
HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 447 produtos de "HIV Protease"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
TX-1918
CAS:<p>TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.</p>Fórmula:C14H12O3Cor e Forma:SolidPeso molecular:228.24S 2720
CAS:<p>S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.</p>Fórmula:C14H15ClN2O2SCor e Forma:SolidPeso molecular:310.81E7-03
CAS:<p>1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).</p>Fórmula:C28H29N3O6Cor e Forma:SolidPeso molecular:503.55DPC-961
CAS:<p>DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C14H10ClF3N2OCor e Forma:SolidPeso molecular:314.69B07 hydrochloride
CAS:<p>B07 hydrochloride is a CCR5 antagonist-based inhibitor of HIV-1 entry.</p>Fórmula:C29H38ClFN4O2Pureza:98%Cor e Forma:SolidPeso molecular:529.09GCA-186
CAS:<p>GCA-186 is an effective non-nucleoside HIV-1 reverse transcriptase inhibitor.</p>Fórmula:C19H26N2O3Pureza:98%Cor e Forma:SolidPeso molecular:330.42HIV-1 inhibitor-20
CAS:<p>HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.</p>Fórmula:C19H11ClF3N3O2Cor e Forma:SolidPeso molecular:405.76BMS-585248
CAS:<p>BMS-585248 is a highly effective HIV-1 adhesion inhibitor that targets the viral envelope protein gp120.</p>Fórmula:C22H18FN7O3Cor e Forma:SolidPeso molecular:447.42AIC-292
CAS:<p>AIC-292 is a potent, tolerable reverse transcriptase inhibitor active against various HIV-1 strains, including NNRTI-resistant K103N, G190A, Y181C.</p>Fórmula:C19H12Cl2F2N4O2Cor e Forma:SolidPeso molecular:437.23L 739594
CAS:<p>L 739594 is an inhibitor of HIV-1 protease.</p>Fórmula:C31H47N3O6Pureza:98%Cor e Forma:SolidPeso molecular:557.72HIV-1 inhibitor-28
CAS:<p>HIV-1 inhibitor-28: potent, selective, EC50=58 nM, low MT-4 cell toxicity (CC50=38.6 μM), valuable in AIDS research.</p>Fórmula:C26H32N6O3SCor e Forma:SolidPeso molecular:508.64HIV-1 inhibitor-45
CAS:<p>HIV-1 inhibitor-45 is a potent inhibitor of HIV-1 RNase H (IC50: 0.067 μM) and has antiviral effects.</p>Fórmula:C23H24N4O8SCor e Forma:SolidPeso molecular:516.52HIV-1 inhibitor-21
CAS:<p>HIV-1 inhibitor-21 (compound 9b) blocks HIV-1 RT effectively (IC50: 0.55 μM), targeting wild-type and K103N strains, with low toxicity (CC50: 10.2 μM).</p>Fórmula:C28H24N6O2Cor e Forma:SolidPeso molecular:476.53HI-236
CAS:<p>HI-236 is used as a non-nucleoside HIV-1 reverse-transcriptase inhibitor.</p>Fórmula:C16H18BrN3O2SPureza:98%Cor e Forma:SolidPeso molecular:396.3Adenallene
CAS:<p>Adenallene inhibits replication and cytopathic effects of HIV in vitro.</p>Fórmula:C9H9N5OPureza:98%Cor e Forma:SolidPeso molecular:203.2AQ 148
CAS:<p>AQ 148 is a potent competitive inhibitor of HIV-1 PR.</p>Fórmula:C30H37N3O4Cor e Forma:SolidPeso molecular:503.63HIV-1 integrase inhibitor 9
CAS:<p>HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.</p>Fórmula:C18H12N2O10Cor e Forma:SolidPeso molecular:416.3Reverse transcriptase-IN-4
