Compostos Policiclícos

Applications 1H-Indole-d5-3-acetamide is the isotope labelled analogue of Indole-3-acetamide, a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.
References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010);

Applications 9-oxo-9H-Thioxanthene-4-carboxylic acid (cas# 51762-56-2) is a useful research chemical.

Applications 5-Hydroxyquinoline-3-carboxylic acid (cas# 911108-90-2) is a useful research chemical.

Applications 4,8-DICHLOROQUINOLINE (cas# 21617-12-9) is a useful research chemical.

Applications 2-Oxa-7-azaspiro[3.5]nonane is an intermediate used to prepare benzothienoazepine derivatives as potent respiratory syncytial virus RNA polymerase inhibitors. It is also used to prepare 1,7-Diazacarbazole derivatives as inhibitors of checkpoint kinase 1.
References Xiong, H., et al.: Bioorg. Med. Chem. Lett., 23, 6789 (2013); Gazzard, L., et al.: J. Med. Chem., 58, 5053 (2015)

Applications 3-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-3,4-dihydro-5H-imidazo[2,1-i]purine-5-thione is used in the synthesis of azidoetheno analogs of deoxyadenosine as nucleotide photo-affinity probes.
References Flaherty, D. et al.: Nucleos. Nucleot., 14, 65 (1995);

Stability Hygrscopic
Applications 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

Applications Methyl quinoline-4-carboxylate (cas# 21233-61-4) is a useful research chemical.

Applications Ethyl 4,6,8-trichloroquinoline-3-carboxylate

Applications 6-Fluoroquinoline, is a versatile building block used in the synthesis of various chemical compounds.

Applications 2,6-Dichloro-9-nitroso-9H-purine is a compound useful in organic synthesis.

Applications 4-Hydroxy-quinoline-6-carboxylic acid

Stability Hygroscopic
Applications 7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone is used in the synthesis of aripiprazole, an antipsychotic oral drug used in the treatment of Schizophrenia.
References Bonacorsi, S. et al.: J. Label. Comp. Radiopharm., 49, 1 (2006); Morita, Seiji; K. et al.: Tetrahedron, 54, 4811 (1998);

Applications tert-Butyl 1,6-Diazaspiro[3.4]octane-1-carboxylate is a reactant in the preparation of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors.
References Sippy, K.B., et. al.: Bioorg. Med. Chem. Lett., 19, 1682 (2009)

Applications 3-(quinolin-2-yl)propanoic acid (cas# 39111-94-9) is a useful research chemical for biological study. In particular it has been used in identifying structure-activity relationship of HDAC6 zinc-finger ubiquitin binding domain inhibitors.
References Ferreira, F., et al.: J. Med. Chem, 61, 4517 (2018)

Indole-3-acetyl-L-glutamic acid is an endogenous substance that is found in plants. It is the conjugated form of indole-3-acetaldehyde and L-glutamic acid. Indole-3-acetylglutamic acid has shown to have antioxidant potential and can be used to regulate plant growth, as well as protect against environmental stresses. Indole-3-acetylglutamic acid also has a role in regulating the production of other hormones, such as ethylene and auxin, which are involved in plant growth regulation.

Please enquire for more information about (3R)-1-Azabicyclo[2.2.2]oct-3-yl N-[2-(2-benzoylphenyl)ethyl]carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Hydroxyquinolin-2(1H)-one is a chalcone that can be synthesized from 2,5-dihydroxybenzaldehyde and quinoline. It is a bacteriostatic agent that inhibits bacterial growth by binding to the 50S ribosomal subunit, blocking the formation of an antibiotic-substrate complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. 5-Hydroxyquinolin-2(1H)-one has shown activity against methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistant Enterococcus faecium. 5-Hydroxyquinolin-2(1H)-one also represses the expression of DNA topoisomerase II genes, which may be associated with its inhibitory effects on bacterial growth.

Please enquire for more information about 4,7-Diazaspiro[2.5]octane dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,3-Dipropyl-7-methylxanthine is a xanthine compound that is structurally related to caffeine. It has been shown to have an inhibitory effect on the production of reactive oxygen species and cytosolic calcium levels in primary cells, as well as a nonselective adenosine receptor antagonist activity. It has also been shown to antagonize the effects of adenosine receptors, p2 receptors, and p2y receptors. This drug is used for the treatment of basophilic leukemia.

Please enquire for more information about 6-Bromo-4-nitro-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page