HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 501 produtos de "HIV Protease"
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Atazanavir
CAS:Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.Fórmula:C38H52N6O7Pureza:98% - 99.95%Cor e Forma:Crystalline SolidPeso molecular:704.86Probenecid
CAS:Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.Fórmula:C13H19NO4SPureza:98.95% - 99.84%Cor e Forma:Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)Peso molecular:285.36TERT-IN-1
CAS:TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.Fórmula:C16H20ClN3SPureza:99.31%Cor e Forma:SoildPeso molecular:321.87NBD-556
CAS:NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.Fórmula:C17H24ClN3O2Pureza:99.79%Cor e Forma:SolidPeso molecular:337.84Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Fórmula:C34H63N5O9Pureza:96.74% - 99.94%Cor e Forma:SolidPeso molecular:685.89(S)-(+)-N-3-Benzylnirvanol
CAS:(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.Cost-effective and quality-assured.Fórmula:C18H18N2O2Pureza:98.90%Cor e Forma:SoildPeso molecular:294.353-Deazaadenosine hydrochloride
CAS:3-Deazaadenosine HCl blocks SAH hydrolase (Ki: 3.9 μM), with anti-inflammatory, anti-proliferative, and anti-HIV effects.Fórmula:C11H15ClN4O4Pureza:98.48%Cor e Forma:SolidPeso molecular:302.71Ref: TM-T10111
1mg119,00€5mg205,00€10mg354,00€25mg587,00€50mg822,00€100mg1.108,00€1mL*10mM (DMSO)141,00€(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.
Fórmula:C33H44N6O5Pureza:99.30%Cor e Forma:SolidPeso molecular:604.74Zalcitabine
CAS:Zalcitabine (ddC) is a nucleoside analog inhibiting HIV by blocking reverse transcriptase and halting viral DNA synthesis.Fórmula:C9H13N3O3Pureza:99.08% - ≥95%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:211.22Ritonavir
CAS:Ritonavir (ABT 538) inhibits HIV-1/2 proteases; serum proteins limit it but it enhances other HIV drugs by hindering P450 degradation.Fórmula:C37H48N6O5S2Pureza:99.38% - 99.96%Cor e Forma:White PowderPeso molecular:720.94Ref: TM-T1525
1g475,00€5mg34,00€10mg50,00€25mg74,00€50mg96,00€100mg138,00€200mg192,00€500mg321,00€1mL*10mM (DMSO)50,00€Salicylanilide
CAS:Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.
Fórmula:C13H11NO2Pureza:99.55%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:213.23Fostemsavir Tris
CAS:Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment.Fórmula:C29H37N8O11PPureza:99.45%Cor e Forma:SolidPeso molecular:704.62Ref: TM-T10570
1mg54,00€5mg114,00€10mg167,00€25mg268,00€50mg409,00€100mg580,00€1mL*10mM (DMSO)170,00€Dolutegravir intermediate-1
CAS:Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Fórmula:C13H17NO8Pureza:99.52%Cor e Forma:SolidPeso molecular:315.28Benfotiamine
CAS:Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.Fórmula:C19H23N4O6PSPureza:99.2% - 99.91%Cor e Forma:Shinning Black PowderPeso molecular:466.45Nevirapine
CAS:Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Fórmula:C15H14N4OPureza:99.58% - 99.59%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:266.3Ibalizumab
CAS:Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4
Pureza:SDS-PAGE:96.4%;SEC-HPLC:97.7%Cor e Forma:LiquidPeso molecular:147.3 kDaPF-3450074
CAS:PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Fórmula:C27H27N3O2Pureza:99.92%Cor e Forma:SolidPeso molecular:425.52GSK2838232
CAS:GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.