<p>Reverse transcriptase-IN-4: potent, selective NNRT inhibitor; EC50 = 0.053 μM for HIV-1, 0.26 μM for E138K mutant.</p>Fórmula:C17H21N5OSCor e Forma:SolidPeso molecular:343.45Rovafovir Etalafenamide
CAS:<p>Rovafovir Etalafenamide is a prodrug of anti-HIV nucleoside phosphonate.</p>Fórmula:C21H24FN6O6PPureza:98%Cor e Forma:SolidPeso molecular:506.42SARS-CoV-IN-2
CAS:<p>SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor</p>Fórmula:C24H26ClFeN3OPureza:98%Cor e Forma:SolidPeso molecular:463.78HIV-1 inhibitor-23
CAS:<p>HIV-1 inhibitor-23 suppresses HIV reverse transcriptase, effective on wild-type (EC50: 24.9 nM) and K103N mutant (EC50: 10.4 nM), with in vitro stability.</p>Fórmula:C30H26N6O4SCor e Forma:SolidPeso molecular:566.63R 82150
CAS:<p>R 82150 is an antiviral and a member of the tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin-2(1H)-thione family.</p>Fórmula:C16H21N3SPureza:98%Cor e Forma:SolidPeso molecular:287.42DLC27-14
CAS:<p>DLC27-14 is an HIV-1 Nef specific protein disorder catalyzer.</p>Fórmula:C25H25NO4Cor e Forma:SolidPeso molecular:403.47HIV-1 inhibitor-32
CAS:<p>HIV-1 inhibitor-32 is a potent inhibitor of HIV-1 that acts on wild-type HIV (IC50: 34 nM) and can be used in AIDS research.</p>Fórmula:C26H29N5O3SCor e Forma:SolidPeso molecular:491.61HIV-1 protease-IN-2
CAS:<p>HIV-1 protease-IN-2: strong HIV-1 protease blocker, IC50 2.53 nM, fights DRV-sensitive/resistant HIV-1.</p>Fórmula:C27H34N4O7SCor e Forma:SolidPeso molecular:558.65HIV-1 inhibitor-46
CAS:<p>HIV-1 inhibitor-46, compound 13d, is a potent non-nucleoside reverse transcriptase inhibitor with an EC50 of 1.425 μM, useful in AIDS research.</p>Fórmula:C24H21ClN4OSCor e Forma:SolidPeso molecular:448.97HIV-1 inhibitor-37
CAS:<p>HIV-1 inhibitor-37, a potent HIV-1 suppressant, shows promise as a novel latent reactivator.</p>Fórmula:C14H11Cl3N4OCor e Forma:SolidPeso molecular:357.62Tenofovir maleate
CAS:<p>Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B.</p>Fórmula:C13H18N5O8PCor e Forma:SolidPeso molecular:403.28Stampidine
CAS:<p>Stampidine prevents HIV-1, effective against resistant strains at subnanomolar levels.</p>Fórmula:C20H23BrN3O8PPureza:98%Cor e Forma:SolidPeso molecular:544.29HIV-1 inhibitor-30
CAS:<p>HIV-1 inhibitor-30 (10i) targets RT enzyme, EC50=40nM, IC50=80nM. Effective against seven NNRTI-resistant HIV-1 strains.</p>Fórmula:C19H20ClN3O2Cor e Forma:SolidPeso molecular:357.83Edelfosine
CAS:<p>inhibits phosphatidylinositol phospholipase C</p>Fórmula:C27H58NO6PPureza:98%Cor e Forma:SolidPeso molecular:523.73(+)-Dihydrocalanolide A
CAS:<p>DHCal A (NSC 678323) is an oral nonnucleoside Reverse Transcriptase inhibitor for HIV research.</p>Fórmula:C22H28O5Cor e Forma:SolidPeso molecular:372.45HIV-IN-5
CAS:<p>HIV-IN-5 (5r) inhibits HIV-1 with 0.16 μM IC50, targeting NNIBP as a NNRTI.</p>Fórmula:C30H24N2O8SCor e Forma:SolidPeso molecular:572.59HIV-1 inhibitor-47
