Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3334 produtos de "Antibacteriano"
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Cilastatin ammonium salt
CAS:Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.Fórmula:C16H29N3O5SCor e Forma:SolidPeso molecular:375.48DNA ligase-IN-2
CAS:DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.Fórmula:C13H8FN3O3Cor e Forma:SolidPeso molecular:273.219Diploicin
CAS:Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).
Fórmula:C16H10Cl4O5Cor e Forma:SolidPeso molecular:424.06MsbA-IN-4
MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).Fórmula:C23H18Cl2FN5OCor e Forma:SolidPeso molecular:470.33BioA-IN-1
CAS:BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.Fórmula:C18H17NO3SCor e Forma:SolidPeso molecular:327.397trans-Clopenthixol
CAS:Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.Fórmula:C22H25ClN2OSCor e Forma:SolidPeso molecular:400.965Antibacterial agent 266
CAS:Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.Fórmula:C13H11N3OCor e Forma:SolidPeso molecular:225.246MsbA-IN-5
MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.Fórmula:C23H19Cl2N5OCor e Forma:SolidPeso molecular:452.34KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Fórmula:C12H10BN3O2SCor e Forma:SolidPeso molecular:271.1Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Fórmula:C30H35NO11Cor e Forma:SolidPeso molecular:585.60Antibiofilm agent-14
CAS:Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.Fórmula:C26H30ClN3OCor e Forma:SolidPeso molecular:435.989Antibacterial agent 174
CAS:Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].Fórmula:C25H30FN2NaO5Cor e Forma:SolidPeso molecular:480.5Aurantiogliocladin
CAS:Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.Fórmula:C10H12O4Cor e Forma:SolidPeso molecular:196.2LolCDE-IN-2
CAS:LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Fórmula:C22H17N5OPureza:98%Cor e Forma:SolidPeso molecular:367.40Anti-MRSA agent 27
CAS:Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.Fórmula:C15H10F3N3OSCor e Forma:SolidPeso molecular:337.32PptT-IN-1
PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.Fórmula:C18H29N5O2Cor e Forma:SolidPeso molecular:347.46β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Fórmula:C21H17Cl3O7Cor e Forma:SolidPeso molecular:487.71Pisiferic acid
CAS:Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoidFórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.43Antibacterial agent 66
Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.Fórmula:C17H10ClF6N3O2SCor e Forma:SolidPeso molecular:469.79MsbA-IN-3
MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).Fórmula:C24H22Cl2N2O4SCor e Forma:SolidPeso molecular:505.41
