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HIV Protease

HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 447 produtos de "HIV Protease"

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  • Doravirine

    CAS:
    <p>Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.</p>
    Fórmula:C17H11ClF3N5O3
    Pureza:99.65% - 99.79%
    Cor e Forma:Solid
    Peso molecular:425.75
  • Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Fórmula:C16H10ClF3N2O
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:338.71
  • RN-18

    CAS:
    <p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>
    Fórmula:C20H16N2O4S
    Pureza:97.21% - 98.39%
    Cor e Forma:Solid
    Peso molecular:380.42
  • Filgotinib

    CAS:
    <p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>
    Fórmula:C21H23N5O3S
    Pureza:98.03% - ≥95%
    Cor e Forma:Solid
    Peso molecular:425.5
  • Raltegravir

    CAS:
    <p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>
    Fórmula:C20H21FN6O5
    Pureza:99.86% - >99.99%
    Cor e Forma:Solid
    Peso molecular:444.42
  • Filgotinib maleate

    CAS:
    <p>Filgotinib maleate, a selective oral JAK1 inhibitor, treats RA and Crohn's. IC50s: JAK1-10nM, JAK2-28nM, JAK3-810nM, TYK2-116nM.</p>
    Fórmula:C25H27N5O7S
    Cor e Forma:Solid
    Peso molecular:541.58
  • HIV-1 Inhibitor 18A

    CAS:
    <p>HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.</p>
    Fórmula:C14H11N5O2S
    Pureza:99.79%
    Cor e Forma:Solid
    Peso molecular:313.33
  • HIV-1 Nef-IN-1

    CAS:
    <p>HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).</p>
    Fórmula:C18H16O2
    Pureza:99.90%
    Cor e Forma:Solid
    Peso molecular:264.32
  • Indinavir sulfate

    CAS:
    <p>Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.</p>
    Fórmula:C36H49N5O8S
    Pureza:99.75% - >99.99%
    Cor e Forma:White Powder
    Peso molecular:711.87
  • Rolipram

    CAS:
    <p>Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.</p>
    Fórmula:C16H21NO3
    Pureza:99.22% - >99.99%
    Cor e Forma:Solid
    Peso molecular:275.34
  • Lamivudine 13C,15N2

    CAS:
    <p>Lamivudine 13C,15N2, a BCH-189 impurity, blocks HIV/HBV reverse transcriptase as an NRTI.</p>
    Fórmula:C8H9N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:246.22
  • Nelfinavir

    CAS:
    <p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>
    Fórmula:C32H45N3O4S
    Pureza:98.16% - 99.5%
    Cor e Forma:White To Off-White Crystalline Powder
    Peso molecular:567.78
  • Suvizumab

    CAS:
    <p>Suvizumab (KD-247) is a neutralizing anti-HIV-1 antibody with IC50 values of 0.1-1.0 µg/mL; it lowers viral load and prevents infection.</p>
    Cor e Forma:Liquid
  • Elipovimab

    CAS:
    <p>Elipovimab, a potent and broadly neutralizing antibody against HIV-1, targets and eliminates HIV-infected cells [1].</p>
    Cor e Forma:Liquid
  • Semzuvolimab

    CAS:
    <p>Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4).</p>
    Cor e Forma:Liquid
  • Benzalphthalide

    CAS:
    <p>Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.</p>
    Fórmula:C15H10O2
    Pureza:99.94%
    Cor e Forma:Pale Yellow To Yellow Crystalline Powder
    Peso molecular:222.24
  • Zinlirvimab

    CAS:
    <p>Zinlirvimab is a humanized IgG1-λ2 monoclonal antibody that neutralizes HIV by targeting the HIV-1 gp120 envelope glycoprotein, specifically the IIIB gp120 V3</p>
    Cor e Forma:Liquid
  • Nipamovir

    CAS:
    <p>Nipamovir is a nitroimidazole prodrug that exhibits antiviral activity comparable to SAMT-247 and NS-1040 in cellular assays and a human ex vivo model of HIV infection, with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively [1].</p>
    Fórmula:C14H15N5O4S
    Cor e Forma:Solid
    Peso molecular:349.37
  • Antiviral agent 55

    CAS:
    <p>Antiviralagent 55 (Compound 95) is an inhibitor of human immunodeficiency viruses 1 and 2 (HIV1 and HIV2), demonstrating antiviral activity.</p>
    Fórmula:C21H20N2O4
    Cor e Forma:Solid
    Peso molecular:364.39
  • AIC-292

    CAS:
    <p>AIC-292 is a potent, tolerable reverse transcriptase inhibitor active against various HIV-1 strains, including NNRTI-resistant K103N, G190A, Y181C.</p>
    Fórmula:C19H12Cl2F2N4O2
    Cor e Forma:Solid
    Peso molecular:437.23