Oligossacarídeos

<p>Globotriose conjugated to HSA via an aminophenylethyl spacer (APE)</p>

4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose is a disaccharide. The lacto-n-biose unit is a nonreducing sugar that contains an alpha, beta unsaturated 1,6 glycosidic bond and a lactose molecule. 4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose has been found to stimulate the synthesis of galectin in vitro, which may be due to its ability to bind to lectins. This disaccharide can also cause denaturation at high temperatures.

<p>This is a synthetic sugar that can be used for glycosylation, oligosaccharides, and saccharides. It has been modified with fluorination, methylation, and click chemistry. This product is available in custom synthesis upon request.</p>

<p>3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranose (TFP) is a fluorinated carbohydrate synthesized by the reaction of 3,4,6 trihydroxyacetophenone with 2,3,4 trihydroxypentanediol and acetyl chloride. TFP is a complex carbohydrate that can be used to modify proteins and glycoproteins. The methylation of TFP has been shown to decrease the binding affinity between lectins and glycoproteins.</p>

<p>Lacto-N-fucopentaose III-APD-HSA is a custom synthesis, complex carbohydrate that has been modified with methylation and glycosylation. It is an oligosaccharide that is found in human serum albumin. Lacto-N-fucopentaose III-APD-HSA has been shown to have antitumor activity. It also inhibits the growth of bacteria by binding to bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. This compound binds to two sites on the 16S ribosomal RNA of bacteria and can inhibit protein synthesis, leading to cell death by inhibiting production of proteins vital for cell division. Lacto-N-fucopentaose III-APD-HSA has undergone fluorination and click modification.<br>Methylation: A process whereby a methyl group (-CH3) is added to an organic molecule via a chemical</p>

<p>1,3-α-D-mannopyranosyl trichloroacetimidate (1,3-α-DMTCA) is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. The synthesis of 1,3-α-DMTCA involves the reaction of α,β-unsaturated chloral hydrate with mannose in aqueous solution. This produces an intermediate product that undergoes glycosylation with glycosylation reagents like glycosyl chloride to yield 1,3-α-DMTCA. The chemical structure of 1,3-α-DMTCA can be modified by various reactions including methylation or click modification. 1,3 DMTCA is also available as a high purity material.<br>1,3 α - D - mannosyltetrahydrochlorofonuimidoksyl</p>

<p>Oroxylum indicum is a plant that belongs to the family Bignoniaceae. It has been used in traditional medicine for the treatment of cancer and has been shown to possess anti-inflammatory properties. The sequenced genome of Oroxylum indicum has provided a model system for understanding the molecular mechanisms underlying tumorigenesis. This plant contains a number of monoclonal antibodies, including one that is active against mouse monoclonal antibodies and inhibits tumor xenografts. The extract of this plant also inhibits influenza virus and polymerase chain reactions, which are important steps in protein synthesis. Oroxylum indicum may have therapeutic potential as an anti-cancer drug because it can inhibit solid tumours by interfering with protein synthesis.</p>

<p>A di-acetamido LacNAc analogue</p>

<p>O-(Methyl b-d-glucopyranosyluronate)-(1,3)-2-amino-2-deoxy-D-galactopyranose HCl is a synthetic monosaccharide with a molecular weight of 338.18 g/mol. It has very high purity and can be custom synthesized to suit customer needs. This product is used in glycosylation reactions and as a sugar donor in click chemistry reactions.</p>

<p>N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside is a galactosyltransferase inhibitor. It prevents the enzymatic transfer of a sugar group from UDP-galactose to an acceptor molecule by binding to the enzyme. N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside inhibits the enzymatic galactosylation of glycoproteins in cells and has been shown to be effective against bacterial strains resistant to other antibiotics. This drug is also chemoenzymatically synthesized using enzymes and chemical reagents.</p>

