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HIV Protease

HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 447 produtos de "HIV Protease"

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  • Lopinavir

    CAS:
    <p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>
    Fórmula:C37H48N4O5
    Pureza:98% - 99.62%
    Cor e Forma:White Crystalline Solid
    Peso molecular:628.8
  • Didanosine

    CAS:
    <p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>
    Fórmula:C10H12N4O3
    Pureza:99.64%
    Cor e Forma:White Crystalline Powder
    Peso molecular:236.23
  • Rilpivirine

    CAS:
    <p>Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment</p>
    Fórmula:C22H18N6
    Pureza:97.22% - 98.83%
    Cor e Forma:Solid
    Peso molecular:366.42
  • Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Fórmula:C16H10ClF3N2O
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:338.71
  • 2,4-Dihydroxypyridine

    CAS:
    <p>2,4-Dihydroxypyridine: a pyridine derivative, chelates metals, assesses ion levels, measures enzymatic reactions, and quantifies biomolecules.</p>
    Fórmula:C5H5NO2
    Pureza:97.79%
    Cor e Forma:White To Yellow-Beige Crystals Or
    Peso molecular:111.1
  • Dimercaprol

    CAS:
    <p>Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-</p>
    Fórmula:C3H8OS2
    Pureza:98.91% - 99.64%
    Cor e Forma:Viscous Oily Liquid
    Peso molecular:124.22
  • Raltegravir potassium

    CAS:
    <p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>
    Fórmula:C20H20FN6O5·K
    Pureza:98% - 99.55%
    Cor e Forma:Off-White Solid
    Peso molecular:482.51
  • NBD-557

    CAS:
    <p>NBD-557 is a potentially HIV-1 inhibitor.</p>
    Fórmula:C17H24BrN3O2
    Pureza:99.52%
    Cor e Forma:Solid
    Peso molecular:382.3
  • Raltegravir

    CAS:
    <p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>
    Fórmula:C20H21FN6O5
    Pureza:99.86% - >99.99%
    Cor e Forma:Solid
    Peso molecular:444.42
  • IMB-301

    CAS:
    <p>IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.</p>
    Fórmula:C19H17Cl2FN2O
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:379.26
  • Lamivudine 13C,15N2

    CAS:
    <p>Lamivudine 13C,15N2, a BCH-189 impurity, blocks HIV/HBV reverse transcriptase as an NRTI.</p>
    Fórmula:C8H9N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:246.22
  • Nelfinavir

    CAS:
    <p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>
    Fórmula:C32H45N3O4S
    Pureza:98.16% - 99.5%
    Cor e Forma:White To Off-White Crystalline Powder
    Peso molecular:567.78
  • Elipovimab

    CAS:
    <p>Elipovimab, a potent and broadly neutralizing antibody against HIV-1, targets and eliminates HIV-infected cells [1].</p>
    Cor e Forma:Liquid
  • Semzuvolimab

    CAS:
    <p>Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4).</p>
    Cor e Forma:Liquid
  • Suvizumab

    CAS:
    <p>Suvizumab (KD-247) is a neutralizing anti-HIV-1 antibody with IC50 values of 0.1-1.0 µg/mL; it lowers viral load and prevents infection.</p>
    Cor e Forma:Liquid
  • Antiviral agent 55

    CAS:
    <p>Antiviralagent 55 (Compound 95) is an inhibitor of human immunodeficiency viruses 1 and 2 (HIV1 and HIV2), demonstrating antiviral activity.</p>
    Fórmula:C21H20N2O4
    Cor e Forma:Solid
    Peso molecular:364.39
  • Benzalphthalide

    CAS:
    <p>Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.</p>
    Fórmula:C15H10O2
    Pureza:99.94%
    Cor e Forma:Pale Yellow To Yellow Crystalline Powder
    Peso molecular:222.24
  • Zinlirvimab

    CAS:
    <p>Zinlirvimab is a humanized IgG1-λ2 monoclonal antibody that neutralizes HIV by targeting the HIV-1 gp120 envelope glycoprotein, specifically the IIIB gp120 V3</p>
    Cor e Forma:Liquid
  • Nipamovir

