Vírus da Influenza
Os inibidores do vírus da gripe são compostos que interferem na replicação e disseminação dos vírus da gripe. Esses inibidores são essenciais para pesquisar estratégias antivirais, compreender o ciclo de vida do vírus da gripe e desenvolver tratamentos e vacinas eficazes. Os inibidores da gripe podem atuar em várias etapas do processo de replicação viral, incluindo a entrada viral, replicação e liberação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do vírus da gripe para apoiar sua pesquisa em virologia, doenças infecciosas e desenvolvimento de medicamentos antivirais.
Foram encontrados 301 produtos de "Vírus da Influenza"
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Cap-dependent endonuclease-IN-17
CAS:CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.Fórmula:C24H20F2N3O7PSCor e Forma:SolidPeso molecular:563.47UNC0638 hydrate
CAS:UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.Fórmula:C30H49N5O3Cor e Forma:SolidPeso molecular:527.74Laninamivir trifluoroacetate
CAS:Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.Fórmula:C15H23F3N4O9Pureza:98%Cor e Forma:SolidPeso molecular:460.363Neuraminidase-IN-18
CAS:Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].Fórmula:C22H18FN3O3SCor e Forma:SolidPeso molecular:423.46AV-5080
CAS:AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.Fórmula:C15H25FN4O4Cor e Forma:SolidPeso molecular:344.38VV261
CAS:VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.Fórmula:C28H34FN3O11Cor e Forma:SolidPeso molecular:607.58Cap-dependent endonuclease-IN-5
CAS:Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Fórmula:C27H21F2N3O4S2Cor e Forma:SolidPeso molecular:553.60cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Fórmula:C16H22ClNOSCor e Forma:SolidPeso molecular:311.87Cap-dependent endonuclease-IN-10
CAS:Cap-dependent endonuclease-IN-10, with low toxicity & good stability, effectively inhibits flu viruses and shows promise against A, B, C types.Fórmula:C25H18F2N4O5SCor e Forma:SolidPeso molecular:524.50Cap-dependent endonuclease-IN-2
Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.Fórmula:C30H24FN3O7SCor e Forma:SolidPeso molecular:589.59RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.14Cap-dependent endonuclease-IN-6
CAS:Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Fórmula:C23H21N3O3SCor e Forma:SolidPeso molecular:419.5trans-RdRP-IN-5
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43Cap-dependent endonuclease-IN-7
CAS:Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.Fórmula:C36H28FN3O7SCor e Forma:SolidPeso molecular:665.69Cap-dependent endonuclease-IN-14
CAS:Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).Fórmula:C30H23FN2O6SCor e Forma:SolidPeso molecular:558.58Cap-dependent endonuclease-IN-25
CAS:Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Cap-dependent endonuclease-IN-1
CAS:Cap-dependent endonuclease-IN-1: potent, oral inhibitor with antiviral properties against influenza.Fórmula:C27H22F2N2O6SPureza:99.53% - 99.61%Cor e Forma:SolidPeso molecular:540.54UH15-38
CAS:UH15-38 is a potent and selective RIPK3 inhibitor that blocks necroptosis in alveolar epithelial cells triggered by IAV, useful for studying lung inflammation.Fórmula:C26H27N5O2Pureza:99.85%Cor e Forma:SolidPeso molecular:441.53FGI-106 tetrahydrochloride
CAS:FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as EbolaFórmula:C28H42Cl4N6Pureza:99.68%Cor e Forma:SolidPeso molecular:604.48
