Compostos Policiclícos

<p>Applications 3-Azabicyclo[3.3.0]octane Hydrochloride is a reactant in the preparation of substituted pyrimidines derivatives as novel hedgehog signaling pathway inhibitors.<br>References Xin, M. et al.: Med. Chem. Res., 23, 3784 (2014); Xin, M. et al.: Bioorg. Med. Chem. Lett., 24, 983 (2014);<br></p>

<p>Applications 5,7-dihydroxy-4-methyl-2H-chromen-2-one (cas# 2107-76-8) is a useful research chemical.<br></p>

<p>Applications 7-Chloro-4-nitroquinoline is used in the synthesis of aminonitropyridine.<br></p>

<p>Applications (3S)-Aminoquinuclidine is an intermediate used in the synthesis of Palonosetron-3-ene Hydrochloride (P165825), which is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993); Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995); Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003); Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004); Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004)<br></p>

<p>Applications 8-Chloro-5-isoquinolinesulfonic Acid (cas# 1246816-17-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Benzyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid (cas# 54329-48-5) is a useful research chemical.<br></p>

<p>Applications Methyl-2-aminoquinoline-6-carboxylate is an organic building block of ester and amine category.<br>References Li, L., et al.: PCT Int. Appl. (2018), WO 2018196823 A1 20181101<br></p>

<p>Applications (2R,3aS,7aS)-Octahydroindole-2-carboxylic Acid Hydrochloride is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.<br>References Vincent, M., et al.: Drug Design Disc., 9, 11 (1992), Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)<br></p>

<p>Applications 3-Amino-3-benzyl-3,4-dihydroquinolin-2(1H)-one<br></p>

<p>Applications Methyl indoline-5-carboxylate<br></p>

<p>Applications XANTHENE-9-CARBOXAMIDE (cas# 5813-90-1) is a useful research chemical.<br></p>