Compostos Policiclícos

<p>Benazeprilat is a prodrug that is metabolized to enalaprilat, its active form. It is an inhibitor of angiotensin-converting enzyme (ACE) and has been shown to be effective in the treatment of heart failure. It has also been shown to inhibit ACE activity in vitro and in experimental models of congestive heart failure. Benazeprilat binds to the active site on the ACE molecule and inhibits the conversion of angiotensin I into angiotensin II, which causes vasoconstriction and stimulates aldosterone release from the adrenal cortex. This drug also has effects on energy metabolism by stimulating beta oxidation, which leads to increased levels of ketone bodies in blood plasma.</p>

<p>4-Hydroxy-7-methoxyquinoline is an anti-malarial drug that belongs to the class of trimethyl, trifluoromethyl group. It is a cyclic compound and its synthesis starts with cyclization of the methyl derivative, which forms a ring. This product is used in clinical practice as an inhibitor of malarial protozoa and has been shown to have mechanistic effects on the cytochrome bc1 complex containing red blood cells. 4-Hydroxy-7-methoxyquinoline also inhibits the growth of bacteria by binding to the enzyme methionine synthase, which is involved in the biosynthesis of methionine from homocysteine. The product also has an inhibitory effect on DNA synthesis and protein synthesis.</p>

<p>Please enquire for more information about Ethyl5-acetyloxy-1,2-dimethylindole-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Bergapten is a naturally occurring furanocoumarin, which is derived from the essential oils of citrus fruits, such as bergamot. It is recognized for its photosensitizing properties due to its ability to interact with DNA upon exposure to ultraviolet (UV) light. The mode of action involves the formation of monoadducts with pyrimidine bases in DNA, which can lead to cross-linking and ultimately disrupt DNA replication and transcription.</p>

<p>Please enquire for more information about Calipteryxin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cinnoline is a chemical compound that is structurally similar to phenol, containing a hydroxyl group, two nitrogen atoms and a cyclic structure. Cinnoline has been shown to have anti-inflammatory activity in rats with adjuvant-induced arthritis. The mechanism of the anti-inflammatory effect of cinnoline is not fully understood, but it may be due to its stability and ability to bind to biological molecules or its conformational properties. Cinnoline does not react with nitric acid, making it a good candidate for use in infectious diseases such as tuberculosis. It has also been shown to be stable in human serum and has low pharmacokinetic properties. The fluorescence intensity of cinnoline was found to increase when exposed to an electrochemical potential and can be used as a probe molecule for pharmacokinetics studies.</p>

<p>2,4-Dioxo-9-(phenylmethyl)-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile is an aliphatic compound that is used in the synthesis of formaldehyde and amines. It has been shown to react with formaldehyde to produce a mixture of aliphatic amines. This reaction can be used for the production of commercial products such as dyes and pharmaceuticals.</p>

<p>1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid monomethyl ester is a chemical compound used in research and as a building block for complex compounds. It is a high quality and versatile compound that has a wide range of uses in the production of fine chemicals. This compound is an intermediate for the synthesis of 1,4-benzodioxan. CAS No. 83249-10-9</p>

Please enquire for more information about 2-Amino-3-(1.2-dihydro-2-oxoquinoline-4-yl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Murrangetin is a flavonoid compound, which is a natural phytochemical sourced from the peels of various citrus fruits. Its mode of action primarily involves the modulation of inflammatory pathways, potentially through the inhibition of specific enzymes like cyclooxygenases and lipoxygenases. This flavonoid is also known for its antioxidative properties, which contribute to its ability to scavenge free radicals, thereby reducing oxidative stress in biological systems.</p>

<p>Please enquire for more information about Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 6-bromo-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ostruthin is a naturally occurring coumarin derivative, which is isolated from plants such as *Peucedanum ostruthium* and other species within the Apiaceae family. It functions as an enzyme inhibitor, acting primarily through its interference with various cellular processes, including the inhibition of specific enzyme pathways that contribute to its bioactivity. Ostruthin exhibits a range of biological activities, making it of significant interest in pharmacological research.</p>

<p>7-Azaindole-5-carboxylic acid methyl ester is an ester derivative that can be synthesized from the reaction of acetyl chloride and diazotization. 7-Azaindole-5-carboxylic acid methyl ester has been used in research for its biological activity, specifically as a cytotoxic agent. It has also been shown to inhibit the growth of cancer cells by alkylation reactions and cyclization reactions. 7-Azaindole-5-carboxylic acid methyl ester has been shown to have antitumor properties with a mechanism that is not yet fully understood.</p>

<p>8-Bromo-2-methylquinoline is a naphthalene derivative that has an oxidant function. It can be used as a solvent for chlorobenzene and as a catalyst for the production of bipyridines and piperazine. 8-Bromo-2-methylquinoline is also used as a ligand in the preparation of metal complexes. This compound reacts with methyl groups, chlorine, and halides to form methyl quinolines and dichloromethanes. 8-Bromo-2-methylquinoline may react with fatty acids to form polyunsaturated acid esters or with polyunsaturated fatty acids to form polyethers.</p>

<p>Please enquire for more information about L-(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid benzyl ester tosylate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Anomelin is a synthetic anticancer compound, which is derived from complex organic synthesis methodologies. This compound is typically produced through careful laboratory processes due to its intricate chemical structure, which is crafted to target specific molecular pathways involved in cancer cell proliferation.</p>

<p>5,6-Dimethoxy-1H-indazole is a phosphite that has been used as an intermediate in the synthesis of some pharmaceuticals. It has been shown to have hypotensive effects in rats and depressant effects in mice. The nitro group on 5,6-dimethoxy-1H-indazole can be reduced to an aminopropyl group by reaction with chloride and methyl alcohol or piperazine. This reaction produces two products: 1) a chloro compound that is not pharmacologically active and 2) a methylated product that retains all the original activity of 5,6-dimethoxy-1H-indazole. 5,6-Dimethoxy-1H-indazole also interacts with DNA by binding to nitrous oxide (N2O), which is present at high levels in clinical settings such as dentists' offices. Nitrous oxide reacts with 5,6-dimethoxy-1H</p>

<p>Imidazole is a highly polar aromatic compound with two annular nitrogen atoms. Imidazole is widely used in the affinity purification of proteins with polyhistidine tags (His-Tag). In the protein purification process, imidazole is used for the elution of His-Tag-fused recombinant proteins from a metal-immobilised resins. In the elution buffers, imidazole is typically used in the 50 – 500 mM concentration range (Bornhorst and Falke, 2000).</p>