<p>6-O-Benzoyl-1,2,3-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-a -D-galactopyranosyl)-b -D -galactopyranoside is an oligosaccharide that has been custom synthesized by our company. It is a complex carbohydrate with a molecular weight of 1,216. The CAS number for this product is 105838-36-5. This product also has a high degree of purity and can be used in Click modification and Modification reactions. 6 O Benzoyl 1 2 3 tri O benzyl 4 O</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactofuranosyl)-D-glucopyranose is a carbohydrate that belongs to the class of disaccharides. It is a member of the family of b-D-galactofuranosides, which are derived from the hydrolysis of glycosidic linkages in b-D-galactopyranose. 2A2DDG has been shown to interact with sulfate groups and nonreducing sugars. The interaction between 2A2DDG and sulfate groups may be due to the presence of hydroxyl group on the molecule's side chain. The disaccharide can be used as an analogue for glycosylation experiments, such as those involving glycosyltransferases or glycosidases.</p>

<p>Hyaluronate fluorescein is a synthetic, high purity complex carbohydrate with a molecular weight of 1500kDa. It is a modification of the naturally occurring polysaccharide hyaluronan. It is composed of repeating units of the monosaccharide D-glucuronic acid and the disaccharide N-acetyl-D-glucosamine. Hyaluronate fluorescein is synthesized by methylation and glycosylation of D-glucuronic acid, followed by fluorination to produce the fluorinated saccharide hexafluoro-D-glucuronic acid, which reacts with N-acetyl-D-glucosamine in an amidation reaction. The product can then be modified to produce hyaluronate fluorescein.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-benzyl-b-D-galactopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is made up of a saccharide and a sugar. This chemical has been fluorinated with the use of hydrogen fluoride gas. The chemical also has methyl groups that have been added to it. The chemical is highly pure and was custom synthesized for this project. This chemical can be used in glycosylation or click chemistry.</p>

<p>Hyaluronate biotin is a high purity and complex carbohydrate. It is synthesized by methylation, saccharide, polysaccharide, and glycosylation of natural hyaluronic acid. Hyaluronate biotin is a modified form of hyaluronic acid that contains an additional biotin molecule per every 500 kDa of molecular weight. This modification can be used in the development of new drugs or as a supplement to improve joint health.</p>

<p>This is a custom synthesis of 1,3,6-tri-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-azido-2-deoxy--aDglucopyranose. This product is a synthetic oligosaccharide that has been modified to contain fluorine atoms at the C1 and C6 positions. It has a CAS number of 5243787 and is available in high purity. It is also an Oligosaccharide and Polysaccharide.</p>

<p>4-O-b-(2,3,4,6-Tetra-O-acetyl-D-galactopyranosyl)-1,6-anhydro-2,3-O-isopropylidene-b-D-mannopyranose is a custom synthesis of a monosaccharide. This monosaccharide is synthesized by the fluorination and methylation of 4,6 anhydro b D mannose followed by the click modification of the hydroxyl groups. The chemical name for this monosaccharide is 1,6 anhydro 2,3 O isopropylidene b D mannopyranose. It has a molecular weight of 390. The CAS number for this monosaccharide is 5346 69 0. 4,6 anhydro b D mannose is found in polysaccharides such as glycosaminoglycans</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>2-Acetamido-4-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-1,6-di-O-[N-(acetylamino)glycoloyl]-D--muramic acid is a synthetic sugar that is used in biotechnology and pharmaceuticals. It is synthesized by the glycosylation of 2,3,4,6 - triacetyl b - D - glucopyranoside with 1,6 di - O - N - acetyl - D - muramic acid. 2 Acetamido 4 O (2 acetamido 2 deoxy 3 4 6 tri O acetyl b D glucopyranoside) 1 6 di O N acetyl D muramic acid has been shown to inhibit bacterial growth through methylation and modification of bacterial enzymes.</p>

<p>Lewis A trisaccharide methyl glycoside tetrabenzylether is a synthetic glycosylated oligosaccharide. It is a custom synthesis product that can be modified to the customer's specifications. The modification reaction yields a high-purity, complex carbohydrate with a saccharide content of 95%. This product is soluble in DMSO and DMF and is stable at pH 3-11.</p>