    CAS:
    <p>Nipamovir is a nitroimidazole prodrug that exhibits antiviral activity comparable to SAMT-247 and NS-1040 in cellular assays and a human ex vivo model of HIV infection, with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively [1].</p>
    Fórmula:C14H15N5O4S
    Cor e Forma:Solid
    Peso molecular:349.37
  • Antiviral agent 9


    <p>Antiviral agent 9: EC50 0.006 nM vs HIV-1, 300x more selective than TAF.</p>
    Fórmula:C38H50N7O8P
    Cor e Forma:Solid
    Peso molecular:763.82
  • APOBEC3G-IN-1

    CAS:
    <p>APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.</p>
    Fórmula:C15H11NO3
    Pureza:96.54%
    Cor e Forma:Solid
    Peso molecular:253.25
  • HIV-IN-6

    CAS:
    <p>HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.</p>
    Fórmula:C20H16N4O3S
    Pureza:97.12%
    Cor e Forma:Solid
    Peso molecular:392.43
  • HIV-1 inhibitor-49


    <p>HIV-1 inhibitor-49, an oral HEPT analog, has strong pharmacokinetics, potent reverse transcriptase inhibition (IC50=30nM), and is safe in mice.</p>
    Fórmula:C21H18F2N2O3S
    Cor e Forma:Solid
    Peso molecular:416.44
  • MK-2048

    CAS:
    <p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>
    Fórmula:C21H21ClFN5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:461.87
  • HIV-1 inhibitor-22

    CAS:
    <p>HIV-1 inhibitor-22 effectively blocks HIV-1 RT (IC50=3.63 μM) with low cytotoxicity (CC50 &gt; 227 μM).</p>
    Fórmula:C30H26N6O3S
    Cor e Forma:Solid
    Peso molecular:550.63
  • HIV-1 integrase inhibitor 4

    CAS:
    <p>HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).</p>
    Fórmula:C24H20F2N4O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:514.5
  • HIV-1 inhibitor-29

    CAS:
    <p>HIV-1 inhibitor-29: Blocks HIV-1 IIIB (EC50: 2.18μM), resists F227L/V106A (EC50: 0.974μM), low toxicity (CC50: 211μM), for AIDS research.</p>
    Fórmula:C30H36N6O5
    Cor e Forma:Solid
    Peso molecular:560.64
  • D77

    CAS:
    <p>D77 is anti-HIV-1 inhibitor. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).</p>
    Fórmula:C28H22BrNO7S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:596.45
  • HIV-1 inhibitor-34

    CAS:
    <p>HIV-1 inhibitor-34 (5q): potent, selective; EC50: 6.4 nM; MT-4 CC50: 16 μM; useful in AIDS research.</p>
    Fórmula:C26H27N7O
    Cor e Forma:Solid
    Peso molecular:453.54
  • HIV-IN-4

    CAS:
    <p>HIV-IN-4 (Compound 12) is a potent HIV inhibitor that exhibits promising anti-HIV activities [1].</p>
    Fórmula:C14H18N2O3
    Cor e Forma:Solid
    Peso molecular:262.3
  • HIV-1 inhibitor-16

    CAS:
    <p>HIV-1 inhibitor-16: potent with EC50 1.3 nM for wild-type; inhibits K103N, E138K, Y181C, L100I strains; good solubility; stable; low CYP impact; non-toxic.</p>
    Fórmula:C23H16F2N6
    Cor e Forma:Solid
    Peso molecular:414.41
  • HIV-1 inhibitor-57

    CAS:
    <p>HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50</p>
    Fórmula:C25H24FN5O3S
    Cor e Forma:Solid
    Peso molecular:493.55
  • SARS-CoV-IN-3

    CAS:
    <p>SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.</p>
    Fórmula:C25H28ClFeN3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:477.81
  • Mesoxalic acid

    CAS:
    <p>Mesoxalic acid is a dicarboxylic acid and a ketonic acid which blocks RT translocation.</p>
    Fórmula:C3H2O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:118.04
  • SAMT-247

