Antibacteriano
Os inibidores antibacterianos são compostos que visam as células bacterianas, inibindo seu crescimento ou matando-as diretamente. Esses inibidores são essenciais no desenvolvimento de tratamentos para infecções bacterianas e são amplamente utilizados na pesquisa para estudar a fisiologia bacteriana, os mecanismos de resistência e a eficácia de novos agentes antibacterianos. Na CymitQuimica, oferecemos uma variedade de inibidores antibacterianos para apoiar sua pesquisa em microbiologia, doenças infecciosas e desenvolvimento de medicamentos.
Foram encontrados 3254 produtos de "Antibacteriano"
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Tuberculosis inhibitor 4
TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.Fórmula:C23H26N2O3SCor e Forma:SolidPeso molecular:410.537-Hydroxytropolone
CAS:7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.Fórmula:C7H6O3Cor e Forma:SolidPeso molecular:138.12Antibacterial agent 63
CAS:Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to aFórmula:C35H43N9O14S2Cor e Forma:SolidPeso molecular:877.9DNA gyrase B-IN-1
DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.Fórmula:C23H18ClF3N6O4SCor e Forma:SolidPeso molecular:566.94Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Fórmula:C7H14N3NaO8SCor e Forma:SolidPeso molecular:323.26Cefamandole lithium
CAS:Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.Fórmula:C18H17LiN6O5S2Cor e Forma:SolidPeso molecular:468.44(1S,2R,7S)-Sitafloxacin
CAS:(1S,2R,7S)-Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin and functions as a topoisomerase inhibitor. As an antibiotic, it demonstrates inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S)-Sitafloxacin exhibits antibacterial properties and is utilized in the study of various bacterial infections.Fórmula:C19H18ClF2N3O3Cor e Forma:SolidPeso molecular:409.81PF 03709270
CAS:PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Fórmula:C19H27NO7S3Pureza:98%Cor e Forma:SolidPeso molecular:477.61Antibacterial agent 110
Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).Fórmula:C22H21N5O4SCor e Forma:SolidPeso molecular:451.5Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Fórmula:C31H35F3N4O3Cor e Forma:SolidPeso molecular:568.63MtTMPK-IN-2
CAS:MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).Fórmula:C23H24ClN3O3Cor e Forma:SolidPeso molecular:425.91Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Fórmula:C30H35NO11Cor e Forma:SolidPeso molecular:585.60Antitubercular agent-22
Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).Fórmula:C24H28FN5O8Cor e Forma:SolidPeso molecular:533.51InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27Colistin adjuvant-1
Colistin adjuvant-1, inhibits NF-κB (IC50: 0.209 μM), boosts mucin against gram-negative bacteria.Fórmula:C16H7F9N2OCor e Forma:SolidPeso molecular:414.23FtsZ-IN-4
FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).Fórmula:C21H16ClF2NO2Cor e Forma:SolidPeso molecular:387.81QPX7728 bis-acetoxy methyl ester
CAS:QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.Fórmula:C15H14BFO8Pureza:98%Cor e Forma:SolidPeso molecular:352.08Anticancer agent 36
Compound 11: Sulfonylurea derivative, antimicrobial, anticancer; MIC 0.039-0.156 mg/mL; A549 IC50: 19.7 μg/mL, PC3 IC50: 11.9 μg/mL.Fórmula:C21H17N3O3S2Cor e Forma:SolidPeso molecular:423.51
