HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 506 produtos de "HIV Protease"
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Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Fórmula:C25H17N7O2Pureza:99.61%Cor e Forma:SolidPeso molecular:447.45Ref: TM-T12715
1mg64,00€5mg131,00€10mg183,00€25mg311,00€50mg449,00€100mg615,00€200mg833,00€1mL*10mM (DMSO)143,00€L-689502
CAS:L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).Fórmula:C39H51N3O7Pureza:98%Cor e Forma:SolidPeso molecular:673.84DGKα-IN-8
CAS:DGKα-IN-8 (Example 51) is a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 of 22.491 nM and an EC50 of 0.256 nM.Fórmula:C23H19ClF3N5OCor e Forma:SolidPeso molecular:473.88HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFórmula:C26H37N3O5SPureza:98%Cor e Forma:SolidPeso molecular:503.65HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Fórmula:C25H35N3O5SPureza:98%Cor e Forma:SolidPeso molecular:489.63HIV-1 inhibitor-10
CAS:HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.Fórmula:C39H54O6Cor e Forma:SolidPeso molecular:618.84BMS-955176 HCl
CAS:GSK-3532795: a broader-spectrum HIV-1 maturation inhibitor than bevirimat, effective in vitro and clinically.Fórmula:C42H62N2O4SCor e Forma:SolidPeso molecular:727.486Ulonivirine
CAS:Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.Fórmula:C18H8ClF6N5O3Cor e Forma:SolidPeso molecular:491.73Teropavimab
CAS:Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].Cor e Forma:LiquidAzt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Fórmula:C20H25N6O8PPureza:98%Cor e Forma:SolidPeso molecular:508.42HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Fórmula:C68H104N10O12SPureza:98%Cor e Forma:SolidPeso molecular:1285.68U 104489
CAS:U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.Fórmula:C26H36N6O3SCor e Forma:SolidPeso molecular:512.67Cgp 57813
CAS:CGP 57813 is a lipophilic compound, which can be used as an inhibitor of HIV-1 protease.Fórmula:C43H58N4O8Cor e Forma:SolidPeso molecular:758.94Berlopentin
CAS:Berlopentin is splenopentin analog used to treat HIV-positive patients. It also has immunostimulatory properties.Fórmula:C35H55N9O11Cor e Forma:SolidPeso molecular:777.86Capravirine
CAS:Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C20H20Cl2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:451.37Rp-dGTPαS
CAS:Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].Fórmula:C10H16N5O12P3SCor e Forma:SolidPeso molecular:523.253′-Deoxy Thymidine
CAS:3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC50 = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.Fórmula:C10H14N2O4Pureza:99.89%Cor e Forma:SolidPeso molecular:226.23L-697661
CAS:L-697661, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C16H15Cl2N3O2Cor e Forma:SolidPeso molecular:352.22HIV-IN-8
CAS:HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].Fórmula:C36H30O16Cor e Forma:SolidPeso molecular:718.61HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Fórmula:C25H35N3O5SPureza:98%Cor e Forma:SolidPeso molecular:489.63