    CAS:
    <p>SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.</p>
    Fórmula:C12H14N2O3S
    Cor e Forma:Solid
    Peso molecular:266.32
  • TMC310911

    CAS:
    <p>TMC310911 is an oral HIV-1 protease inhibitor with an EC50 of 2.2-14.2 nM, effective against various HIV-1 strains.</p>
    Fórmula:C38H53N5O7S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:755.99
  • Reverse transcriptase-IN-3


    <p>Reverse transcriptase-IN-3, a pyrimidine carboxamide, inhibits HIV-1 including mutant strains.</p>
    Fórmula:C28H31N7O4S
    Cor e Forma:Solid
    Peso molecular:561.66
  • DQBS

    CAS:
    <p>DQBS is an HIV-1 Nef function antagonist.</p>
    Fórmula:C22H17ClN4O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:468.91
  • HIV-1 integrase inhibitor 7

    CAS:
    <p>HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).</p>
    Fórmula:C30H26O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:642.52
  • β-L-D4A

    CAS:
    <p>beta-L-D4A inhibits HIV-1 reverse transcriptase, stopping DNA synthesis.</p>
    Fórmula:C10H11N5O2
    Pureza:99.45%
    Cor e Forma:Solid
    Peso molecular:233.23
  • MK-4965

    CAS:
    <p>MK-4965 is a new type of non-nucleoside reverse transcriptase inhibitor with antiviral activity.</p>
    Fórmula:C20H13Cl2N5O2
    Cor e Forma:Solid
    Peso molecular:426.26
  • gp120-IN-1

    CAS:
    <p>gp120-IN-1 (4e) is a potent HIV-1 inhibitor, IC50 2.2 μM, CC50 100.90 μM, and blocks HIV entry.</p>
    Fórmula:C15H18N2O4S
    Cor e Forma:Solid
    Peso molecular:322.38
  • HIV-1 inhibitor-25

    CAS:
    <p>Compound R-12a is a potent HIV-1 reverse transcriptase inhibitor (IC50: 0.1061 nM), with low cytotoxicity and effective against multiple mutants.</p>
    Fórmula:C26H19N5O2
    Cor e Forma:Solid
    Peso molecular:433.46
  • LEDGIN6

    CAS:
    <p>HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.</p>
    Fórmula:C21H20ClNO2
    Cor e Forma:Solid
    Peso molecular:353.84
  • NIT

    CAS:
    <p>NIT is an HIV-1 protease inhibitor.</p>
    Fórmula:C15H7N3O4S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:357.36
  • HIV-1 inhibitor-36

    CAS:
    <p>HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].</p>
    Fórmula:C14H14Cl2N2O2S
    Cor e Forma:Solid
    Peso molecular:345.24
  • HIV-1 inhibitor-24

    CAS:
    <p>HIV-1 inhibitor-24 (S-12a) blocks HIV reverse transcription effectively (IC50: 9.5 nM), low toxicity, well-tolerated in mice, good heart safety.</p>
    Fórmula:C26H19N5O2
    Cor e Forma:Solid
    Peso molecular:433.46
  • DPC-681

    CAS:
    <p>DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).</p>
    Fórmula:C35H48FN5O5S
    Cor e Forma:Solid
    Peso molecular:669.85
  • HIV-1 inhibitor-19

    CAS:
    <p>HIV-1 inhibitor-19 is a potent NNRTI targeting L100I, K103N, V106A/F227L mutants; EC50s: 7.3, 9.2, 21.0 nM respectively.</p>
    Fórmula:C24H22BClN2O5S
    Cor e Forma:Solid
    Peso molecular:496.77
  • HIV-1 inhibitor-15

    CAS:
    <p>HIV-1 inhibitor-15 (compound 9d): Potent, broad-spectrum, EC50=1.7-9 nM for various strains, good solubility/safety, oral use.</p>
    Fórmula:C24H20N6
    Cor e Forma:Solid
    Peso molecular:392.46
  • TX-1918

    CAS:
    <p>TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.</p>
    Fórmula:C14H12O3
    Cor e Forma:Solid
    Peso molecular:228.24
  • S 2720

