Antibacteriano

<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>

<p>Ro-23-9424, a cephalosporin with fleroxacin at 3' and aminothiazolylmethoxyimino at 7, exhibits strong broad-spectrum antibacterial effects.</p>

<p>Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.</p>

<p>EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.</p>

<p>Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.</p>

<p>Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.</p>

<p>Polyunsaturated anacardic acid diene from cashew shells fights MRSA, S. mutans, and S. mansoni; inhibits soybean lipoxygenase-1.</p>

<p>Calcimycin (A-23187) is an antibiotic calcium ionophore that raises intracellular Ca2+ to induce cell death.</p>

<p>Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.</p>

<p>Maximin 4, an antimicrobial peptide from Bombina maxima skin secretions, exhibits cytotoxic effects on tumor cells and spermicidal properties [1].</p>

<p>Psicofuranine: a nucleoside antibiotic inhibiting GMP synthase and P. falciparum growth with an IC50 of 0.3 mM.</p>

<p>Albocycline, a macrolide antibiotic from S. bruneogriseus MCRL-0129, targets staph including resistant strains.</p>

<p>Compound A11 is a potent antibacterial, with MIC 0.00191 μg/mL against MRSA, outperforming tiamulin and retapamulin by 162x and 32x.</p>

<p>Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.</p>

<p>Sparsomycin is an antitumor antibiotic. It also inhibits protein synthesis in the 70S and 80S ribosomal systems.</p>

<p>Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.</p>

<p>(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].</p>

<p>Sperabillin A (free base) is a potent antibacterial antibiotic in vivo isolated from Pseudomonas fluorescens YK-437.</p>

<p>Compound 12: potent antimicrobial with 2-8 μg/mL MIC, effective against Gram-positive/negative bacteria; anti-inflammatory.</p>

<p>Showdomycin is an antibiotic with antineoplastic activity.</p>

<p>Samandarone is a major alkaloid from the European fire salamander (Salamandra salamandra terrestris).</p>

<p>Bagougeramine B is an orally active nucleoside antibiotic with antibacterial properties, discovered in Bacillus circulans. It inhibits the growth of both Gram-positive and Gram-negative bacteria, as well as some fungi.</p>

<p>Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd oxidase, acts as an antibiotic against malaria, Plasmodium spp.</p>

<p>Paldimycin A is a semi-synthetic antibiotic from Streptomyces paulus.</p>

<p>Pirlimycin Hydrochloride, a Clindamycin analog, is a semi-synthetic lincosaminide antibiotic.</p>

<p>Antiangiogenic agent 8 (Compound 3m) functions as both an antibacterial agent and an antiangiogenic compound. It shows minimum inhibitory concentrations (MIC) of 16, 8, 4, 16, and 8 μg/mL against E. coli, P. aeruginosa, B. subtilis, S. aureus, and C. glabrata, respectively, with minimum bactericidal concentrations (MBC) ranging from 32 to 64 μg/mL. This compound holds potential for applications in infection control and cardiovascular disease research.</p>

<p>Kasugamycin is an antibiotic that acts by binding within the mRNA channel of the 30S subunit and inhibiting protein synthesis.</p>

<p>Rose Bengal is a photosensitizer effective against microbial cells. In the presence of light and oxygen, it inhibits the growth of yeast cells and other microorganisms, sometimes leading to their death. Rose Bengal can also limit bacterial growth, restrict the colony size of filamentous fungi, and suppress the growth of "spreading fungi" such as Rhizopus and Trichoderma.</p>

<p>Clostomycin B2 is a bioactive chemical.</p>

<p>Cefpirome: fourth-gen cephalosporin, broad-spectrum, inactivates penicillin-binding proteins in bacteria.</p>

<p>Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.</p>

<p>Kapurimycin A3 is an antitumor antibiotics.</p>

<p>Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria.</p>

<p>Mram 8, a cyclotide isolated from Viola philippica of the Violaceae family [1], exhibits a characteristic cyclic peptide structure.</p>

<p>Cis-β-Terpineol, a monoterpene derived from the aerial parts of Anthemis turcomanica, exhibits antibacterial activity as evidenced by studies on the stems,</p>

<p>Rabelomycin is an angucycline group antibiotic.</p>

<p>P-113 is a peptide with antimicrobial activity.</p>

<p>Monocerin, from F. larvarum, combats E. coli, B. megaterium, M. violaceum, C. fusca; kills C. erythrocephala; hinders S. halepense root growth.</p>

<p>17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical</p>

<p>α-Lipomycin is an acyclic polyene antibiotic isolated from the Gram-positive bacterium Streptomyces aureofaciens Tü117.</p>

<p>Chloramine-T (Chloralone) is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.</p>

<p>Compound 14, also known as Tuberculosis Inhibitor 11, enhances the antimycobacterial efficacy of antitubercular agent [1].</p>

<p>Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against</p>

<p>Amoxicillin + potassium clavulanate (4:1) is a broad-spectrum, well-absorbed oral antibiotic blocking cell wall synthesis.</p>

<p>Ro 09-1428, a parenteral cephalosporin, has high antipseudomonal activity.</p>

<p>1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.</p>

<p>Altromycin G is a new pluramycin-like antibiotic.</p>

<p>Angolamycin is a macrolide antibiotic (antibiotic) effective against Gram-positive bacteria.</p>

<p>Cefoperazone dihydrate, a semi-synthetic cephalosporin, exhibits a wide range of antibacterial properties.</p>

<p>Rubradirin: an antibiotic targeting methicillin-resistant staph, complex structure, inhibits peptide initiation.</p>