Fórmula:C48H73ClN2O6Pureza:97.97%Cor e Forma:SolidPeso molecular:809.56Elsulfavirine
CAS:Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.Fórmula:C24H17BrCl2FN3O5SPureza:99.66%Cor e Forma:SolidPeso molecular:629.28Ref: TM-T15210
1mg69,00€5mg147,00€10mg230,00€25mg462,00€50mg692,00€100mg973,00€1mL*10mM (DMSO)200,00€Atazanavir sulfate
CAS:Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.Fórmula:C38H52N6O7·H2SO4Pureza:99.31% - 99.40%Cor e Forma:SolidPeso molecular:802.93Ref: TM-T0100
5mg44,00€10mg58,00€25mg90,00€50mg114,00€100mg170,00€200mg250,00€500mg425,00€1mL*10mM (DMSO)50,00€Islatravir
CAS:Islatravir (MK-8591) is an effective anti-HIV-1 agent.Fórmula:C12H12FN5O3Pureza:98.77%Cor e Forma:SolidPeso molecular:293.25Ref: TM-T16098
1mg75,00€5mg161,00€10mg245,00€25mg430,00€50mg583,00€100mg783,00€200mg1.054,00€1mL*10mM (DMSO)172,00€Aureothin
CAS:Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).Fórmula:C22H23NO6Cor e Forma:SolidPeso molecular:397.42TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Fórmula:C65H124N34O15Pureza:98%Cor e Forma:SolidPeso molecular:1621.91ICeD-2
ICeD-2 triggers death in HIV-1 infected cells, requires HIV protease, inhibits DPP8/9, and stabilizes DPP9 in PBMCs.Fórmula:C20H29N3OCor e Forma:SolidPeso molecular:327.46L 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Fórmula:C38H47N5O5Cor e Forma:SolidPeso molecular:653.81Hinnuliquinone
CAS:Hinnuliquinone is an anti-HIV agent.Fórmula:C32H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:506.59Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Fórmula:C21H17F3N3NaO5Pureza:99.97%Cor e Forma:SolidPeso molecular:471.36HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Cor e Forma:Odour SolidSalvianan A
CAS:1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].Fórmula:C20H17NO2Cor e Forma:SolidPeso molecular:303.35HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFórmula:C26H24N6O2Cor e Forma:SolidPeso molecular:452.51Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Cor e Forma:Odour SolidRef: TM-L1100
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarScirpusin A
CAS:Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.Fórmula:C28H22O7Cor e Forma:SolidPeso molecular:470.47HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFórmula:C23H40O5Pureza:98%Cor e Forma:SolidPeso molecular:396.56HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Cor e Forma:Odour SolidKRL74
CAS:KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 μM and a Kd of 11.9 μM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 μM in virus-like particle (VLP) budding assays.Fórmula:C50H61ClN10O9Cor e Forma:SolidPeso molecular:981.53HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFórmula:C14H10N4O4SPureza:99.33%Cor e Forma:SolidPeso molecular:330.32BNM-III-170
CAS:BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.Fórmula:C25H26ClF7N6O6Cor e Forma:SolidPeso molecular:674.96MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Fórmula:C126H201N35O33SPureza:98%Cor e Forma:SolidPeso molecular:2766.22Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Fórmula:C67H124N34O14SPureza:98%Cor e Forma:SolidPeso molecular:1661.9912-Oxocalanolide A
12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.Fórmula:C22H24O5Cor e Forma:SolidPeso molecular:368.429NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Fórmula:C32H31N9O3SCor e Forma:SolidPeso molecular:621.71Kuguacin N
Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.Fórmula:C30H46O4Cor e Forma:SolidPeso molecular:470.694Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.43HIV gag peptide (197-205)
CAS:HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFórmula:C45H81N11O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1064.32HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Fórmula:C42H36ClF10N7O5S2Cor e Forma:SolidPeso molecular:1008.35Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Fórmula:C37H56F3N9O18Pureza:98%Cor e Forma:SolidPeso molecular:971.89HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Fórmula:C44H72N10O15Pureza:98%Cor e Forma:SolidPeso molecular:981.1SPD-756
CAS:SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C12H16N6O3Pureza:98%Cor e Forma:SolidPeso molecular:292.29GLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Fórmula:C102H194N40O20Pureza:98%Cor e Forma:SolidPeso molecular:2300.89