CAS:<p>HIV-1 Inhibitor-47 blocks Vif-APOBEC3G interaction, has 14.33 μM IC50, and may yield antianxiety and antipsychotic derivatives.</p>Fórmula:C12H14N6Cor e Forma:SolidPeso molecular:242.28L 870810
CAS:<p>L 870810 is a small-molecule inhibitor of HIV-1 integrase with potent antiviral activity in cell culture and good pharmacokinetic properties.</p>Fórmula:C20H19FN4O4SCor e Forma:SolidPeso molecular:430.45HIV-1 protease-IN-5
CAS:<p>HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.</p>Fórmula:C27H29F3N2O7SCor e Forma:SolidPeso molecular:582.59DPC-963
CAS:<p>DPC-963 is a RNA-directed DNA polymerase inhibitor.</p>Fórmula:C14H9F5N2OCor e Forma:SolidPeso molecular:316.23Brecanavir
CAS:<p>Brecanavir is a tyrosyl-based arylsulfonamide, high affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type 1.</p>Fórmula:C33H41N3O10S2Cor e Forma:SolidPeso molecular:703.82ZINC04177596
CAS:<p>ZINC04177596 is a novel Nef Protein Inhibitor with anti-HIV activity.</p>Fórmula:C22H16N6O4Cor e Forma:SolidPeso molecular:428.4HIV-1 inhibitor-42
CAS:<p>HIV-1 inhibitor-42 (5b) strongly blocks HIV-1 (IC50: 0.06μM) and its RT RNA/DNA polymerases (IC50: 0.518/0.072μM).</p>Fórmula:C22H20N2O5SCor e Forma:SolidPeso molecular:424.47EP39
<p>EP39 is a potent HIV-1 inhibitor, stabilizing the SP1 domain's helix and blocking virus maturation.</p>Fórmula:C38H62N2O5Cor e Forma:SolidPeso molecular:626.91SJ-3366
CAS:<p>SJ3366 is a unique and highly potent nonnucleoside reverse transcriptase human immunodeficiency virus type 1 and HIV-2 inhibitor.</p>Fórmula:C21H24N2O3Cor e Forma:SolidPeso molecular:352.43HIV-1 protease-IN-1
CAS:<p>HIV-1 protease-IN-1, potent HIV inhibitor; IC50=90pM, fights B/C-HIV strains with EC50=89-13.59/8.23nM.</p>Fórmula:C25H35N3O6SCor e Forma:SolidPeso molecular:505.63VEC-5
CAS:<p>VEC-5: an HIV-1 inhibitor, outperforms RN18 by better binding with Vif in studies.</p>Fórmula:C29H21NO4Pureza:98%Cor e Forma:SolidPeso molecular:447.48HIV-1 inhibitor-38
CAS:<p>HIV-1 inhibitor-38, or Compound 91, shows promise as a strong latency reversing agent against HIV-1.</p>Fórmula:C15H13Cl3N6Cor e Forma:SolidPeso molecular:383.66A3N19
CAS:<p>A3N19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase and is able to act on HIV-1 IIIB (EC50: 3.28 nM).</p>Fórmula:C31H31N9O2SCor e Forma:SolidPeso molecular:593.7DMJ-I-228
CAS:<p>DMJ-I-228 is a specific inhibitor of HIV-1 entry through interaction with the Env spike by virtue of the incorporation of a guandinium group.</p>Fórmula:C19H19ClFN5O4Cor e Forma:SolidPeso molecular:435.84gp120-IN-2
CAS:<p>gp120-IN-2 is a potent HIV-1 inhibitor (IC50 = 7.5 μM) with low cytotoxicity (CC50 = 112.93 μM).</p>Fórmula:C15H18N2O5Cor e Forma:SolidPeso molecular:306.31A 80987
CAS:<p>A 80987 is an inhibitor of HIV-1 protease.</p>Fórmula:C37H43N5O6Cor e Forma:SolidPeso molecular:653.77GW-695634
CAS:<p>GW-695634, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C26H21Cl2N3O6SCor e Forma:SolidPeso molecular:574.43