    CAS:
    <p>S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.</p>
    Fórmula:C14H15ClN2O2S
    Cor e Forma:Solid
    Peso molecular:310.8
  • 1E7-03

    CAS:
    <p>1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).</p>
    Fórmula:C28H29N3O6
    Cor e Forma:Solid
    Peso molecular:503.55
  • DPC-961

    CAS:
    <p>DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Fórmula:C14H10ClF3N2O
    Cor e Forma:Solid
    Peso molecular:314.69
  • B07 hydrochloride

    CAS:
    <p>B07 hydrochloride is a CCR5 antagonist-based inhibitor of HIV-1 entry.</p>
    Fórmula:C29H38ClFN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:529.09
  • GCA-186

    CAS:
    <p>GCA-186 is an effective non-nucleoside HIV-1 reverse transcriptase inhibitor.</p>
    Fórmula:C19H26N2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:330.42
  • HIV-1 inhibitor-20

    CAS:
    <p>HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.</p>
    Fórmula:C19H11ClF3N3O2
    Cor e Forma:Solid
    Peso molecular:405.76
  • BMS-585248

    CAS:
    <p>BMS-585248 is a highly effective HIV-1 adhesion inhibitor that targets the viral envelope protein gp120.</p>
    Fórmula:C22H18FN7O3
    Cor e Forma:Solid
    Peso molecular:447.42
  • AIC-292

    CAS:
    <p>AIC-292 is a potent, tolerable reverse transcriptase inhibitor active against various HIV-1 strains, including NNRTI-resistant K103N, G190A, Y181C.</p>
    Fórmula:C19H12Cl2F2N4O2
    Cor e Forma:Solid
    Peso molecular:437.23
  • L 739594

    CAS:
    <p>L 739594 is an inhibitor of HIV-1 protease.</p>
    Fórmula:C31H47N3O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:557.72
  • HIV-1 inhibitor-28

    CAS:
    <p>HIV-1 inhibitor-28: potent, selective, EC50=58 nM, low MT-4 cell toxicity (CC50=38.6 μM), valuable in AIDS research.</p>
    Fórmula:C26H32N6O3S
    Cor e Forma:Solid
    Peso molecular:508.64
  • HIV-1 inhibitor-45

    CAS:
    <p>HIV-1 inhibitor-45 is a potent inhibitor of HIV-1 RNase H (IC50: 0.067 μM) and has antiviral effects.</p>
    Fórmula:C23H24N4O8S
    Cor e Forma:Solid
    Peso molecular:516.52
  • HIV-1 inhibitor-21

    CAS:
    <p>HIV-1 inhibitor-21 (compound 9b) blocks HIV-1 RT effectively (IC50: 0.55 μM), targeting wild-type and K103N strains, with low toxicity (CC50: 10.2 μM).</p>
    Fórmula:C28H24N6O2
    Cor e Forma:Solid
    Peso molecular:476.53
  • HI-236

    CAS:
    <p>HI-236 is used as a non-nucleoside HIV-1 reverse-transcriptase inhibitor.</p>
    Fórmula:C16H18BrN3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:396.3
  • Adenallene

    CAS:
    <p>Adenallene inhibits replication and cytopathic effects of HIV in vitro.</p>
    Fórmula:C9H9N5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:203.2
  • AQ 148

    CAS:
    <p>AQ 148 is a potent competitive inhibitor of HIV-1 PR.</p>
    Fórmula:C30H37N3O4
    Cor e Forma:Solid
    Peso molecular:503.63
  • HIV-1 integrase inhibitor 9

    CAS:
    <p>HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.</p>
    Fórmula:C18H12N2O10
    Cor e Forma:Solid
    Peso molecular:416.3
  • Reverse transcriptase-IN-4


    <p>Reverse transcriptase-IN-4: potent, selective NNRT inhibitor; EC50 = 0.053 μM for HIV-1, 0.26 μM for E138K mutant.</p>
    Fórmula:C17H21N5OS
    Cor e Forma:Solid
    Peso molecular:343.45
  • Rovafovir Etalafenamide

