Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3334 produtos de "Antibacteriano"
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MtTMPK-IN-3
CAS:MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.Fórmula:C23H23Cl2N3O3Cor e Forma:SolidPeso molecular:460.35Cefoxazole
CAS:Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.Fórmula:C21H18ClN3O7SCor e Forma:SolidPeso molecular:491.902Metallo-β-lactamase-IN-16
CAS:Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.Fórmula:C16H16N8O4S3Cor e Forma:SolidPeso molecular:480.54RNAP-σ interaction inhibitor-2
CAS:RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Fórmula:C27H19Cl3N2O6S2Cor e Forma:SolidPeso molecular:637.939InhA-IN-7
CAS:InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].
Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.Fórmula:C17H19N5O5Cor e Forma:SolidPeso molecular:373.363Altersolanol A
CAS:Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.Fórmula:C16H16O8Cor e Forma:SolidPeso molecular:336.29Isotodesnitazene
CAS:Isotodesnitazene is an opioid compound that primarily targets the μ-opioid receptor (MOR). It exhibits EC50 values of 34.8 nM and 142 nM for MOR-βarr2 and MOR-mini-Gi, respectively. Isotodesnitazene can be utilized for research in opioid drugs.Fórmula:C23H31N3OCor e Forma:SolidPeso molecular:365.51Tuberculosis inhibitor 4
TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.Fórmula:C23H26N2O3SCor e Forma:SolidPeso molecular:410.53Cefclidin
CAS:Cefclidin (Cefclidine) is a cephalosporin compound.Fórmula:C21H26N8O6S2Cor e Forma:SolidPeso molecular:550.611Antibacterial agent 63
CAS:Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to aFórmula:C35H43N9O14S2Cor e Forma:SolidPeso molecular:877.94-Bromo A23187
CAS:4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Fórmula:C29H36BrN3O6Pureza:98%Cor e Forma:SolidPeso molecular:602.52DNA gyrase B-IN-1
DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.Fórmula:C23H18ClF3N6O4SCor e Forma:SolidPeso molecular:566.94(1S,2R,7S)-Sitafloxacin
CAS:(1S,2R,7S)-Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin and functions as a topoisomerase inhibitor. As an antibiotic, it demonstrates inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S)-Sitafloxacin exhibits antibacterial properties and is utilized in the study of various bacterial infections.Fórmula:C19H18ClF2N3O3Cor e Forma:SolidPeso molecular:409.81Antibacterial agent 236
CAS:Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.Fórmula:C26H27N5O2SCor e Forma:SolidPeso molecular:473.59MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Fórmula:C16H23N3O9Cor e Forma:SolidPeso molecular:401.37Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Fórmula:C29H18BrN3O2Cor e Forma:SolidPeso molecular:520.386NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48NusB-IN-1
NusB-IN-1 (22r) is an oral bacterial rRNA inhibitor, effective against MRSA and VRSA.Fórmula:C21H16N2O3Cor e Forma:SolidPeso molecular:344.36
