HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 451 produtos de "HIV Protease"
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HIV p17 Gag (77-85)
CAS:<p>Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.</p>Fórmula:C44H72N10O15Pureza:98%Cor e Forma:SolidPeso molecular:981.1Globotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Fórmula:C60H113NO18Cor e Forma:SolidPeso molecular:1136.553SPD-756
CAS:<p>SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C12H16N6O3Pureza:98%Cor e Forma:SolidPeso molecular:292.29Scirpusin A
CAS:<p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>Fórmula:C28H22O7Cor e Forma:SolidPeso molecular:470.47HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Cor e Forma:SolidPeso molecular:452.51Salvianan A
CAS:<p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>Fórmula:C20H17NO2Cor e Forma:SolidPeso molecular:303.35VRC01LS
<p>VRC01LS is a humanized monoclonal antibody inhibitor that targets the CD4 binding site of the HIV-1 envelope glycoprotein (Env). By blocking the interaction between HIV-1 and the host cell's CD4 receptor, VRC01LS inhibits viral entry. It holds potential for research in HIV-1 infection.</p>Cor e Forma:Odour LiquidDitiocarb
CAS:<p>Ditiocarb speeds up copper cementation, cuts HIV risk, and boosts high-risk breast cancer immunoresearch.</p>Fórmula:C5H11NS2Cor e Forma:SolidPeso molecular:149.28HIV protease-IN-1
CAS:<p>HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1].</p>Fórmula:C39H40ClF7N10O7Cor e Forma:SolidPeso molecular:929.24Epicoccone B
CAS:<p>Epicoccone B from C. globosum has DPPH scavenging (IC50=10.8μM) and α-glucosidase inhibition (IC50=27.3μM), also anti-HIV.</p>Fórmula:C9H8O5Cor e Forma:SolidPeso molecular:196.16Bictegravir Sodium
CAS:<p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>Fórmula:C21H17F3N3NaO5Pureza:99.97%Cor e Forma:SolidPeso molecular:471.36TAT peptide
<p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>Fórmula:C65H124N34O15Pureza:98%Cor e Forma:SolidPeso molecular:1621.91Peritassine A
CAS:<p>Peritassine A, an alkaloid derived from Tripterygium wilfordii Hook. f., exhibits anti-HIV properties.</p>Fórmula:C38H47NO18Cor e Forma:SolidPeso molecular:805.783Indoline
CAS:<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C8H9NCor e Forma:Clear To Yellow LiquidPeso molecular:119.16Lopinavir Metabolite M-1
CAS:<p>Lopinavir Metabolite M-1, derived from Lopinavir, inhibits HIV protease (Ki=0.7 pM) and shows antiviral activity in vitro.</p>Fórmula:C37H46N4O6Cor e Forma:SolidPeso molecular:642.78Hypoglaunine D
CAS:<p>Hypoglaunine D, an anti-HIV analogue of Triptonine B, inhibits HIV in H9 cells with an EC50 of 22 μg/ml.</p>Fórmula:C41H47NO19Cor e Forma:SolidPeso molecular:857.81HIV-1 protease-IN-4
HIV-1 protease-IN-4, a prodrug of atazanavir, delivers 5x AUC & 67x C24 compared to atazanavir.Fórmula:C48H69N7O11Cor e Forma:SolidPeso molecular:920.1(+)-Carbovir triphosphate
CAS:<p>(+)-Carbovir triphosphate, Abacavir's active metabolite, studied for HIV-1 resistance and inhibition mechanisms.</p>Fórmula:C11H16N5O11P3Cor e Forma:SolidPeso molecular:487.19HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Cor e Forma:Odour SolidEnfuvirtide
CAS:Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.Fórmula:C204H301N51O64Pureza:98%Cor e Forma:White To Off-White Amorphous SolidPeso molecular:4491.945
