HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 447 produtos de "HIV Protease"
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Probenecid
CAS:<p>Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.</p>Fórmula:C13H19NO4SPureza:98.95% - 99.84%Cor e Forma:Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)Peso molecular:285.36(S)-(+)-N-3-Benzylnirvanol
CAS:<p>(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.Cost-effective and quality-assured.</p>Fórmula:C18H18N2O2Pureza:98.90%Cor e Forma:SoildPeso molecular:294.35(Rac)-Telinavir
CAS:<p>N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.</p>Fórmula:C33H44N6O5Pureza:99.30%Cor e Forma:SolidPeso molecular:604.74Islatravir
CAS:<p>Islatravir (MK-8591) is an effective anti-HIV-1 agent.</p>Fórmula:C12H12FN5O3Pureza:98.77%Cor e Forma:SolidPeso molecular:293.25Salicylanilide
CAS:<p>Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.</p>Fórmula:C13H11NO2Pureza:99.55%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:213.23Dolutegravir intermediate-1
CAS:<p>Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.</p>Fórmula:C13H17NO8Pureza:99.52%Cor e Forma:SolidPeso molecular:315.28Ibalizumab
CAS:<p>Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4</p>Pureza:SDS-PAGE:96.4%;SEC-HPLC:97.7%Cor e Forma:LiquidPeso molecular:147.3 kDaGSK2838232
CAS:<p>GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.</p>Fórmula:C48H73ClN2O6Pureza:97.97%Cor e Forma:SolidPeso molecular:809.56Elsulfavirine
CAS:<p>Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.</p>Fórmula:C24H17BrCl2FN3O5SPureza:99.66%Cor e Forma:SolidPeso molecular:629.28Zalcitabine
CAS:<p>Zalcitabine (ddC) is a nucleoside analog inhibiting HIV by blocking reverse transcriptase and halting viral DNA synthesis.</p>Fórmula:C9H13N3O3Pureza:99.08% - ≥95%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:211.223-Deazaadenosine hydrochloride
CAS:<p>3-Deazaadenosine HCl blocks SAH hydrolase (Ki: 3.9 μM), with anti-inflammatory, anti-proliferative, and anti-HIV effects.</p>Fórmula:C11H15ClN4O4Pureza:98.48%Cor e Forma:SolidPeso molecular:302.71Nevirapine
CAS:<p>Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C15H14N4OPureza:99.58% - 99.59%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:266.3Fostemsavir Tris
CAS:<p>Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment.</p>Fórmula:C29H37N8O11PPureza:99.45%Cor e Forma:SolidPeso molecular:704.62BRD-6929
CAS:<p>BRD-6929, a brain-targeted HDAC1/2 inhibitor (IC50 1/8 nM), enhances gnidimacrin's anti-HIV effect, useful in mood behavior studies.</p>Fórmula:C19H17N3O2SPureza:98.01% - 99.05%Cor e Forma:SolidPeso molecular:351.42Pepstatin
CAS:<p>Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.</p>Fórmula:C34H63N5O9Pureza:96.74% - 99.94%Cor e Forma:SolidPeso molecular:685.89Benfotiamine
CAS:<p>Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.</p>Fórmula:C19H23N4O6PSPureza:99.2% - 99.91%Cor e Forma:Shinning Black PowderPeso molecular:466.45Atazanavir
CAS:<p>Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.</p>Fórmula:C38H52N6O7Pureza:98% - 99.95%Cor e Forma:Crystalline SolidPeso molecular:704.86Ritonavir
CAS:<p>Ritonavir (ABT 538) inhibits HIV-1/2 proteases; serum proteins limit it but it enhances other HIV drugs by hindering P450 degradation.</p>Fórmula:C37H48N6O5S2Pureza:99.38% - 99.96%Cor e Forma:White PowderPeso molecular:720.94Tenofovir diphosphate TEA
CAS:<p>Tenofovir diphosphate TEA (TFV-DP TEA) is an ATP-competitive DNA polymerase inhibitor that inhibits HIV-1 reverse transcriptase that\has anti-HIV/HBV potential.</p>Fórmula:C9H16N5O10P3·C6H15NPureza:93.45% - 98.51%Cor e Forma:SolidPeso molecular:548.36Hck-IN-1
CAS:<p>Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.</p>Fórmula:C16H11ClN6O3SPureza:99.07%Cor e Forma:SolidPeso molecular:402.81Atazanavir sulfate
CAS:<p>Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.</p>Fórmula:C38H52N6O7·H2SO4Pureza:99.31% - 99.40%Cor e Forma:SolidPeso molecular:802.93TERT-IN-1
