Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3321 produtos de "Antibacteriano"
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LasR-IN-1
LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.Fórmula:C23H21N3O2Cor e Forma:SolidPeso molecular:371.43InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23Antibacterial agent 78
Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].Fórmula:C16H23N3S2Cor e Forma:SolidPeso molecular:321.5Bafilomycin C1
CAS:vacuolar H+-ATPases (V-ATPases) inhibitorFórmula:C39H60O12Pureza:98%Cor e Forma:Light Tan SolidPeso molecular:720.89JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.278-Hydroxyerythromycin A
CAS:8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.Fórmula:C37H67NO14Cor e Forma:SolidPeso molecular:749.926Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Fórmula:C19H24N2O4Cor e Forma:SolidPeso molecular:344.4Finafloxacin
CAS:Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.Fórmula:C20H19FN4O4Cor e Forma:SolidPeso molecular:398.39RNAP-σ interaction inhibitor-1
CAS:RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.Fórmula:C19H11Cl3N2O6S2Cor e Forma:SolidPeso molecular:533.79WQ3810
CAS:WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.Fórmula:C22H22F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:461.44Antibacterial agent 79
Antibacterial agent 79 is an antibacterial agent.Fórmula:C18H27N3O2S3Cor e Forma:SolidPeso molecular:413.62PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.898-Deazafolic acid
CAS:8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Fórmula:C20H20N6O6Pureza:98%Cor e Forma:SolidPeso molecular:440.41Levofloxacin mesylate
CAS:Levofloxacin mesylate is an orally active antibiotic effective against both Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase and topoisomerase IV enzymes. Levofloxacin mesylate is employed in research related to chronic periodontitis, airway inflammation, and BK viremia. Additionally, it possesses anti-Orthopoxvirus activity.Fórmula:C19H24FN3O7SCor e Forma:SolidPeso molecular:457.473PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Fórmula:C17H18ClN3OSCor e Forma:SolidPeso molecular:347.86MBL-IN-5
CAS:MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Fórmula:C20H16ClNO3Cor e Forma:SolidPeso molecular:353.80NBTIs-IN-4
NBTIs-IN-4, a broad-spectrum Gram-positive antibacterial, inhibits DNA rotamases/topoisomerase IV, with low resistance.Fórmula:C22H24FN5O5SCor e Forma:SolidPeso molecular:489.52MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Fórmula:C23H18Cl2FNO3Cor e Forma:SolidPeso molecular:446.3H052
CAS:<p>H052 is a selective inhibitor of Staphylococcus aureus α-hemolysin (Hla). It binds to the Hla monomer, disrupting its interaction with the host cell membrane, thereby blocking pore formation and inhibiting calcium influx, cytotoxicity, and inflammatory response. H052 exhibits inhibitory activity against Hla-induced calcium influx (EC50 = 30 nM in U937 cells) and holds potential for research into lung infections caused by S. aureus.</p>Fórmula:C21H15ClFN3O4SCor e Forma:SolidPeso molecular:459.88ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Fórmula:C31H35F3N4O3Cor e Forma:SolidPeso molecular:568.63AAA-10 formic
AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.Fórmula:C26H43FO7SCor e Forma:SolidPeso molecular:518.68(E)-Cefodizime
CAS:(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.Fórmula:C20H20N6O7S4Cor e Forma:SolidPeso molecular:584.669Bilanafos
CAS:Bilanafos is an agent of Anti-Bacterial.Fórmula:C11H22N3O6PPureza:98%Cor e Forma:SolidPeso molecular:323.28OSUAB-0284
CAS:OSUAB-0284 is an inhibitor of bacterial topoisomerase. It exhibits significant activity against staphylococci, particularly methicillin-resistant Staphylococcus aureus (MRSA). The compound exerts its antibacterial effect by inhibiting bacterial topoisomerase and may be used in research on infections caused by drug-resistant bacteria, including MRSA.Fórmula:C22H23FN6O6Cor e Forma:SolidPeso molecular:486.45Antibacterial agent 278
CAS:Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.Fórmula:C24H17ClF2N4O3Cor e Forma:SolidPeso molecular:482.87Nitrovin
CAS:Nitrovin is an antimicrobial growth promoter that induces ROS-mediated non-apoptotic and quasi-apoptotic cell death by targeting TrxR1. It exhibits anticancer activity with IC50 values ranging from 1.31 to 6.60 μM for both tumor and normal cells.Fórmula:C14H12N6O6Cor e Forma:SolidPeso molecular:360.28Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Fórmula:C24H28FN5O8Cor e Forma:SolidPeso molecular:533.51Antitubercular agent-15
Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.Fórmula:C21H29FN2Cor e Forma:SolidPeso molecular:328.47FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Fórmula:C21H16ClF2NO2Cor e Forma:SolidPeso molecular:387.81FG-2101
CAS:FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.Fórmula:C30H32N5O6PCor e Forma:SolidPeso molecular:589.579Antitubercular agent-29
Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.Fórmula:C20H12ClN3O5Cor e Forma:SolidPeso molecular:409.78Eravacycline dihydrochloride
CAS:Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Fórmula:C27H33Cl2FN4O8Pureza:95% - 99.68%Cor e Forma:SolidPeso molecular:631.48Gepotidacin mesylate dihydrate
CAS:Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Fórmula:C25H36N6O8SPureza:99.85%Cor e Forma:SolidPeso molecular:580.65Tigemonam
CAS:Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Fórmula:C12H15N5O9S2Pureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:437.41LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46Bicyclomycin benzoate
CAS:Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Fórmula:C19H22N2O8Cor e Forma:SolidPeso molecular:406.39α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.252-Mercaptopyridine N-oxide sodium
CAS:2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14Phosalacine
CAS:Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.367Zabofloxacin hydrochloride
CAS:Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Fórmula:C19H21ClFN5O4Pureza:98%Cor e Forma:SolidPeso molecular:437.86l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Dusquetide
CAS:Dusquetide is a first-in-class innate defense regulator. Dusquetide displays activity in both reducing inflammation and increasing the clearance of bacterial infection.Fórmula:C25H47N9O5Pureza:98%Cor e Forma:SolidPeso molecular:553.709N-Butylthiophosphoric triamide
CAS:N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.21Ciprofloxacin lactate
CAS:Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Fórmula:C20H24FN3O6Cor e Forma:SolidPeso molecular:421.43Pulcherriminic acid
CAS:Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Fórmula:C18H26OCor e Forma:SolidPeso molecular:258.4Cefetamet pivoxyl
CAS:Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].Fórmula:C20H25N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:511.571-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.Fórmula:C14H11F2NO4Cor e Forma:SolidPeso molecular:295.2382
