Vírus da Influenza
Os inibidores do vírus da gripe são compostos que interferem na replicação e disseminação dos vírus da gripe. Esses inibidores são essenciais para pesquisar estratégias antivirais, compreender o ciclo de vida do vírus da gripe e desenvolver tratamentos e vacinas eficazes. Os inibidores da gripe podem atuar em várias etapas do processo de replicação viral, incluindo a entrada viral, replicação e liberação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do vírus da gripe para apoiar sua pesquisa em virologia, doenças infecciosas e desenvolvimento de medicamentos antivirais.
Foram encontrados 307 produtos para "Vírus da Influenza".
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Cap-dependent endonuclease-IN-25
CAS:Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48JNJ4796
CAS:JNJ4796 is an oral fusion inhibitor that neutralizes influenza A group 1 by blocking HA-mediated fusion, mimicking bnAbs.Fórmula:C28H27N9O3Pureza:98%Cor e Forma:SolidPeso molecular:537.57Massarilactone H
CAS:Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 µM .Fórmula:C11H12O5Cor e Forma:SolidPeso molecular:224.21Flutimide
CAS:Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28Saussureamine C
CAS:Saussureamine C is an inhibitor of H274Y and N294S mutants.Fórmula:C19H26N2O5Cor e Forma:SolidPeso molecular:362.42Neuraminidase-IN-11
Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.Cor e Forma:SolidCarbodine
CAS:Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.Fórmula:C10H15N3O4Pureza:98%Cor e Forma:SolidPeso molecular:241.24Cap-dependent endonuclease-IN-17
CAS:CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.Fórmula:C24H20F2N3O7PSCor e Forma:SolidPeso molecular:563.47Neuraminidase-IN-4
Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.Fórmula:C21H20N2O6SCor e Forma:SolidPeso molecular:428.46Laninamivir trifluoroacetate
CAS:Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.Fórmula:C15H23F3N4O9Pureza:98%Cor e Forma:SolidPeso molecular:460.363AV-5080
CAS:AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.Fórmula:C15H25FN4O4Cor e Forma:SolidPeso molecular:344.38Neuraminidase-IN-18
CAS:Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].Fórmula:C22H18FN3O3SCor e Forma:SolidPeso molecular:423.46Cap-dependent endonuclease-IN-5
CAS:Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Fórmula:C27H21F2N3O4S2Cor e Forma:SolidPeso molecular:553.60cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Fórmula:C16H22ClNOSCor e Forma:SolidPeso molecular:311.87Cap-dependent endonuclease-IN-10
CAS:Cap-dependent endonuclease-IN-10, with low toxicity & good stability, effectively inhibits flu viruses and shows promise against A, B, C types.Fórmula:C25H18F2N4O5SCor e Forma:SolidPeso molecular:524.50L-742001 Hydrochloride
CAS:L-742001 Hydrochloride is an RNA polymerase inhibitor.Fórmula:C23H25Cl2NO4Cor e Forma:SolidPeso molecular:450.355Cap-dependent endonuclease-IN-2
Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.Fórmula:C30H24FN3O7SCor e Forma:SolidPeso molecular:589.59RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.14Cap-dependent endonuclease-IN-6
CAS:Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Fórmula:C23H21N3O3SCor e Forma:SolidPeso molecular:419.5
