HBV
Os inibidores do HBV são compostos projetados para atingir e inibir várias etapas do ciclo de vida do vírus da hepatite B (HBV). Esses inibidores podem interferir na replicação, montagem ou liberação viral, reduzindo assim a carga viral e ajudando a gerenciar infecções crônicas por HBV. A pesquisa sobre inibidores do HBV é crucial para o desenvolvimento de terapias antivirais eficazes para prevenir doenças hepáticas e câncer associados ao HBV. Na CymitQuimica, oferecemos uma variedade de inibidores do HBV para apoiar sua pesquisa em virologia, desenvolvimento de medicamentos antivirais e controle de doenças infecciosas.
Foram encontrados 176 produtos de "HBV"
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HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Fórmula:C28H27BrF3N5O3Cor e Forma:SolidPeso molecular:618.44SAG-524
CAS:<p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>Fórmula:C30H32ClN5O4SCor e Forma:SolidPeso molecular:594.12HBV/HDV-IN-2
CAS:<p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>Fórmula:C38H44ClN7O5Cor e Forma:SolidPeso molecular:714.25TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Fórmula:C28H27N5O5SCor e Forma:SolidPeso molecular:545.61HBV-IN-12
CAS:<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Fórmula:C23H27NO8Cor e Forma:SolidPeso molecular:445.46HBV-IN-11
CAS:<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Fórmula:C21H24ClNO6Cor e Forma:SolidPeso molecular:421.87HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Fórmula:C17H15F6N5O2Cor e Forma:SolidPeso molecular:435.32HBV-IN-48
CAS:<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Fórmula:C22H15F4N3O3Cor e Forma:SolidPeso molecular:445.37FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Fórmula:C9H11FN6Na3O13P3Cor e Forma:SolidPeso molecular:592.11HBV-IN-31
CAS:<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Fórmula:C23H18ClNO6Cor e Forma:SolidPeso molecular:439.85HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Cor e Forma:SolidALG-000184
CAS:<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Fórmula:C23H20FN4Na2O8PCor e Forma:SolidPeso molecular:576.379HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Fórmula:C26H31F3N2O8Cor e Forma:SolidPeso molecular:556.53HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Cor e Forma:SolidPeso molecular:407.42Ref: TM-T79469
Produto descontinuadoHBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Fórmula:C18H16F3N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:487.48Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Fórmula:C29H28ClFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:563.02Ref: TM-T78756
Produto descontinuado
