Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 2968 produtos de "Antibacteriano"
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Caspofungin
CAS:<p>Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.</p>Fórmula:C52H88N10O15Cor e Forma:SolidPeso molecular:1093.31Antibacterial agent 65
CAS:<p>Antibacterial agent 65 is a potential antimicrobial agent and antioxidant agent.</p>Fórmula:C17H16O3Cor e Forma:SolidPeso molecular:268.31Antimicrobial agent-6
<p>Antimicrobial agent-6: MIC 4-8 μg/mL for gram+ & gram- bacteria, anti-inflammatory.</p>Fórmula:C40H64N16Cor e Forma:SolidPeso molecular:769.04c-di-AMP
CAS:<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Fórmula:C20H24N10O12P2Pureza:98%Cor e Forma:SolidPeso molecular:658.41Metallo-β-lactamase-IN-8
CAS:<p>Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity.</p>Fórmula:C13H11ClN2O4SCor e Forma:SolidPeso molecular:326.76GlcN-6-P Synthase-IN-1
CAS:<p>'GlcN-6-P Synthase-IN-1, IC50 3.47 μM, inhibits GlcN-6-P synthase & CYP3A4. Has antimicrobial activity and CNS penetration.'</p>Fórmula:C20H21N7SCor e Forma:SolidPeso molecular:391.49Antibacterial agent 64
CAS:<p>Potent antibacterial, YycG inhibitor with 6.1 µM IC50. Synergistic with ampicillin against biofilm bacteria.</p>Fórmula:C29H20ClN3O6S2Cor e Forma:SolidPeso molecular:606.07SMR000071098
CAS:<p>SMR000071098 is an inhibitor of Fe-S cluster-dependent aconitase. SMR000071098 interacts with Suf proteins to inhibit iron-sulfur (Fe-S) cluster assembly.</p>Fórmula:C17H12N2O2Cor e Forma:SolidPeso molecular:276.29Anti-infective agent 1
CAS:<p>Compound 3a: potent, selective antiprotozoal/antimycobacterial. IC50: P. falciparum 10.95 μM, T. brucei 0.06 μM. MIC against M. smegmatis: 8 μg/mL.</p>Fórmula:C16H10O2Cor e Forma:SolidPeso molecular:234.25Antiproliferative agent-17
CAS:Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].Fórmula:C26H28N2OSCor e Forma:SolidPeso molecular:416.58Topoisomerase IV inhibitor 1
CAS:<p>Compound 7d: Inhibits TOPO IV (IC50: 0.23 μM), DNA gyrase (IC50: 0.43 μM), antibacterial against S. aureus (MIC: 0.972 μM), E. coli (MIC: 0.608 μM).</p>Fórmula:C34H32FN7O6SPureza:98%Cor e Forma:SolidPeso molecular:685.72ACP1b
CAS:<p>ACP1b is an activator of ClpP protease.</p>Fórmula:C18H18ClF3N2O3S2Cor e Forma:SolidPeso molecular:466.93TBI-166
CAS:<p>TBI-166, an oral riminophenazine, treats tuberculosis with fewer side effects than Clofazimine.</p>Fórmula:C32H30F3N5O3Cor e Forma:SolidPeso molecular:589.61OYYF-175
CAS:<p>OYYF-175: potent antimicrobial antifolate; targets multi-drug resistant Gram-Negative bacteria; DHFR inhibitor with 2.36 nM IC50 against E. coli.</p>Fórmula:C17H14FN5Cor e Forma:SolidPeso molecular:307.33Polyketide synthase 13-IN-2
CAS:<p>Comp 42 is a potent PKS13 inhibitor in M. tuberculosis with MIC of 0.25 μg/mL.</p>Fórmula:C22H21NO5Cor e Forma:SolidPeso molecular:379.41SARS-CoV-2 3CLpro-IN-3
CAS:SARS-CoV-2 3CLpro-IN-3 is a SARS CoV-2 3CLpro inhibitor that exhibits antiviral, antibacterial, and antifungal effects.Fórmula:C23H21BrN6O2SCor e Forma:SolidPeso molecular:525.42CBR-6672
