Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3308 produtos de "Antibacteriano"
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PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Fórmula:C22H29N5O2Cor e Forma:SolidPeso molecular:395.514α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C26H22N4O4Cor e Forma:SolidPeso molecular:454.48Antimicrobial agent-29
CAS:Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].Fórmula:C19H14N4O4SCor e Forma:SolidPeso molecular:394.4MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Fórmula:C26H35FN16O2Pureza:98%Cor e Forma:SolidPeso molecular:622.66KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Fórmula:C12H10BN3O2SCor e Forma:SolidPeso molecular:271.1MtTMPK-IN-7
MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.Fórmula:C27H29ClN6O3Cor e Forma:SolidPeso molecular:521.01Eravacycline
CAS:Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.Fórmula:C27H31FN4O8Pureza:97.46%Cor e Forma:SolidPeso molecular:558.56Benzisothiazolone
CAS:Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Fórmula:C7H5NOSCor e Forma:SolidPeso molecular:151.19NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48Diclosulam
CAS:Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Fórmula:C13H10Cl2FN5O3SCor e Forma:SolidPeso molecular:406.22DNA Gyrase-IN-16
CAS:<p>DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.</p>Fórmula:C17H15N3O3Cor e Forma:SolidPeso molecular:309.319FPI-1465
CAS:FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.Fórmula:C11H18N4O7SCor e Forma:SolidPeso molecular:350.35Fabimycin
CAS:Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Fórmula:C23H25ClN4O3Cor e Forma:SolidPeso molecular:440.92Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.Fórmula:C17H19N5O5Cor e Forma:SolidPeso molecular:373.363Metallo-β-lactamase-IN-16
CAS:Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Fórmula:C16H16N8O4S3Cor e Forma:SolidPeso molecular:480.54Antibacterial agent 110
Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).Fórmula:C22H21N5O4SCor e Forma:SolidPeso molecular:451.5Aurantiogliocladin
CAS:Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.Fórmula:C10H12O4Cor e Forma:SolidPeso molecular:196.2Atramycin A
CAS:Atramycin A is an anthraquinone antibiotic with antitumor properties.Fórmula:C25H24O9Cor e Forma:SolidPeso molecular:468.453HC2210
CAS:HC2210 exhibits antibacterial effects against Mycobacterium abscessus (Mab) with an EC50 of 0.72 µM. It modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is applicable for studies on Mab infections.Fórmula:C17H18N4O9Cor e Forma:SolidPeso molecular:422.35
