Antibacteriano

Polymyxin B2 is an antibiotic primarily utilized for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa.

HS-291 is a HtpG inhibitor targeting Borrelia burgdorferi (Bb), composed of BX-2819 (high affinity for Bb HtpG), a PEG linker, and Verteporfin (a photoactive

Asperglaucid A: a phthalide-like compound with strong antibacterial effects against Pseudomonas syringae pv actinidae and Bacillus cereus; MIC: 6.25 μM.

Griseoluteic acid is a breakdown product of griseolutein A and B. Griseoluteic acid is a phenazine antibiotic and is originally isolated from S. griseoluteus.

Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.

Maximin 63, an antimicrobial peptide sourced from toad brain, exhibits potent efficacy against Staphylococcus aureus with a minimum inhibitory concentration (

Sterigmatocystine, a G1 phase and DNA synthesis inhibitor, curbs p21 and is a mycotoxin precursor from Aspergillus versicolor.

Talaromycesone A, from Talaromyces, fights S. epidermidis & MRSA (IC50: 3.7 & 5.48 μM), inhibits AChE (IC50: 7.49 μM).

Prodigiosin hydrochloride is a bioactive red pigment from bacteria with antibacterial, antifungal, anticancer properties, and inhibits Wnt/β-catenin.

2,4-Dihydroxyphenylacetyl-L-asparagine is a natural product for research related to life sciences.

Nafcillin sodium, a penicillin antibiotic, treats Gram-positive, penicillin-resistant staph infections.

AA35 boosts Ceftazidime's efficacy by lowering its MIC.

Ro 41-1879 is a catechol cephalosporin with antimicrobial activity.

Bombinin H2, an antimicrobial peptide sourced from Bombina variegata skin, exhibits potential for combating microbial infections [1].

Cecropin B is a small antibacterial peptide from the giant silkmoth, Hyalophora cecropia.

Rabelomycin is an angucycline group antibiotic.

Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor balls

Compound 7a: potent, selective MRSA growth inhibitor; MIC ≤ 0.26 µM; non-cytotoxic, non-hemolytic.

α-Lipomycin is an acyclic polyene antibiotic isolated from the Gram-positive bacterium Streptomyces aureofaciens Tü117.

2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.

17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical

Cefluprenam is a a cephalosporin type antibacterial agent.

Viroxocin, a diterpenoid, is isolated from the roots of Salvia viridis L. cvar. Blue Jeans and exhibits weak antibacterial activity [1].

Enopeptin A: depsipeptide antibiotic with unique amino acids, combats Gram-positive/negative bacteria, not antifungal.

K 41 is a polycyclic polyether antibiotic from Streptomyces hygroscopicus.

Compound 14, also known as Tuberculosis Inhibitor 11, enhances the antimycobacterial efficacy of antitubercular agent [1].

Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent.

Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against

Reltecimod TFA (AB-103 TFA) is a CD28 antagonist and mimetic, inhibiting the stimulation of t-cells thereby attenuating acute inflammation NSTI.

Bactobolin is a biochemical.

Amoxicillin + potassium clavulanate (4:1) is a broad-spectrum, well-absorbed oral antibiotic blocking cell wall synthesis.

Repromicin is a chemical compound whose derivatives have strong antibacterial characteristics.

Cefmetazole is a second-generation semi-synthetic β-lactam cephalosporin antibiotic with antimicrobial activity.

Ceratotoxin A is a 29-residue peptide extracted from the accessory gland secretion fluid, known for its potent antibacterial properties.

Tur1A, an antimicrobial peptide sourced from the bottlenose dolphin (Tursiops truncates), impedes bacterial protein synthesis.

Antibacterial agent 136, an oxadiazolone antibiotic, highly potent against MRSA with MIC 50 at 0.8 μM.

Angolamycin is a macrolide antibiotic (antibiotic) effective against Gram-positive bacteria.

(2E,4E)-Decadienoic acid, an aliphatic anti-oomycete agent, is present in the coculture of Bacillus subtilis and Trichoderma asperellum [1].

FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs

Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.

Mtb-IN-10 (Compound P15) is an Rv1625c/Cya activator that influences the growth of Mycobacterium tuberculosis (Mtb) by modulating cAMP metabolism. It demonstrates an anti-tuberculosis activity with an EC50 of 1.96 µM in Mtb-infected macrophage models and achieves an oral bioavailability of 58.0% when administered orally to mice at 20 mg/kg. Mtb-IN-10 potentially regulates intracellular signaling and disrupts cholesterol metabolism within Mtb, thereby inhibiting bacterial proliferation. It holds promise for tuberculosis (TB) research, particularly targeting multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains of Mtb.

KT5823 is a cGMP-dependent protein kinase (PKG) inhibitor that increases iodide ion uptake by regulating the expression of sodium iodide symporter protein.

Ascr#18: nematode hormone boosts infection resistance in plants like Arabidopsis, tomato, potato, barley.

FLGFVGQALNALLGKL-NH2, an antimicrobial peptide derived from frogs, exhibits activity against Staphylococcus aureus ATCC 29213 with a minimum inhibitory

AA45 boosts Ceftazidime's efficacy by lowering its MIC value, showcasing strong antibacterial properties.

RvD4, derived from docosahexaenoic acid, reduces neutrophil infiltration and promotes phagocytosis/clearance by human cells.

Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn.