Antibacteriano

<p>Oxacillin sodium salt (Oxabel) is an antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.</p>

<p>Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.</p>

<p>Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.</p>

<p>Cefmetazole sodium: semisynthetic cephamycin, broad-spectrum, effective against infections, no severe side effects.</p>

<p>Sulfanilamide (UK-124) can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.</p>

<p>Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.</p>

<p>Ribocil selectively modulates bacterial riboswitches, inhibiting GFP with an EC50 of 0.3 μM.</p>

<p>Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor for the treatment of multi-drug resistant gram-negative bacterial infections.</p>

<p>Tilmicosin (EL-870), a macrolide antibiotic, treats bovine and ovine respiratory diseases in animals.</p>

<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>

<p>Meropenem (SM 7338), a broad-spectrum IV antibiotic, treats severe infections but may cause mild liver enzyme elevations or rare cholestatic injury.</p>

<p>NSC-60339: AcrAB-TolC substrate, efflux pump inhibitor, potential cancer drug.</p>

<p>Nitrofurantoin, an antibiotic, targets bacteria for urinary infections by blocking DNA, RNA, and protein synthesis.</p>

<p>Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.</p>

<p>Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic.</p>

<p>Prothionamide (1321-TH)is a thioamide derivative with antitubercular activity.</p>

<p>Cefotaxime: 3rd-gen cephalosporin antibiotic, broad-spectrum, similar to ceftriaxone, sold as Claforan.</p>

<p>Mafenide hydrochloride (4-Aminomethylbenzenesulfonamide hydrochloride) is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-</p>

<p>Fosfomycin calcium (Phosphomycin calcium salt) is a BBB penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.</p>

<p>Hyaluronic acid sodium (MW 2,000,000 kDa) is a high molecular hyaluronic acid sodium, with moisturizing effect, can form a thin layer on the surface of the skin, can slow down the evaporation of water from the surface of the skin.</p>

<p>Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.</p>

<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>

<p>Bronopol (BNPD): Low-toxicity antimicrobial, highly effective against Gram-negative bacteria.</p>

<p>Sulfamethoxypyridazine (CL 13494) is a sulfanilamide antibacterial agent.</p>

<p>Sulfaquinoxaline sodium salt (SQ-Na) is a veterinary broad-spectrum antimicrobial agent, which can be used to prevent coccidiosis and bacterial infections.</p>

<p>Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.</p>

<p>Lysostaphin is an anti-staph compound with 3 enzymes: endopeptidase, glucosamidase, amidase.</p>

<p>Sulfacetamide sodium (Sulamyd sodium) is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.</p>

<p>Pyrithione (1-hydroxyl-1H-pyridine-2-thione) is a transition metal complex, a zinc ionophore, that causes elevated zinc levels in mammalian cells.</p>

<p>Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that inhibits viral DNA replication after metabolization.</p>

<p>Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.</p>

<p>Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.</p>

<p>Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.</p>

<p>Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.</p>

<p>Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.</p>

<p>Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic β-Lactamase inhibitor.</p>

<p>Cefazolin sodium, a beta-lactam antibiotic, targets PBPs to disrupt bacterial cell wall synthesis, causing cell lysis.</p>

<p>(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].</p>

<p>A 83016A is a kinamycin-type antibiotic.</p>

<p>Platensimycin (PTM): S. platensis antibiotic, inhibits Gram-positive bacteria, blocks lipid making (IC50=0.1μM), may combat antibiotic resistance.</p>

<p>Antibacterial 128, a siderophore-Ciprofloxacin blend with cleavable linker, targets P. aeruginosa and B. pseudomallei.</p>

<p>PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.</p>

<p>1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.</p>

<p>2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences.</p>

<p>Alliacol B is an antibiotic with mild antibacterial and antifungal properties. It can inhibit DNA synthesis in Ehrlich ascites carcinoma cells.</p>

<p>Amoxicillin + potassium clavulanate (4:1) is a broad-spectrum, well-absorbed oral antibiotic blocking cell wall synthesis.</p>

<p>Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.</p>

<p>LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide, a growth hormone-releasing peptide antagonist, and a GHS-R1a inverse agonist</p>

<p>α-Lipomycin is an acyclic polyene antibiotic isolated from the Gram-positive bacterium Streptomyces aureofaciens Tü117.</p>

