Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 2949 produtos de "Antibacteriano"
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Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Fórmula:C16H11F2N3Cor e Forma:SolidPeso molecular:283.28HldA/E-IN-1
CAS:<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Fórmula:C8H17FO13P2Cor e Forma:SolidPeso molecular:402.16Antibacterial agent 259
CAS:<p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>Fórmula:C7H6ClN3O2SCor e Forma:SolidPeso molecular:231.659MsbA-IN-4
<p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>Fórmula:C23H18Cl2FN5OCor e Forma:SolidPeso molecular:470.33MsbA-IN-5
<p>MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.</p>Fórmula:C23H19Cl2N5OCor e Forma:SolidPeso molecular:452.34Antibiofilm agent-14
CAS:<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Fórmula:C26H30ClN3OCor e Forma:SolidPeso molecular:435.989Kendomycin
CAS:<p>Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.</p>Fórmula:C29H42O6Cor e Forma:SolidPeso molecular:486.64Fenbenicillin potassium
CAS:<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Fórmula:C22H22KN2O5SCor e Forma:SolidPeso molecular:465.584Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Fórmula:C14H11N3O4SCor e Forma:SolidPeso molecular:317.32Antibacterial agent 76
<p>Antibacterial agent 76 (compound 9) is a potent antibacterial agent.</p>Fórmula:C23H27N3O2SCor e Forma:SolidPeso molecular:409.54Antitubercular agent-13
<p>Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.</p>Fórmula:C18H18N4O5Cor e Forma:SolidPeso molecular:370.36FtsZ-IN-13
CAS:<p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>Fórmula:C18H14N2O4S2Cor e Forma:SolidPeso molecular:386.445MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Fórmula:C26H35FN16O2Pureza:98%Cor e Forma:SolidPeso molecular:622.66MtTMPK-IN-7
<p>MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.</p>Fórmula:C27H29ClN6O3Cor e Forma:SolidPeso molecular:521.01Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Fórmula:C8H12N2S2Cor e Forma:SolidPeso molecular:200.32DC-159a
CAS:<p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>Fórmula:C21H23F2N3O40·5H2OCor e Forma:SolidPeso molecular:428.4295Anticaries agent-1
CAS:<p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.253(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Fórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6MtTMPK-IN-8
<p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>Fórmula:C24H24N6O7Cor e Forma:SolidPeso molecular:508.48Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49ACHN-975
CAS:<p>ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.</p>Fórmula:C20H23N3O4Pureza:98%Cor e Forma:SolidPeso molecular:369.41Eravacycline
CAS:<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Fórmula:C27H31FN4O8Pureza:97.46%Cor e Forma:SolidPeso molecular:558.56Cetefloxacin
CAS:<p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>Fórmula:C20H16F3N3O3Peso molecular:403.35QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C15H14BFO8Pureza:98%Cor e Forma:SolidPeso molecular:352.08Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Fórmula:C17H10ClFN2Cor e Forma:SolidPeso molecular:296.73Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Fórmula:C25H24O9Cor e Forma:SolidPeso molecular:468.453Ro 24-4383
CAS:<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Fórmula:C32H31FN8O10S2Pureza:98%Cor e Forma:SolidPeso molecular:770.76Antibacterial agent 99
CAS:<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Fórmula:C27H27BrN2Cor e Forma:SolidPeso molecular:459.42MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Fórmula:C15H19N9O5S2Cor e Forma:SolidPeso molecular:469.50BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Fórmula:C18H17NO3SCor e Forma:SolidPeso molecular:327.397Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Fórmula:C31H34N2O7Cor e Forma:SolidPeso molecular:546.61Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Fórmula:C25H33NO2Cor e Forma:SolidPeso molecular:379.535Antibacterial agent 172
CAS:<p>Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>Fórmula:C21H21N9O5S2Cor e Forma:SolidPeso molecular:543.58(S)-ZG197
<p>(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at a</p>Fórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6Thiolactomycin
CAS:<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Fórmula:C11H14O2SPureza:98%Cor e Forma:SolidPeso molecular:210.29Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4Anti-MRSA agent 3
CAS:<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Fórmula:C29H18BrN3O2Cor e Forma:SolidPeso molecular:520.386Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Fórmula:C15H16BFO6Cor e Forma:SolidPeso molecular:322.093L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Fórmula:C35H33ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:597.17Pks13-TE inhibitor 4
CAS:<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Fórmula:C26H25N5O6Peso molecular:503.51NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Fórmula:C16H12O4Pureza:98.66%Cor e Forma:SolidPeso molecular:268.26844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48Anti-MRSA agent 2
CAS:<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Fórmula:C18H10Br2N2OCor e Forma:SolidPeso molecular:430.09OPC-167832
CAS:<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Fórmula:C21H20ClF3N2O4Cor e Forma:SolidPeso molecular:456.84Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Fórmula:C9H15N3O5Cor e Forma:SolidPeso molecular:245.23Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Fórmula:C17H12BrFN4O2SCor e Forma:SolidPeso molecular:435.27Antibacterial agent 75
<p>Antibacterial agent 75 re-sensitizes VRSA to vancomycin.</p>Fórmula:C22H28N6OCor e Forma:SolidPeso molecular:392.5Urease-IN-20
CAS:<p>Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 μM for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and γH2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.</p>Fórmula:C14H8FNO2SeCor e Forma:SolidPeso molecular:320.18RNAP-σ interaction inhibitor-1
CAS:<p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>Fórmula:C19H11Cl3N2O6S2Cor e Forma:SolidPeso molecular:533.79WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Fórmula:C22H22F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:461.44
