX.</p>Fórmula:C15H11NO2Cor e Forma:SolidPeso molecular:237.25Galidesivir hydrochloride
CAS:<p>Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.</p>Fórmula:C11H16ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:301.738-NH2-ATP tetrasodium
CAS:<p>8-NH2-ATP tetrasodium, an inactive ATP variant, originates from 8-NH2-Ado tetrasodium, which triggers the apoptosis-associated cleavage of poly (ADP-ribose) polymerase [1] [2].</p>Fórmula:C10H13N6Na4O13P3Cor e Forma:SolidPeso molecular:610.12KY386
CAS:<p>KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM.</p>Fórmula:C21H19N5O2SCor e Forma:SolidPeso molecular:405.47WRN inhibitor 5
CAS:<p>WRN Inhibitor 5 (Example 157), a cyclic vinyl sulfone-based compound, serves as an inhibitor of Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Fórmula:C23H20N2O6SCor e Forma:SolidPeso molecular:452.48Emzadirib
CAS:<p>Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.</p>Fórmula:C27H40N4O6S2Pureza:99.79% - 99.9%Cor e Forma:SolidPeso molecular:580.76MC-VC-PAB-Cyclohexanediamine-Thailanstatin A
CAS:<p>MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a spliceostatin analog and a drug-linker conjugate for antibody-drug conjugates (ADC), comprising the cytotoxic</p>Fórmula:C63H91N9O16Pureza:98%Cor e Forma:SolidPeso molecular:1230.45WRN inhibitor 4
CAS:<p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Fórmula:C16H14N2O5SCor e Forma:SolidPeso molecular:346.36NVS-SM2
CAS:<p>NVS-SM2 boosts SMN2 splicing, enhances exon 7 inclusion, and raises SMN protein levels orally.</p>Fórmula:C23H30N6OCor e Forma:SolidPeso molecular:406.52Thymectacin
CAS:<p>Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.</p>Fórmula:C21H25BrN3O9PPureza:97.05% - 99.49%Cor e Forma:SolidPeso molecular:574.32LNA-Adenosine
CAS:<p>LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.</p>Fórmula:C11H13N5O4Pureza:99.15%Cor e Forma:SolidPeso molecular:279.25SMN-C3
CAS:<p>SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).</p>Fórmula:C24H28N6OPureza:99.01% - 99.05%Cor e Forma:SolidPeso molecular:416.52DHX9-IN-2
CAS:<p>DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.</p>Fórmula:C18H16ClN3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:421.92
