Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 2957 produtos de "Antibacteriano"
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Antibiofilm agent-9
CAS:<p>Antibiofilm agent-9 (Compound 4), a derivative of pyrrolnitrin, exhibits antimicrobial activity. It inhibits Bacillus anthracis with a Minimum Inhibitory Concentration (MIC) of 0.031 μg/mL. The compound demonstrates significant antibiofilm activity, achieving an inhibition rate of 84% after 24 hours at a concentration of 8.0 μg/mL. Additionally, Antibiofilm agent-9 shows favorable pharmacokinetic properties in mouse models.</p>Fórmula:C11H5BrCl2FNO2Cor e Forma:SolidPeso molecular:352.97Deacylketoconazole
CAS:<p>Deacylketoconazole (Deacyl ketoconazole) is a Ketoconazole derivative and is also an antifungal agent.</p>Fórmula:C24H26Cl2N4O3Pureza:98.35%Cor e Forma:SolidPeso molecular:489.39Anti-MRSA agent 5
CAS:<p>Potent anti-MRSA compound, MIC50: 0.38 μg/mL, minimal hERG activity (IC50: 40 μM), low toxicity, and resistance unlikely.</p>Fórmula:C25H22N4O4Cor e Forma:SolidPeso molecular:442.47Targeting the bacterial sliding clamp peptide 46
CAS:<p>Peptide 46 is a short peptide that inhibits SC-dependent DNA synthesis by targeting the bacterial sliding clamp (SC).</p>Fórmula:C47H64N8O11Cor e Forma:SolidPeso molecular:917.06Antimicrobial photosensitizer-1
CAS:<p>Photosensitizer-1 shows promise in treating infections, effective against S. aureus in mouse wounds.</p>Fórmula:C19H19BF2I3N3Cor e Forma:SolidPeso molecular:718.9Cochliodone A
CAS:<p>Cochliodone A, a bioactive compound isolated from the deep-sea fungus Chaetomium sp., exhibits both antibacterial and anticancer properties.</p>Fórmula:C34H38O12Cor e Forma:SolidPeso molecular:638.66LS-BF1
CAS:<p>LS-BF1: Stable, low-toxic antimicrobial peptide targeting ESKAPE pathogens via cell membrane disruption, effective in mouse infection model.</p>Fórmula:C107H166N28O15Cor e Forma:SolidPeso molecular:2084.64BO 2367
CAS:<p>BO 2367, a topoisomerase inhibitor, is used to suppress the growth of tumor .</p>Fórmula:C21H22ClF2N3O3Cor e Forma:SolidPeso molecular:437.87Antibacterial agent 92
<p>Antibacterial agent 92 inhibits Salmonella's aaRS; IC50 of 0.58 μM for Se ThrRS. Exhibits antibacterial effects.</p>Fórmula:C30H28Cl2F3N5O4Cor e Forma:SolidPeso molecular:650.48G43-C3-TEG
CAS:<p>G43-C3-TEG is a glycosyl-transferase inhibitor that diminishes biofilm formation by inhibiting the synthesis of extracellular polysaccharides (EPS) [1].</p>Fórmula:C24H27N3O9SCor e Forma:SolidPeso molecular:533.55Biotin-cholesterol
CAS:<p>Biotin-cholesterol, a biotinylated derivative of cholesterol, serves as a precursor in the manufacturing of biotin-conjugated liposomes and micelles, which are utilized in drug delivery systems [1].</p>Fórmula:C37H60N2O3SCor e Forma:SolidPeso molecular:612.95Roseoflavin
CAS:<p>Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the</p>Fórmula:C18H23N5O6Pureza:99.81% - 99.89%Cor e Forma:SolidPeso molecular:405.41Ianthelliformisamine B TFA
CAS:<p>Ianthelliformisamine B TFA, an antibiotic enhancer, is used to against resistant Gram-negative bacteria.</p>Fórmula:C21H27Br2F6N3O6Pureza:98%Cor e Forma:SolidPeso molecular:691.25WQ 2743
CAS:<p>WQ 2743 is a potent agent of antimicrobial.</p>Fórmula:C19H15BrF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:498.25Antibacterial agent 94
CAS:<p>Compound 5b, an antibacterial, effectively targets MRSA and disrupts bacterial membranes and PG synthesis.</p>Fórmula:C21H21FO4Cor e Forma:SolidPeso molecular:356.39Bio-AMS
CAS:<p>Bio-AMS is a potent inhibitor of bacterial biotin protein ligase, exhibiting selective activity against Mycobacterium tuberculosis (Mtb) and disrupting fatty</p>Fórmula:C20H29N9O7S2Cor e Forma:SolidPeso molecular:571.63Pristinamycin IA
CAS:<p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>Fórmula:C45H54N8O10Pureza:97.44%Cor e Forma:SolidPeso molecular:866.96Contezolid
CAS:<p>Contezolid (MRX-I) is an antibiotic with bactericidal activity and can be used to study tuberculosis.</p>Fórmula:C18H15F3N4O4Pureza:99.41%Cor e Forma:SolidPeso molecular:408.33Salicyl-AMS
