Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3260 produtos de "Antibacteriano"
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Antibiofilm agent-14
CAS:<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Fórmula:C26H30ClN3OCor e Forma:SolidPeso molecular:435.989Cefempidone
CAS:Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.Fórmula:C22H21N7O6S2Peso molecular:543.58Pks13-TE inhibitor 4
CAS:Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.Fórmula:C26H25N5O6Peso molecular:503.51Enzyme-IN-3 disodium
CAS:Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.Fórmula:C20H13N3Na2O8S2Cor e Forma:SolidPeso molecular:533.442Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Fórmula:C16H35N3O2Cor e Forma:SolidPeso molecular:301.47Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Fórmula:C19H25Cl2N5O3Cor e Forma:SolidPeso molecular:442.34Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Fórmula:C24H28FN5O8Cor e Forma:SolidPeso molecular:533.51MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Fórmula:C22H24N4O3Cor e Forma:SolidPeso molecular:392.45FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Fórmula:C21H16ClF2NO2Cor e Forma:SolidPeso molecular:387.81Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Fórmula:C20H18N2OCor e Forma:SolidPeso molecular:302.37PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Fórmula:C22H29N5O2Cor e Forma:SolidPeso molecular:395.5(1R,2S,7R)-Sitafloxacin
CAS:<p>(R)-Sitafloxacin (DU-6857) is an enantiomer of Sitafloxacin (DU-6859a) and functions as a topoisomerase inhibitor, demonstrating an IC50 of 0.18 μg/mL against DNA gyrase.</p>Fórmula:C19H18ClF2N3O3Cor e Forma:SolidPeso molecular:409.814QPX7728 bis-acetoxy methyl ester
CAS:QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Fórmula:C15H14BFO8Pureza:98%Cor e Forma:SolidPeso molecular:352.08Antimicrobial agent-29
CAS:Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].Fórmula:C19H14N4O4SCor e Forma:SolidPeso molecular:394.4Aeroplysinin 1
CAS:Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation.Fórmula:C9H9Br2NO3Cor e Forma:SolidPeso molecular:338.98Kalafungin
CAS:Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Fórmula:C16H12O6Cor e Forma:SolidPeso molecular:300.26Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Fórmula:C14H11N3O4SCor e Forma:SolidPeso molecular:317.32VEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.4Gepotidacin hydrochloride
CAS:Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Fórmula:C24H29ClN6O3Cor e Forma:SolidPeso molecular:484.98LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Cor e Forma:SolidPeso molecular:452.44
