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Síntese de DNA/RNA

Síntese de DNA/RNA

Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.

Foram encontrados 794 produtos de "Síntese de DNA/RNA"

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  • RNA splicing modulator 2

    CAS:
    RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .
    Fórmula:C20H21N5OS
    Cor e Forma:Solid
    Peso molecular:379.48
  • 7-TFA-ap-7-Deaza-ddG

    CAS:
    Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.
    Fórmula:C16H16F3N5O4
    Cor e Forma:Solid
    Peso molecular:399.33
  • 5-Iminodaunorubicin

    CAS:
    5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.
    Fórmula:C27H30N2O9
    Cor e Forma:Solid
    Peso molecular:526.54
  • Pyrindamycin A

    CAS:
    Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.
    Fórmula:C26H26ClN3O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:543.95
  • ddGTP trisodium


    ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.
    Fórmula:C10H13N5Na3O12P3
    Cor e Forma:Solid
    Peso molecular:557.13
  • RNA splicing modulator 3

    CAS:
    RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].
    Fórmula:C19H20N6OS
    Cor e Forma:Solid
    Peso molecular:380.47
  • Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Fórmula:C23H20F2N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:426.41
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Fórmula:C27H23ClF2N4O2
    Cor e Forma:Solid
    Peso molecular:508.947
  • HDAC-IN-85


    HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.
    Fórmula:C24H27FN4O5
    Cor e Forma:Solid
    Peso molecular:470.49
  • Ac-rC Phosphoramidite

    CAS:
    Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
    Fórmula:C47H64N5O9PSi
    Pureza:98.29%
    Cor e Forma:Solid
    Peso molecular:902.1
  • EFdA-TP

    CAS:
    EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.
    Fórmula:C12H15FN5O12P3
    Cor e Forma:Solid
    Peso molecular:533.195
  • ONX 0801 trisodium

    CAS:
    ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.
    Fórmula:C32H30N5Na3O10
    Cor e Forma:Solid
    Peso molecular:713.58
  • PAT-LM1


    PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.
    Cor e Forma:Odour Liquid
  • 5-Methylcytidine 5′-triphosphate trisodium


    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Cor e Forma:Solid
    Peso molecular:563.13
  • Nusinersen

    CAS:
    Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.
    Pureza:98.62%
    Cor e Forma:Solid
  • Carbazole

    CAS:
    <p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>
    Fórmula:C12H9N
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:167.211
  • Antipain

    CAS:
    Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.
    Fórmula:C27H44N10O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:604.713
  • 8-NH2-ATP

    CAS:
    8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.
    Fórmula:C10H17N6O13P3
    Cor e Forma:Solid
    Peso molecular:522.20
  • Remdesivir nucleoside monophosphate

    CAS:
    Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.
    Fórmula:C12H14N5O7P
    Cor e Forma:Solid
    Peso molecular:371.24
  • DMT-5Me-dC(Bz)-CE Phosphoramidite

    CAS:
    DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.
    Fórmula:C47H54N5O8P
    Cor e Forma:Solid
    Peso molecular:847.93