CAS:<p>TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.</p>Fórmula:C16H20ClN3SPureza:99.31%Cor e Forma:SoildPeso molecular:321.87NBD-556
CAS:<p>NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.</p>Fórmula:C17H24ClN3O2Pureza:99.79%Cor e Forma:SolidPeso molecular:337.84PF-3450074
CAS:<p>PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.</p>Fórmula:C27H27N3O2Pureza:99.92%Cor e Forma:SolidPeso molecular:425.52L 754394
CAS:<p>L 754394 is an effective and specific inhibitor of the HIV-1 protease.</p>Fórmula:C38H47N5O5Cor e Forma:SolidPeso molecular:653.81HIV p17 Gag (77-85)
CAS:<p>Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.</p>Fórmula:C44H72N10O15Pureza:98%Cor e Forma:SolidPeso molecular:981.1Bictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Cor e Forma:SolidPeso molecular:471.36Globotriaosylceramides (porcine)
CAS:<p>Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.</p>Fórmula:C60H113NO18Cor e Forma:SolidPeso molecular:1136.553HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Cor e Forma:Odour SolidHIV-1 inhibitor-81
<p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>Fórmula:C32H44N2O8SCor e Forma:SolidPeso molecular:616.77HIV-1 protease-IN-10
<p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>Fórmula:C23H40O5Pureza:98%Cor e Forma:SolidPeso molecular:396.56Protease Inhibitor Library
<p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>Cor e Forma:Odour SolidScirpusin A
CAS:<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Fórmula:C28H22O7Cor e Forma:SolidPeso molecular:470.47HIV gag peptide (197-205)
CAS:<p>HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI</p>Fórmula:C45H81N11O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1064.32Peptide T TFA
CAS:<p>Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.</p>Fórmula:C37H56F3N9O18Pureza:98%Cor e Forma:SolidPeso molecular:971.89HIV-1 inhibitor-11
<p>HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.</p>Fórmula:C42H36ClF10N7O5S2Cor e Forma:SolidPeso molecular:1008.35Kuguacin N
<p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>Fórmula:C30H46O4Cor e Forma:SolidPeso molecular:470.694MPG, HIV related
CAS:<p>MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.</p>Fórmula:C126H201N35O33SPureza:98%Cor e Forma:SolidPeso molecular:2766.22NF279
CAS:<p>P2X1 antagonist</p>Fórmula:C49H36N6Na6O23S6Pureza:98%Cor e Forma:SolidPeso molecular:1407.17VIR-165
<p>VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.</p>Fórmula:C109H158N22O25S2Pureza:98%Cor e Forma:SolidPeso molecular:2240.7Delavirdine
CAS:<p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>Fórmula:C22H28N6O3SCor e Forma:SolidPeso molecular:456.56NNRT-IN-6
<p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>Fórmula:C32H31N9O3SCor e Forma:SolidPeso molecular:621.71Peptide T
CAS:<p>Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.</p>Fórmula:C35H55N9O16Pureza:98%Cor e Forma:SolidPeso molecular:857.86Cys-TAT(47-57)
CAS:<p>Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.</p>Fórmula:C67H124N34O14SPureza:98%Cor e Forma:SolidPeso molecular:1661.99MB-66
<p>MB-66 (MAPP-66) is a fully human IgG1 antibody targeting HSV and HIV. It is a monoclonal antibody membrane intended for vaginal application. The isotype control for MB-66 can be referred to as HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour LiquidSPD-756
CAS:<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C12H16N6O3Pureza:98%Cor e Forma:SolidPeso molecular:292.29HIV-1 inhibitor-59
<p>HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.</p>Fórmula:C28H28FN5O3SCor e Forma:SolidPeso molecular:533.62Clavirolide L
<p>Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 without</p>Fórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.43HIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Fórmula:C14H10N4O4SPureza:99.33%Cor e Forma:SolidPeso molecular:330.32Hinnuliquinone
CAS:<p>Hinnuliquinone is an anti-HIV agent.</p>Fórmula:C32H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:506.59
