Antibacteriano

<p>Globomycin: a lipopeptide antibiotic that irreversibly inhibits signal peptidase II, blocking prolipoprotein processing.</p>

<p>Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.</p>

<p>Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.</p>

<p>Isepamicin (Sch 21420) is a strong aminoglycoside antibiotic, effective on Enterobacteriaceae and staphylococci, less so on other bacteria.</p>

<p>CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and</p>

<p>(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].</p>

<p>Adipic dihydrazide (ADH) is a dihydrazide a bifunctional cross-linking agent for water-in-oil emulsions and a curing agent for epoxy resins.</p>

<p>Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.</p>

<p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>

<p>FPI-1523 inhibits β-lactamase (Kd: CTX-M-15 = 4 nM, OXA-48 = 34 nM), blocks PBP2 (IC50 = 3.2 μM), and has strong antimicrobial effects.</p>

<p>Framycetin is an aminoglycoside antibiotic and it also inhibits hammerhead ribozyme (Ki: 13.5 μM).</p>

<p>Monensin, from Streptomyces cinnamonensis, inhibits Wnt/β-catenin. Potential anticancer agent.</p>

<p>Aibellin is a peptide antibiotic and serves as an effective and beneficial modulator of rumen fermentation.</p>

<p>TP0586352 is a potent inhibitor of LpxC, exhibiting efficacy against carbapenem-resistant strains of Klebsiella pneumoniae without inducing cardiovascular risks</p>

<p>Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.</p>

<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>

<p>Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.</p>

<p>Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.</p>

<p>Lysozyme chloride: enzyme that kills gram-positive bacteria; used in HIV, emphysema research.</p>

<p>Rubradirin B has an antibacterial activity similar to rubradirin, but the antibiotic is less active.</p>

<p>Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.</p>

<p>Albocycline, a macrolide antibiotic from S. bruneogriseus MCRL-0129, targets staph including resistant strains.</p>

<p>Arylomycin B4 is a lipidic hexapeptide antibiotic (antibiotic) targeting Gram-positive bacteria.</p>

<p>Azidocillin, a semi-synthetic oral β-lactam antibiotic, treats various bacterial infections including osteitis and septicemia.</p>

<p>Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.</p>

<p>Aurein 3.1 is an antibiotic antimicrobial peptide, whereas Aurein 2.6 demonstrates activity against Gram-positive bacteria, exhibiting minimum inhibitory</p>

<p>T-91825 (PPI-0903M), an active N-phosphono cephalosporin, is potent against various bacteria and stems from TAK-599.</p>

<p>NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) has antimicrobial activity, inhibits the proliferation of C. albicans, and is used in diabetes.</p>

<p>Telithromycin is a macrolide antibiotic and erythromycin derivative,70S bacterial ribosome, antimicrobial, respiratory infections,inhibits protein synthesis.</p>

<p>Tazobactam sodium,β-Lactamase inhibitor.</p>

<p>Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, demonstrates a high efficacy against S.</p>

<p>Cefoperazone dihydrate, a semi-synthetic cephalosporin, exhibits a wide range of antibacterial properties.</p>

<p>Rifamycin: Natural antibiotic; blocks prokaryotic RNA synthesis by halting RNA-polymerase.</p>

<p>Antituberculosis agent-7: active against P. mirabilis (MIC 31.25μM), A. niger (MIC 62.5μM), and M. tuberculosis (MIC 3.41μM).</p>

<p>Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.</p>

<p>LBM-415 is a peptide deformylase (PDF) inhibitor.</p>

<p>Candicidin, a heptaene macrolide from S. griseus or A. levoris, treats candidiasis topically. Mainly candicidin D.</p>

<p>Oxiran-2-ylmethanol exhibits antibacterial activity against Escherichia coli and can be used in related research in the field of life sciences.</p>

<p>Clostomycin B2 is a bioactive chemical.</p>

<p>Amoxycillin arginine salt is a bioactive chemical.</p>

<p>SC 28538, a 5-nitroimidazole, matches metronidazole in potency against multiple pathogens in vitro.</p>

<p>Capoamycin is an insotatracine antibiotic investigated for anti tumor properties.</p>

<p>Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].</p>

<p>Alliacol B is an antibiotic with mild antibacterial and antifungal properties. It can inhibit DNA synthesis in Ehrlich ascites carcinoma cells.</p>

<p>SCH 38519, a fungal metabolite, inhibits thrombin, serotonin in platelets, and bacteria growth.</p>

<p>A unique collection of xnum anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-</p>

<p>Maximin 3, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Ascr#18: nematode hormone boosts infection resistance in plants like Arabidopsis, tomato, potato, barley.</p>