CAS:<p>Salicyl-AMS is an inhibitor of mycobacterium auxin biosynthesis that inhibits the growth of mycobacterium in the presence of iron deficiency in vitro.</p>Fórmula:C17H18N6O8SPureza:98.19%Cor e Forma:SolidPeso molecular:466.43A7132
CAS:<p>A7132 is an antibacterial agent and possesses broad and potent antibacterial activity.</p>Fórmula:C19H16F2N4O3Pureza:95.49%Cor e Forma:SolidPeso molecular:386.35Elongation factor P-IN-1
<p>EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.</p>Fórmula:C14H31N3O2Cor e Forma:SolidPeso molecular:273.41Urease-IN-20
CAS:<p>Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 μM for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and γH2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.</p>Fórmula:C14H8FNO2SeCor e Forma:SolidPeso molecular:320.18Anti-MRSA agent 2
CAS:<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Fórmula:C18H10Br2N2OCor e Forma:SolidPeso molecular:430.09NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Fórmula:C16H12O4Pureza:98.66%Cor e Forma:SolidPeso molecular:268.26Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Fórmula:C10H6O5SCor e Forma:SolidPeso molecular:238.217Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Fórmula:C14H21N3S2Cor e Forma:SolidPeso molecular:295.47SPR719
CAS:<p>SPR719 is an inhibitor of gyrase B, has bactericidal activity.</p>Fórmula:C21H25FN6O3Pureza:98%Cor e Forma:SolidPeso molecular:428.46Antibacterial agent 99
CAS:<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Fórmula:C27H27BrN2Cor e Forma:SolidPeso molecular:459.42Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Fórmula:C31H34N2O7Cor e Forma:SolidPeso molecular:546.61Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Fórmula:C25H33NO2Cor e Forma:SolidPeso molecular:379.535(S)-ZG197
<p>(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at a</p>Fórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Fórmula:C15H16BFO6Cor e Forma:SolidPeso molecular:322.093L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Fórmula:C35H33ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:597.17Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Fórmula:C9H15N3O5Cor e Forma:SolidPeso molecular:245.23Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Fórmula:C17H12BrFN4O2SCor e Forma:SolidPeso molecular:435.27Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Fórmula:C22H28N6OCor e Forma:SolidPeso molecular:392.5RNAP-σ interaction inhibitor-1
CAS:<p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>Fórmula:C19H11Cl3N2O6S2Cor e Forma:SolidPeso molecular:533.79WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Fórmula:C22H22F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:461.44Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Fórmula:C18H27N3O2S3Cor e Forma:SolidPeso molecular:413.628-Deazafolic acid
CAS:<p>8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.</p>Fórmula:C20H20N6O6Pureza:98%Cor e Forma:SolidPeso molecular:440.41NBTIs-IN-4
<p>NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.</p>Fórmula:C22H24FN5O5SCor e Forma:SolidPeso molecular:489.52MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Fórmula:C23H18Cl2FNO3Cor e Forma:SolidPeso molecular:446.3ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Fórmula:C31H35F3N4O3Cor e Forma:SolidPeso molecular:568.63Antitubercular agent-22
<p>Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).</p>Fórmula:C24H28FN5O8Cor e Forma:SolidPeso molecular:533.51FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Fórmula:C21H16ClF2NO2Cor e Forma:SolidPeso molecular:387.81(1R,2S,7R)-Sitafloxacin
CAS:<p>(R)-Sitafloxacin (DU-6857) is an enantiomer of Sitafloxacin (DU-6859a) and functions as a topoisomerase inhibitor, demonstrating an IC50 of 0.18 μg/mL against DNA gyrase.</p>Fórmula:C19H18ClF2N3O3Cor e Forma:SolidPeso molecular:409.814Aeroplysinin 1
CAS:<p>Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation.</p>Fórmula:C9H9Br2NO3Cor e Forma:SolidPeso molecular:338.98ACHN-975 TFA
CAS:<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Fórmula:C22H24F3N3O6Pureza:98%Cor e Forma:SolidPeso molecular:483.4377QPX7728 methoxy acetoxy methy ester
CAS:<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C14H14BFO7Pureza:98%Cor e Forma:SolidPeso molecular:324.07