CAS:<p>CBR-6672, a potent anti-tuberculosis agent; type II NADH dehydrogenase inhibitor; MIC: 0.14 μM.</p>Fórmula:C17H20FN3O2SCor e Forma:SolidPeso molecular:349.42MurA-IN-2
CAS:<p>MurA-IN-2: potent MurA inhibitor, IC50 of 39μM, chloroacetamide with aliphatic amine; has antibacterial properties.</p>Fórmula:C12H20ClNOCor e Forma:SolidPeso molecular:229.75Arasertaconazole
CAS:<p>Arasertaconazole, a sterol-14-alpha demethylation inhibitor, is used potentially for the treatment of vulvovaginal candcanidiasis.</p>Fórmula:C20H15Cl3N2OSCor e Forma:SolidPeso molecular:437.77TMV-IN-1
CAS:<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Fórmula:C28H26O4Cor e Forma:SolidPeso molecular:426.5DNA Gyrase-IN-5
CAS:<p>DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.</p>Fórmula:C25H15BrClN5Cor e Forma:SolidPeso molecular:500.78BTZ-N3
CAS:<p>BTZ-N3 is an effective and selective anti-tuberculosis drug candidate.</p>Fórmula:C17H16F3N5O3SCor e Forma:SolidPeso molecular:427.4Salazopyridazine
CAS:<p>Salazopyridazine is an antibacterial agent that inhibits ulcerative colitis. salazopyridazine can be used in the study of rheumatic diseases.</p>Fórmula:C18H15N5O6SCor e Forma:SolidPeso molecular:429.41P516-0475
CAS:<p>P516-0475, a novel inducer, enhances Streptococcus quorum sensing by blocking PepO, stabilizing SHP pheromones.</p>Fórmula:C15H17N5O3Cor e Forma:SolidPeso molecular:315.33Methdilazine Hydrochloride
CAS:<p>Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist for dermatologic conditions and relief of itching by allergies or rhinitis.</p>Fórmula:C18H21ClN2SCor e Forma:Light-Tan Crystalline Powder 4 8-6 (Ntp 1992)Peso molecular:332.89Antibacterial agent 121
CAS:<p>Antibacterial agent 121 exhibits anti-TB and anti-inflammatory properties.</p>Fórmula:C18H22N2O3SCor e Forma:SolidPeso molecular:346.44Cefepime chloride
CAS:<p>Cefepime chloride, a broad-spectrum cephalosporin, combats Gram-positive/negative bacteria and can induce neurotoxicity.</p>Fórmula:C19H25ClN6O5S2Cor e Forma:SolidPeso molecular:517.02BPH-1086
CAS:<p>BPH-1086 inhibits IspH, which with RPS1 binds mRNA or integrates into bacterial ribosomes.</p>Fórmula:C4H8O7P2Cor e Forma:SolidPeso molecular:230.05Antibacterial agent 97
CAS:<p>Antibacterial agent 97 is potent; MIC: 16 μg/mL for E. coli and S. aureus.</p>Fórmula:C19H23N5SCor e Forma:SolidPeso molecular:353.48Type II topoisomerase inhibitor 1
CAS:<p>Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).</p>Fórmula:C18H15N3O4Cor e Forma:SolidPeso molecular:337.33MurA-IN-3
CAS:<p>MurA-IN-3, a reversible pyrrolidinedione-based MurA inhibitor, exhibits an IC50 of 4.5 μM against MurA and demonstrates antibacterial activity [1].</p>Fórmula:C27H23ClN2O5SCor e Forma:SolidPeso molecular:523Antitubercular agent-26
CAS:<p>Compound 32: oral antitubercular, acts on M. tuberculosis, IC50 ~0.50μM, stable, low cardiotoxicity, non-genotoxic.</p>Fórmula:C22H23N5O3S2Cor e Forma:SolidPeso molecular:469.58Antitubercular agent-14
CAS:<p>Antitubercular agent-14 (Compound 1) shows antitubercular activity. The MIC value of Antitubercular agent-14 against M. tuberculosis is 0.3 μg/mL [1].</p>Fórmula:C20H27ClN2Cor e Forma:SolidPeso molecular:330.89Anticandidal agent-1
