Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3334 produtos de "Antibacteriano"
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MRL-494
MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.
Fórmula:C26H35FN16O2Pureza:98%Cor e Forma:SolidPeso molecular:622.66Antibacterial agent 90
Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.Fórmula:C30H42N2O6Cor e Forma:SolidPeso molecular:526.66MtTMPK-IN-7
MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.Fórmula:C27H29ClN6O3Cor e Forma:SolidPeso molecular:521.01Alpibectir
CAS:Alpibectir has antibacterial activity [1].Fórmula:C12H14F6N2O2Cor e Forma:SolidPeso molecular:332.24Diclosulam
CAS:Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Fórmula:C13H10Cl2FN5O3SCor e Forma:SolidPeso molecular:406.22Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Fórmula:C23H24N6OCor e Forma:SolidPeso molecular:400.48Squalamine lactate
CAS:Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Fórmula:C37H71N3O8SPureza:98%Cor e Forma:SolidPeso molecular:718.04Dioxidine
CAS:Dioxidine is an antimicrobial agent that can inhibit bacterial growth. It is utilized in research on pyogenic infections.Fórmula:C10H10N2O4Cor e Forma:SolidPeso molecular:222.197(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Fórmula:C17H37N7O3Cor e Forma:SolidPeso molecular:387.52MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Cor e Forma:SolidPeso molecular:373.18Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49DRF-8417
CAS:DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.Fórmula:C15H17N3O5SCor e Forma:SolidPeso molecular:351.38ROS inducer 9
CAS:ROS inducer 9 (compound 4e) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 0.25 μg/mL against Escherichia coli. It eradicates bacteria by inhibiting GSH activity and increasing ROS levels. Additionally, ROS inducer 9 exhibits low toxicity toward red blood cells and RAW 264.7 cells.Fórmula:C26H26BrF4N3O3Cor e Forma:SolidPeso molecular:584.401NS-062
CAS:NS-062 is an orally effective, irreversible covalent inhibitor targeting EGFR, demonstrating antiproliferative activity in the resistant double mutant H1975 cells with an IC50 of 0.19 μM. It also exhibits antitumor activity in a murine H1975 xenograft model.Fórmula:C28H30Cl2F2N6O4Cor e Forma:SolidPeso molecular:623.48Atramycin A
CAS:Atramycin A is an anthraquinone antibiotic with antitumor properties.Fórmula:C25H24O9Cor e Forma:SolidPeso molecular:468.453Fostriecin (free base)
CAS:Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Fórmula:C19H27O9PCor e Forma:SolidPeso molecular:430.39Antibacterial agent 62
Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.Fórmula:C24H33BrN2O2Cor e Forma:SolidPeso molecular:461.44Topoisomerase inhibitor 5
CAS:Topoisomerase inhibitor 5 (compound 158) is an inhibitor of bacterial topoisomerase, with a minimum inhibitory concentration of 0.125 μg/mL, and exhibits anti-tuberculosis activity.Fórmula:C24H25FN4O6Cor e Forma:SolidPeso molecular:484.477Quorum sensing-IN-9
CAS:Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.Fórmula:C9H10OS2Cor e Forma:SolidPeso molecular:198.305Keto lovastatin
CAS:Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Fórmula:C24H34O6Cor e Forma:SolidPeso molecular:418.523