    CAS:
    <p>Rovafovir Etalafenamide is a prodrug of anti-HIV nucleoside phosphonate.</p>
    Fórmula:C21H24FN6O6P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:506.42
  • SARS-CoV-IN-2

    CAS:
    <p>SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor</p>
    Fórmula:C24H26ClFeN3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:463.78
  • HIV-1 inhibitor-23

    CAS:
    <p>HIV-1 inhibitor-23 suppresses HIV reverse transcriptase, effective on wild-type (EC50: 24.9 nM) and K103N mutant (EC50: 10.4 nM), with in vitro stability.</p>
    Fórmula:C30H26N6O4S
    Cor e Forma:Solid
    Peso molecular:566.63
  • R 82150

    CAS:
    <p>R 82150 is an antiviral and a member of the tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thione family.</p>
    Fórmula:C16H21N3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:287.42
  • DLC27-14

    CAS:
    <p>DLC27-14 is an HIV-1 Nef specific protein disorder catalyzer.</p>
    Fórmula:C25H25NO4
    Cor e Forma:Solid
    Peso molecular:403.47
  • HIV-1 inhibitor-32

    CAS:
    <p>HIV-1 inhibitor-32 is a potent inhibitor of HIV-1 that acts on wild-type HIV (IC50: 34 nM) and can be used in AIDS research.</p>
    Fórmula:C26H29N5O3S
    Cor e Forma:Solid
    Peso molecular:491.61
  • HIV-1 protease-IN-2

    CAS:
    <p>HIV-1 protease-IN-2: strong HIV-1 protease blocker, IC50 2.53 nM, fights DRV-sensitive/resistant HIV-1.</p>
    Fórmula:C27H34N4O7S
    Cor e Forma:Solid
    Peso molecular:558.65
  • HIV-1 inhibitor-46

    CAS:
    <p>HIV-1 inhibitor-46, compound 13d, is a potent non-nucleoside reverse transcriptase inhibitor with an EC50 of 1.425 μM, useful in AIDS research.</p>
    Fórmula:C24H21ClN4OS
    Cor e Forma:Solid
    Peso molecular:448.97
  • HIV-1 inhibitor-37

    CAS:
    <p>HIV-1 inhibitor-37, a potent HIV-1 suppressant, shows promise as a novel latent reactivator.</p>
    Fórmula:C14H11Cl3N4O
    Cor e Forma:Solid
    Peso molecular:357.62
  • Tenofovir maleate

    CAS:
    <p>Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B.</p>
    Fórmula:C13H18N5O8P
    Cor e Forma:Solid
    Peso molecular:403.28
  • Stampidine

    CAS:
    <p>Stampidine prevents HIV-1, effective against resistant strains at subnanomolar levels.</p>
    Fórmula:C20H23BrN3O8P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:544.29
  • HIV-1 inhibitor-30

    CAS:
    <p>HIV-1 inhibitor-30 (10i) targets RT enzyme, EC50=40nM, IC50=80nM. Effective against seven NNRTI-resistant HIV-1 strains.</p>
    Fórmula:C19H20ClN3O2
    Cor e Forma:Solid
    Peso molecular:357.83
  • Edelfosine

    CAS:
    <p>inhibits phosphatidylinositol phospholipase C</p>
    Fórmula:C27H58NO6P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:523.73
  • (+)-Dihydrocalanolide A

    CAS:
    <p>DHCal A (NSC 678323) is an oral nonnucleoside Reverse Transcriptase inhibitor for HIV research.</p>
    Fórmula:C22H28O5
    Cor e Forma:Solid
    Peso molecular:372.45
  • HIV-IN-5

    CAS:
    <p>HIV-IN-5 (5r) inhibits HIV-1 with 0.16 μM IC50, targeting NNIBP as a NNRTI.</p>
    Fórmula:C30H24N2O8S
    Cor e Forma:Solid
    Peso molecular:572.59
  • HIV-1 inhibitor-47

    CAS:
    <p>HIV-1 Inhibitor-47 blocks Vif-APOBEC3G interaction, has 14.33 μM IC50, and may yield antianxiety and antipsychotic derivatives.</p>
    Fórmula:C12H14N6
    Cor e Forma:Solid
    Peso molecular:242.28
  • L 870810