CAS:<p>Compound C2 is a broad-spectrum anticandidal, blocking biofilm and filament growth with MIC50 of 13.51μg/mL (C. glabrata) and 8.65μg/mL (C. albicans).</p>Fórmula:C19H22O5Cor e Forma:SolidPeso molecular:330.38Berteroin
CAS:<p>Berteroin, found in cruciferous veggies like rucola and mustard, may act as an antioxidant, reducing inflammation and androgen receptors in cancer.</p>Fórmula:C7H13NS2Cor e Forma:SolidPeso molecular:175.31ATD-3169
CAS:<p>ATD-3169 is a ROS generator with antibacterial activity.</p>Fórmula:C15H14O3Pureza:98%Cor e Forma:SolidPeso molecular:242.27Antimicrobial agent-3
CAS:<p>Antimicrobial agent-3 (Compound U10) is an antimicrobial agent that is used against bacterial, fungal, and tubercular infections [1].</p>Fórmula:C14H11N3OSCor e Forma:SolidPeso molecular:269.32Metallo-β-lactamase-IN-4
CAS:<p>Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and</p>Fórmula:C10H14N4O3S2Cor e Forma:SolidPeso molecular:302.37Antibacterial agent 122
CAS:<p>Thiourea derivative 122 is a low-toxicity antibacterial used in tuberculosis research with anti-mycobacterial properties.</p>Fórmula:C15H14N2O3SCor e Forma:SolidPeso molecular:302.35Cadrofloxacin
CAS:<p>Cadrofloxacin (Caderofloxacin, CS-940) is a novel fluoroquinolone antimicrobial agent.</p>Fórmula:C19H20F3N3O4Cor e Forma:SolidPeso molecular:411.38C16-K-cBB1
<p>C16-K-cBB1: potent, selective MRSA killer; MIC 1µg/mL, low hemolysis, works in 120 min at 12.5µg/mL.</p>Fórmula:C33H58ClN5O5SCor e Forma:SolidPeso molecular:672.36Metallo-β-lactamase-IN-2
CAS:<p>Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for</p>Fórmula:C9H9Cl2NOSCor e Forma:SolidPeso molecular:250.14Metallo-β-lactamase-IN-6
CAS:<p>Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2</p>Fórmula:C10H9N3O2Cor e Forma:SolidPeso molecular:203.2CL-55
CAS:<p>CL-55 is a novel inhibitor of T3SS.</p>Fórmula:C19H17F2N3O4SCor e Forma:SolidPeso molecular:421.42Mt KARI-IN-2
CAS:<p>Mt KARI-IN-2, an inhibitor for Mtb KARI (Ki: 2.02 μM) and Mtb H37Rv (MIC: 0.78 μM), has low cytotoxicity (HEK IC50: >86 μg/mL).</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4LpxC-IN-9
CAS:<p>LpxC-IN-9 (compound 19) is a potent inhibitor of LpxC and exhibits antibacterial and hypotensive activity.</p>Fórmula:C23H25N5O3SCor e Forma:SolidPeso molecular:451.54Antibacterial agent 104
CAS:<p>Antibacterial agent 104 is an effective antibacterial agent with significant antibacterial effects in vitro and good anti-MRSA effects in vivo.</p>Fórmula:C28H39NO4SCor e Forma:SolidPeso molecular:485.68Antibacterial agent 105
CAS:<p>Compound 17, a phenanthrolinic quinolone, fights M. tuberculosis (MIC 90: 2.64 μM) and various bacteria (MIC 90: 0.70-44.70 μM).</p>Fórmula:C14H9N3O5Cor e Forma:SolidPeso molecular:299.24Antibacterial agent 95
CAS:<p>Antibacterial 95, a quinoline-derived antituberculotic, shows 0.3 μM MIC against Mycobacterium tuberculosis H37Rv and inhibits its growth in macrophages.</p>Fórmula:C19H16ClNO3Cor e Forma:SolidPeso molecular:341.79Metallo-β-lactamase-IN-9
CAS:<p>Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM</p>Fórmula:C13H12N6O3SCor e Forma:SolidPeso molecular:332.34
