Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3286 produtos de "Antibacteriano"
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Anthelvencin A
CAS:Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.Fórmula:C19H25N9O3Cor e Forma:SolidPeso molecular:427.46Antibacterial agent 62
Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.Fórmula:C24H33BrN2O2Cor e Forma:SolidPeso molecular:461.44Atramycin A
CAS:Atramycin A is an anthraquinone antibiotic with antitumor properties.Fórmula:C25H24O9Cor e Forma:SolidPeso molecular:468.453Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49Meclocycline
CAS:Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.Fórmula:C22H21ClN2O8Cor e Forma:SolidPeso molecular:476.86Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Fórmula:C16H11F2N3Cor e Forma:SolidPeso molecular:283.28Kendomycin
CAS:Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Fórmula:C29H42O6Cor e Forma:SolidPeso molecular:486.64Antitubercular agent-13
Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.Fórmula:C18H18N4O5Cor e Forma:SolidPeso molecular:370.36Ro 24-4383
CAS:Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Fórmula:C32H31FN8O10S2Pureza:98%Cor e Forma:SolidPeso molecular:770.76BRL-42715
CAS:BRL-42715 is an effective inhibitor of bacterial beta-lactamases.Fórmula:C10H7N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:286.24Antifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Fórmula:C8H12N2S2Cor e Forma:SolidPeso molecular:200.32LasR-IN-1
LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.Fórmula:C23H21N3O2Cor e Forma:SolidPeso molecular:371.43Piperacillin hydrate
CAS:Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.Fórmula:C23H29N5O8SCor e Forma:SolidPeso molecular:535.57MsbA-IN-2
MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).Fórmula:C23H19Cl2NO3Cor e Forma:SolidPeso molecular:428.31RNAP-σ interaction inhibitor-2
CAS:RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Fórmula:C27H19Cl3N2O6S2Cor e Forma:SolidPeso molecular:637.939Anti-MRSA agent 3
CAS:Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.Fórmula:C29H18BrN3O2Cor e Forma:SolidPeso molecular:520.3861,5-Dideoxy-1,5-imino-D-mannitol
CAS:1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.Fórmula:C6H13NO4Cor e Forma:SolidPeso molecular:163.172LpxH-IN-2
CAS:LpxH-IN-2 (compound 014), a potent inhibitor of LpxH, exhibits antibacterial activity against E. coli.Fórmula:C27H33ClF2N6O4SCor e Forma:SolidPeso molecular:611.10CM-728
CAS:<p>CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.</p>Fórmula:C22H14N2O5Cor e Forma:SolidPeso molecular:386.35714α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C26H22N4O4Cor e Forma:SolidPeso molecular:454.48PCTR1
CAS:PCTR1, derived from DHA, hastens inflammation resolution and boosts macrophage function, reducing PGE2, PGD2, and TXB2 in mice.Fórmula:C32H47N3O9SCor e Forma:SolidPeso molecular:649.8D-CS319
CAS:D-CS319 is a potent inhibitor of metal-𝛽-lactamases (MBLs), exhibiting IC50 values of 2.0 μM for IMP-1 and 3.0 μM for IMP-78. RPX 7546 possesses antibacterial activity.Fórmula:C7H11NO2S3Cor e Forma:SolidPeso molecular:237.36DHFS-IN-1
CAS:DHFS-IN-1 (Compound 3) is an inhibitor of dihydrofolate synthetase (DHFS) with an IC50 of 2.6 μM. It is applicable for research into infectious diseases related to bacterial folate synthesis.Fórmula:C16H16N8O2Cor e Forma:SolidPeso molecular:352.35MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Fórmula:C16H16N4O5Cor e Forma:SolidPeso molecular:344.32FR-145715
CAS:FR-145715 is a histamine H2 receptor antagonist characterized by its specific anti-Helicobacter pylori activity. This compound is utilized in the study of gastric lesions.Fórmula:C16H21N5O2SCor e Forma:SolidPeso molecular:347.44(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Fórmula:C17H37N7O3Cor e Forma:SolidPeso molecular:387.52DNA Gyrase-IN-16
CAS:<p>DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.</p>Fórmula:C17H15N3O3Cor e Forma:SolidPeso molecular:309.319Carbonic anhydrase inhibitor 28
Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.Fórmula:C24H24FN5O7SCor e Forma:SolidPeso molecular:545.54MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Fórmula:C15H13N3O4SCor e Forma:SolidPeso molecular:331.35Rf470 TFA
CAS:Rf470 (Rotor NO.4) TFA is an FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently integrated into bacterial peptidoglycan. In its free state, Rf470 TFA exhibits weak fluorescence, which significantly increases upon integration into peptidoglycan by transpeptidase catalysis. This fluorescence change allows Rf470 TFA to be used for real-time monitoring of peptidoglycan biosynthesis, detecting transpeptidase activity, and screening antibiotics.Fórmula:C28H31F3N4O7SCor e Forma:SolidPeso molecular:624.63NBTI 5463
CAS:NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.Fórmula:C25H30N6O4Cor e Forma:SolidPeso molecular:478.54Aquayamycin
CAS:Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..Fórmula:C25H26O10Cor e Forma:SolidPeso molecular:486.47Penethamate hydriodide
CAS:Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.Fórmula:C22H32IN3O4SCor e Forma:SolidPeso molecular:561.477Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Fórmula:C23H24N6OCor e Forma:SolidPeso molecular:400.48L-threo-β-Hydroxyaspartic acid
CAS:L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic with activity against Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei, and Botrytis cinerea.Fórmula:C4H7NO5Cor e Forma:SolidPeso molecular:149.102MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Peso molecular:373.18Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Fórmula:C10H8BFO4Pureza:98%Cor e Forma:SolidPeso molecular:221.98HC2210
CAS:HC2210 exhibits antibacterial effects against Mycobacterium abscessus (Mab) with an EC50 of 0.72 µM. It modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is applicable for studies on Mab infections.Fórmula:C17H18N4O9Cor e Forma:SolidPeso molecular:422.35DL-2-Aminopimelic Acid
CAS:DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.Fórmula:C7H13NO4Cor e Forma:SolidPeso molecular:175.18Streptothricin F
CAS:Streptothricin F is a biochemical.Fórmula:C19H34N8O8Cor e Forma:SolidPeso molecular:502.52Nitrovin
CAS:Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.Fórmula:C14H12N6O6Cor e Forma:SolidPeso molecular:360.28BWC0977
CAS:BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.Fórmula:C22H21FN6O5Cor e Forma:SolidPeso molecular:468.44TAN-1057C
CAS:TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4MBX-1162
CAS:MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.Fórmula:C30H28N6Cor e Forma:SolidPeso molecular:472.58Antitubercular agent-23
Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).Fórmula:C20H22FN5O8SCor e Forma:SolidPeso molecular:511.48Ibafloxacine
CAS:Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect againstFórmula:C15H14FNO3Pureza:97.67%Cor e Forma:SolidPeso molecular:275.27Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Fórmula:C12H15N5O9S2Pureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:437.41Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Fórmula:C27H33Cl2FN4O8Pureza:95% - 99.68%Cor e Forma:SolidPeso molecular:631.48Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Fórmula:C25H36N6O8SPureza:99.85%Cor e Forma:SolidPeso molecular:580.65LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94