    CAS:
    <p>L 870810 is a small-molecule inhibitor of HIV-1 integrase with potent antiviral activity in cell culture and good pharmacokinetic properties.</p>
    Fórmula:C20H19FN4O4S
    Cor e Forma:Solid
    Peso molecular:430.45
  • HIV-1 protease-IN-5

    CAS:
    <p>HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.</p>
    Fórmula:C27H29F3N2O7S
    Cor e Forma:Solid
    Peso molecular:582.59
  • DPC-963

    CAS:
    <p>DPC-963 is a RNA-directed DNA polymerase inhibitor.</p>
    Fórmula:C14H9F5N2O
    Cor e Forma:Solid
    Peso molecular:316.23
  • Brecanavir

    CAS:
    <p>Brecanavir is a tyrosyl-based arylsulfonamide, high affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type 1.</p>
    Fórmula:C33H41N3O10S2
    Cor e Forma:Solid
    Peso molecular:703.82
  • ZINC04177596

    CAS:
    <p>ZINC04177596 is a novel Nef Protein Inhibitor with anti-HIV activity.</p>
    Fórmula:C22H16N6O4
    Cor e Forma:Solid
    Peso molecular:428.4
  • HIV-1 inhibitor-42

    CAS:
    <p>HIV-1 inhibitor-42 (5b) strongly blocks HIV-1 (IC50: 0.06μM) and its RT RNA/DNA polymerases (IC50: 0.518/0.072μM).</p>
    Fórmula:C22H20N2O5S
    Cor e Forma:Solid
    Peso molecular:424.47
  • EP39


    <p>EP39 is a potent HIV-1 inhibitor, stabilizing the SP1 domain's helix and blocking virus maturation.</p>
    Fórmula:C38H62N2O5
    Cor e Forma:Solid
    Peso molecular:626.91
  • SJ-3366

    CAS:
    <p>SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.</p>
    Fórmula:C21H24N2O3
    Cor e Forma:Solid
    Peso molecular:352.43
  • HIV-1 protease-IN-1

    CAS:
    <p>HIV-1 protease-IN-1, potent HIV inhibitor; IC50=90pM, fights B/C-HIV strains with EC50=89-13.59/8.23nM.</p>
    Fórmula:C25H35N3O6S
    Cor e Forma:Solid
    Peso molecular:505.63
  • VEC-5

    CAS:
    <p>VEC-5: an HIV-1 inhibitor, outperforms RN18 by better binding with Vif in studies.</p>
    Fórmula:C29H21NO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:447.48
  • HIV-1 inhibitor-38

    CAS:
    <p>HIV-1 inhibitor-38, or Compound 91, shows promise as a strong latency reversing agent against HIV-1.</p>
    Fórmula:C15H13Cl3N6
    Cor e Forma:Solid
    Peso molecular:383.66
  • A3N19

    CAS:
    <p>A3N19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase and is able to act on HIV-1 IIIB (EC50: 3.28 nM).</p>
    Fórmula:C31H31N9O2S
    Cor e Forma:Solid
    Peso molecular:593.7
  • DMJ-I-228

    CAS:
    <p>DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.</p>
    Fórmula:C19H19ClFN5O4
    Cor e Forma:Solid
    Peso molecular:435.84
  • gp120-IN-2

    CAS:
    <p>gp120-IN-2 is a potent HIV-1 inhibitor (IC50 = 7.5 μM) with low cytotoxicity (CC50 = 112.93 μM).</p>
    Fórmula:C15H18N2O5
    Cor e Forma:Solid
    Peso molecular:306.31
  • A 80987

    CAS:
    <p>A 80987 is an inhibitor of HIV-1 protease.</p>
    Fórmula:C37H43N5O6
    Cor e Forma:Solid
    Peso molecular:653.77
  • GW-695634

    CAS:
    <p>GW-695634, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Fórmula:C26H21Cl2N3O6S
    Cor e Forma:Solid
    Peso molecular:574.43