<p>FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs</p>

<p>Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.</p>

<p>Cyclacillin (Wy-4508), an oral aminopenicillin, fights many gram-positive/negative bacteria.</p>

<p>MMV1578877 is an inhibitor of Mycobacterium ulcerans with an IC50 of 0.37 μM. It is applicable in research related to Buruli ulcer (BU).</p>

<p>Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.</p>

<p>Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.</p>

<p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>

<p>Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.</p>

<p>Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.</p>

<p>1-Ethylnaphthalene exhibits antibacterial activity and can be used in biochemical experiments and drug synthesis.</p>

<p>Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.</p>

<p>AcrB-IN-1 (Compound H6) is a highly effective inhibitor of AcrB, utilized for the reversal of bacterial multidrug resistance [1].</p>

<p>Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].</p>

<p>Rose Bengal is a photosensitizer effective against microbial cells. In the presence of light and oxygen, it inhibits the growth of yeast cells and other microorganisms, sometimes leading to their death. Rose Bengal can also limit bacterial growth, restrict the colony size of filamentous fungi, and suppress the growth of "spreading fungi" such as Rhizopus and Trichoderma.</p>

<p>Ibericin, an anthraquinone from Prismatomeris filamentosa roots, exhibits antibacterial effects on Gram-positive and Gram-negative bacteria.</p>

<p>Mycobactin P is one of iron(III) chelating compounds produced by most species of Mycobacteria which act as growth factors.</p>

<p>(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].</p>

<p>Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.</p>

<p>Showdomycin is an antibiotic with antineoplastic activity.</p>

<p>LL-37, Human TFA (154947-66-7 free base) is a 37-residue amphipathic helical peptide, the sole human cathelicidin antimicrobial peptide, antibacterial.</p>

<p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>

<p>Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.</p>

<p>LL-37 scrambled peptide is a scrambled version of cathelicidin anti-microbial peptide LL-37.</p>

<p>Cefoperazone dihydrate, a semi-synthetic cephalosporin, exhibits a wide range of antibacterial properties.</p>

<p>Psicofuranine: a nucleoside antibiotic inhibiting GMP synthase and P. falciparum growth with an IC50 of 0.3 mM.</p>

<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>

<p>Polyunsaturated anacardic acid diene from cashew shells fights MRSA, S. mutans, and S. mansoni; inhibits soybean lipoxygenase-1.</p>

<p>Rubradirin B has an antibacterial activity similar to rubradirin, but the antibiotic is less active.</p>

<p>Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.</p>

<p>EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.</p>

<p>Olaquindox can be used in relevant research in the life sciences. Its product number is T2779 and CAS number is 23696-28-8.</p>

<p>LBM-415 is a peptide deformylase (PDF) inhibitor.</p>

<p>Nv-CATH, an antibacterial peptide derived from frogs, exhibits broad-spectrum activity against both gram-positive and gram-negative bacteria, and significantly</p>

<p>Lysozyme chloride: enzyme that kills gram-positive bacteria; used in HIV, emphysema research.</p>

<p>Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.</p>

<p>Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor balls</p>

<p>Antibiotic tan-592B is an antibiotic agent.</p>

<p>Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.</p>

<p>Maximin 3, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Ascr#18: nematode hormone boosts infection resistance in plants like Arabidopsis, tomato, potato, barley.</p>

<p>SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.</p>

<p>Funalenone, from A. niger, inhibits HIV-1 integrase, HIV replication, and MMP-1, also curbing S. aureus growth. Less toxic to human cells.</p>

<p>Maximin 39, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus and Escherichia coli, demonstrating minimum</p>

<p>Thiotropocin is an antibiotic.</p>

<p>Ga(III)protoporphyrin-IX: soluble in MeOH, mimics malaria pigment, has strong antibacterial properties.</p>

<p>Angolamycin is a macrolide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>

<p>MBL-IN-1 (compound 41), a β-Lactamase inhibitor, exhibits an IC50 range of 0.10 to 25.85 µM and is utilized in the study of bacterial infections [1].</p>

<p>RvD4, derived from docosahexaenoic acid, reduces neutrophil infiltration and promotes phagocytosis/clearance by human cells.</p>

<p>Flagelin 22, a bacterial flagellin fragment, serves as a potent elicitor for plants and algae.</p>

<p>broad spectrum antibiotic</p>

<p>Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.</p>