<p>Compd 3j (Antibacterial agent 149) is a laccase inhibitor that exhibits potent fungicidal activity, particularly useful in researching rice sheath blight [1].</p>

<p>17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical</p>

<p>Lysobactin (katanosin B) is an antibiotic effective against S. aureus, S. pneumoniae, and blocks PG biosynthesis.</p>

<p>RvD4, derived from docosahexaenoic acid, reduces neutrophil infiltration and promotes phagocytosis/clearance by human cells.</p>

<p>Angolamycin is a macrolide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>

<p>Compound 14, also known as Tuberculosis Inhibitor 11, enhances the antimycobacterial efficacy of antitubercular agent [1].</p>

<p>Platensimycin (PTM): S. platensis antibiotic, inhibits Gram-positive bacteria, blocks lipid making (IC50=0.1μM), may combat antibiotic resistance.</p>

<p>Antibiotic tan-592B is an antibiotic agent.</p>

<p>Bryostatin 1, a marine macrolide, permeates CNS and modulates PKC, with strong affinity for Munc13-1 (Ki: 8.07 nM and 0.45 nM).</p>

<p>Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor balls</p>

<p>Renierone is an antimicrobial metabolite isolated from the marine sponge, Reniera sp.</p>

<p>Maximin 5, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.</p>

<p>Sirpefenicol (ZTS-00007928), a phenicol antibacterial for treating animal bacterial infections.</p>

<p>Dermaseptin is a peptide expressed by the frog skin glands with a potent antimicrobial activity against bacteria, fungi and protozoa.</p>

<p>Mram 8, a cyclotide isolated from Viola philippica of the Violaceae family [1], exhibits a characteristic cyclic peptide structure.</p>

<p>Dusquetide TFA (SGX942) is an IDR that modulates immunity by targeting p62, reducing inflammation, and enhancing bacterial clearance.</p>

<p>Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.</p>

<p>Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn.</p>

<p>Amythiamicin A is an antibiotic effective against gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), and exhibits activity against Plasmodium falciparum.</p>

<p>Cethromycin (ABT-773) is an antibiotic of ketolide.</p>

<p>Rabelomycin is an angucycline group antibiotic.</p>

<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>

<p>Aurein 5.2 is an antibiotic antimicrobial peptide [1].</p>

<p>Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range</p>

<p>Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.</p>

<p>Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.</p>

<p>Ga(III)protoporphyrin-IX: soluble in MeOH, mimics malaria pigment, has strong antibacterial properties.</p>

<p>Linearmycin B, a polyene antibiotic from Streptomyces, causes B. subtilis lysis in Streptomyces Mg1 extract.</p>

<p>Alamethicin F50, a 20-amino acid peptaibol from Trichoderma, forms ion channels and has lytic and antibacterial properties.</p>

<p>(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].</p>

<p>Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.</p>

<p>2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences.</p>

<p>Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against</p>

<p>Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria [1] [2].</p>

<p>6-C-Methylquercetin-3,4'-dimethyl ether is a flavonol derivative extracted from Bauhinia thonningii Schum leaves, displaying antibacterial effects on Gram-</p>

<p>Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces. It is a homolog of nonactin from the same species.</p>

<p>Tuberculosis inhibitor 9 (compound 3d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and</p>

<p>D13-9001, an antibiotic, inhibits AcrB and MexB with KDs of 1.15μM in E. coli and 3.57μM in P. aeruginosa.</p>

<p>Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.</p>

<p>PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.</p>

<p>XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.</p>

<p>Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.</p>

<p>Cefoselis hydrochloride is a widely used beta-lactam antibiotic.</p>

<p>Agent 38 from patent WO2015063714A1 (C) serves as an antibacterial for scientific study.</p>

<p>Compound 1b, also known as Antibacterial agent 145, targets the bacterial iron uptake pathway to exert its effects.</p>

<p>Pazufloxacin (T-3761) is a broad-spectrum fluoroquinolone antibiotic effective against various infections, including strains resistant to other quinolones.</p>

<p>Ledaborbactam etzadroxil (VNRX-7145) is an orally active inhibitor of Ambler class A, C, and D β-lactamase enzymes.</p>

<p>GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.</p>

<p>Deacetylnomilin is a useful organic compound for research related to life sciences. The catalog number is T125039 and the CAS number is 3264-90-2.</p>

<p>Desacetylcefotaxime, a Cefotaxime metabolite, has strong antimicrobial effects against various bacteria.</p>

<p>Arylomycin B6 is a lipoglycopeptide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>