Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3365 produtos de "Antibacteriano"
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HC2210
CAS:HC2210 exhibits antibacterial effects against Mycobacterium abscessus (Mab) with an EC50 of 0.72 µM. It modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is applicable for studies on Mab infections.Fórmula:C17H18N4O9Cor e Forma:SolidPeso molecular:422.35Aquayamycin
CAS:Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Fórmula:C25H26O10Cor e Forma:SolidPeso molecular:486.47LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Fórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41PptT-IN-1
PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.Fórmula:C18H29N5O2Cor e Forma:SolidPeso molecular:347.46PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89Rf470 TFA
CAS:Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Fórmula:C28H31F3N4O7SCor e Forma:SolidPeso molecular:624.63MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Fórmula:C15H13N3O4SCor e Forma:SolidPeso molecular:331.35FG-2101
CAS:FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Fórmula:C30H32N5O6PCor e Forma:SolidPeso molecular:589.579Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Fórmula:C22H27N3OSCor e Forma:SolidPeso molecular:381.53Diploicin
CAS:Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).
Fórmula:C16H10Cl4O5Cor e Forma:SolidPeso molecular:424.06GSK-3036656 free base
CAS:GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.Fórmula:C10H13BClNO4Cor e Forma:SolidPeso molecular:257.48NBTI 5463
CAS:NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Fórmula:C25H30N6O4Cor e Forma:SolidPeso molecular:478.54PptT-IN-3
PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.Fórmula:C16H27N5O3SCor e Forma:SolidPeso molecular:369.48Anti-MRSA agent 23
CAS:Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.Fórmula:C20H17N5O3SCor e Forma:SolidPeso molecular:407.446RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Fórmula:C12H10F2OCor e Forma:SolidPeso molecular:208.2Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31Enzyme-IN-3 disodium
CAS:Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Fórmula:C20H13N3Na2O8S2Cor e Forma:SolidPeso molecular:533.442MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Fórmula:C23H24ClN3O3Cor e Forma:SolidPeso molecular:425.91NFC nitro probe 1
CAS:NFC nitro probe 1 (compound 18) is a chemical probe designed for the detection of Mtb, exhibiting high potency against both R-Mtb and NR-Mtb.Fórmula:C19H19NO6Cor e Forma:SolidPeso molecular:357.357Probenecid sodium
CAS:Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.Fórmula:C13H18NNaO4SCor e Forma:SolidPeso molecular:307.341MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Fórmula:C22H24N4O3Cor e Forma:SolidPeso molecular:392.45Antibacterial agent 262
CAS:Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.Fórmula:C17H18F2N6O4S3Cor e Forma:SolidPeso molecular:504.554PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Fórmula:C22H29N5O2Cor e Forma:SolidPeso molecular:395.5Cephalosporin C
CAS:Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.
Fórmula:C16H21N3O8SCor e Forma:SolidPeso molecular:415.418Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Fórmula:C14H7Cl2F3N2OCor e Forma:SolidPeso molecular:347.12Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Fórmula:C25H36N6O8SPureza:99.85%Cor e Forma:SolidPeso molecular:580.65Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Fórmula:C27H33Cl2FN4O8Pureza:95% - 99.68%Cor e Forma:SolidPeso molecular:631.48Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Fórmula:C12H15N5O9S2Pureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:437.41LeuRS-IN-1 hydrochloride
CAS:LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Fórmula:C19H22N2O8Cor e Forma:SolidPeso molecular:406.39Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46α-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.25CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Fórmula:C19H21Br2Cl2N3O2SCor e Forma:SolidPeso molecular:586.16Lenampicillin hydrochloride
CAS:Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFórmula:C21H24ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:497.95Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Fórmula:C35H61NO12Pureza:98%Cor e Forma:White Amorphous Powder SolidPeso molecular:687.86Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Fórmula:C9H15NO3Cor e Forma:SolidPeso molecular:185.223Cefadroxil (hydrate)
CAS:Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Fórmula:C16H19N3O6SCor e Forma:White Crystalline SolidPeso molecular:381.404N-(3-(Dimethylamino)propyl)tetradecanamide
CAS:N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Fórmula:C19H40N2OCor e Forma:SolidPeso molecular:312.542Dusquetide
CAS:Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Fórmula:C25H47N9O5Pureza:98%Cor e Forma:SolidPeso molecular:553.709Phosalacine
CAS:Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.367Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Fórmula:C14H19N3OPureza:98%Cor e Forma:SolidPeso molecular:245.32Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Fórmula:C16H16FN3O3SCor e Forma:SolidPeso molecular:349.381-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Fórmula:C14H11F2NO4Cor e Forma:SolidPeso molecular:295.2382Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Fórmula:C18H26OCor e Forma:SolidPeso molecular:258.4MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Fórmula:C23H22N2O7Pureza:98%Cor e Forma:SolidPeso molecular:438.43Zabofloxacin hydrochloride
CAS:Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Fórmula:C19H21ClFN5O4Pureza:98%Cor e Forma:SolidPeso molecular:437.86Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Fórmula:C12H13NO5SCor e Forma:SolidPeso molecular:283.3Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Fórmula:C26H44O8Pureza:98%Cor e Forma:SolidPeso molecular:484.62Cefetamet pivoxyl
CAS:Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Fórmula:C20H25N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:511.57Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Fórmula:C21H28ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:501.981-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Fórmula:C11H10OCor e Forma:SolidPeso molecular:158.2Sulfamonomethoxine sodium
CAS:Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Fórmula:C11H11N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:302.29Pulcherriminic acid
CAS:Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42trans-Clopenthixol dihydrochloride
CAS:Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.892-Mercaptopyridine N-oxide sodium
CAS:2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Fórmula:C24H20ClNO3Cor e Forma:SolidPeso molecular:405.87FtsZ-IN-10
CAS:Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Fórmula:C15H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:352.79N-Butylthiophosphoric triamide
CAS:N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.21Ciprofloxacin lactate
CAS:Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Fórmula:C20H24FN3O6Cor e Forma:SolidPeso molecular:421.43TP0586532
CAS:TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Fórmula:C26H28N4O4Pureza:98%Cor e Forma:SolidPeso molecular:460.52d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Fórmula:C21H21N7OSPureza:98%Cor e Forma:SolidPeso molecular:419.5
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