Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3364 produtos de "Antibacteriano"
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MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Cor e Forma:SolidPeso molecular:373.18MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Fórmula:C23H18Cl2FNO3Cor e Forma:SolidPeso molecular:446.3RhlR antagonist 1
RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.Fórmula:C12H10F2OCor e Forma:SolidPeso molecular:208.2Carbonic anhydrase inhibitor 28
Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.Fórmula:C24H24FN5O7SCor e Forma:SolidPeso molecular:545.54ZG297
CAS:ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.Fórmula:C31H35F3N4O3Cor e Forma:SolidPeso molecular:568.63MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Fórmula:C16H23N3O9Cor e Forma:SolidPeso molecular:401.37Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31NDM-1 inhibitor-5
CAS:NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Fórmula:C24H23NO4Cor e Forma:SolidPeso molecular:389.44MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Fórmula:C23H24ClN3O3Cor e Forma:SolidPeso molecular:425.91MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Fórmula:C22H24N4O3Cor e Forma:SolidPeso molecular:392.45Antibacterial agent 204
CAS:Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].Fórmula:C14H18N2Cor e Forma:SolidPeso molecular:214.31Rf470 TFA
CAS:Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Fórmula:C28H31F3N4O7SCor e Forma:SolidPeso molecular:624.63Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Fórmula:C20H12ClN3O5Cor e Forma:SolidPeso molecular:409.78(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at aFórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Fórmula:C15H13N3O4SCor e Forma:SolidPeso molecular:331.35Cetefloxacin
CAS:Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.Fórmula:C20H16F3N3O3Peso molecular:403.35FPI-1465
CAS:FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.Fórmula:C11H18N4O7SCor e Forma:SolidPeso molecular:350.35Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.47-Hydroxytropolone
CAS:7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Fórmula:C7H6O3Cor e Forma:SolidPeso molecular:138.12Xeruborbactam isoboxil
CAS:Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.Fórmula:C15H16BFO6Cor e Forma:SolidPeso molecular:322.093L 689065
CAS:L 689065 is a 5-lipoxygenase inhibitor.Fórmula:C35H33ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:597.17Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Fórmula:C29H18BrN3O2Cor e Forma:SolidPeso molecular:520.386Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Fórmula:C10H8BFO4Pureza:98%Cor e Forma:SolidPeso molecular:221.98Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Fórmula:C7H14N3NaO8SCor e Forma:SolidPeso molecular:323.26LeuRS-IN-1 hydrochloride
CAS:LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.
Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Fórmula:C27H33Cl2FN4O8Pureza:95% - 99.68%Cor e Forma:SolidPeso molecular:631.48Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Fórmula:C12H15N5O9S2Pureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:437.41Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Fórmula:C25H36N6O8SPureza:99.85%Cor e Forma:SolidPeso molecular:580.65Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Fórmula:C19H22N2O8Cor e Forma:SolidPeso molecular:406.39α-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.25l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Fórmula:C16H16FN3O3SCor e Forma:SolidPeso molecular:349.38Zabofloxacin hydrochloride
CAS:Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Fórmula:C19H21ClFN5O4Pureza:98%Cor e Forma:SolidPeso molecular:437.86Ciprofloxacin lactate
CAS:Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Fórmula:C20H24FN3O6Cor e Forma:SolidPeso molecular:421.43Cefetamet pivoxyl
CAS:Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Fórmula:C20H25N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:511.57N-Butylthiophosphoric triamide
CAS:N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.21Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Fórmula:C21H28ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:501.98N-(3-(Dimethylamino)propyl)tetradecanamide
CAS:N-(3-(Dimethylamino)propyl)tetradecanamide is a useful organic compound for research related to life sciences. The catalog number is T66531 and the CAS number is 45267-19-4.Fórmula:C19H40N2OCor e Forma:SolidPeso molecular:312.542Dusquetide
CAS:Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Fórmula:C25H47N9O5Pureza:98%Cor e Forma:SolidPeso molecular:553.7091-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Fórmula:C11H10OCor e Forma:SolidPeso molecular:158.2Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Fórmula:C9H15NO3Cor e Forma:SolidPeso molecular:185.223Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Fórmula:C12H13NO5SCor e Forma:SolidPeso molecular:283.3Lenampicillin hydrochloride
CAS:Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skinFórmula:C21H24ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:497.95Sulfamonomethoxine sodium
CAS:Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].Fórmula:C11H11N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:302.29CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Fórmula:C19H21Br2Cl2N3O2SCor e Forma:SolidPeso molecular:586.16Pulcherriminic acid
CAS:Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30Phosalacine
CAS:Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.367FtsZ-IN-10
CAS:Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.Fórmula:C15H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:352.79Cefadroxil (hydrate)
CAS:Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.Fórmula:C16H19N3O6SCor e Forma:White Crystalline SolidPeso molecular:381.404Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Fórmula:C35H61NO12Pureza:98%Cor e Forma:White Amorphous Powder SolidPeso molecular:687.861-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Fórmula:C14H11F2NO4Cor e Forma:SolidPeso molecular:295.23822-Mercaptopyridine N-oxide sodium
CAS:2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Fórmula:C18H26OCor e Forma:SolidPeso molecular:258.4PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Fórmula:C24H20ClNO3Cor e Forma:SolidPeso molecular:405.87trans-Clopenthixol dihydrochloride
CAS:Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.89MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Fórmula:C23H22N2O7Pureza:98%Cor e Forma:SolidPeso molecular:438.43Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Fórmula:C14H19N3OPureza:98%Cor e Forma:SolidPeso molecular:245.32Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Fórmula:C26H44O8Pureza:98%Cor e Forma:SolidPeso molecular:484.62TP0586532
CAS:TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
Fórmula:C26H28N4O4Pureza:98%Cor e Forma:SolidPeso molecular:460.52Ribocil-C
CAS:Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Fórmula:C21H21N7OSPureza:98%Cor e Forma:SolidPeso molecular:419.5d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42
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