
Ligas Organometálicas
Subcategorias de "Ligas Organometálicas"
- Ligantes de Buchwald(25 produtos)
- DPEN(4 produtos)
- DPHEN(4 produtos)
- JOSIPHOS(4 produtos)
- Fosfina(486 produtos)
- Porfirinas(73 produtos)
Foram encontrados 2868 produtos para "Ligas Organometálicas".
3-(4-Phenylbutyl)-4-propyloxetan-2-one
CAS:Cis/trans-form of GK 563 [2351820-19-2]Fórmula:C16H22O2Pureza:Min. 95%Cor e Forma:SolidPeso molecular:246.34 g/molFurosemide - Bio-X ™
CAS:Produto ControladoFurosemide is a potent loop diuretic that is used in the treatment of hypertension, liver cirrhosis, renal disease and heart failure. This drug acts on the kidney to increase water loss from the body. It inhibits electrolyte reabsorption. Furosemide also exerts vasodilatory effects.
Fórmula:C12H11ClN2O5SPureza:Min. 95%Cor e Forma:PowderPeso molecular:330.74 g/molCerivastatin sodium
CAS:An inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase that reduces total cholesterol and low-density lipoprotein (LDL). Cerivastatin is cardioprotective and anti-atherosclerotic. Cerivastatin inhibits the expression of the atherosclerotic genes monocyte chemoattractant protein-1 (MCP-1) and C-C chemokine receptor type 2 (CCR2), whilst inducing the expression of Kruppel-like factor 2 (KLF2).Fórmula:C26H33FNNaO5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:481.53 g/molIrbesartan - Bio-X ™
CAS:Irbesartan is an angiotensin II receptor antagonist that is used to treat hypertension and congestive heart failure. It is also used to delay the progression of diabetic nephropathy. This drug works to works to relax smooth muscles and lower blood pressure.Fórmula:C25H28N6OPureza:Min. 95%Cor e Forma:PowderPeso molecular:428.53 g/molR-(-)-Arundic acid
CAS:R-(-)-Arundic acid is a chiral compound, which is a derivative of arundic acid specifically designed for enantiomeric purity. It is sourced through synthetic organic chemistry processes, allowing for precise control over its stereochemistry. The mode of action of R-(-)-Arundic acid involves the inhibition of astrocyte activation by modulating the synthesis of certain cytokines and inflammatory mediators. This mechanism provides a neuroprotective effect, making it a valuable tool in the study of neurodegenerative diseases and brain injuries.
Fórmula:C11H22O2Pureza:Min. 98 Area-%Cor e Forma:Clear Viscous LiquidPeso molecular:186.29 g/molExifone
CAS:Mildly inhibits tau protein fibril formation; enhances cognitive functionFórmula:C13H10O7Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:278.21 g/molTetrabenazine - Bio-X ™
CAS:Produto ControladoTetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2). Tetrabenazine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use."Fórmula:C19H27NO3Pureza:Min. 99 Area-%Cor e Forma:White PowderPeso molecular:317.42 g/molMitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFórmula:C22H30Cl2N4O6Pureza:Min. 97 Area-%Cor e Forma:Dark Blue SolidPeso molecular:517.4 g/molSorafenib - Bio-X ™
CAS:Sorafenib is a drug that belongs to the class of multikinase inhibitors. It inhibits a number of kinases, including the Mcl-1 protein, which is involved in apoptosis along with blocking picolinic acid (PA), an endogenous metabolite involved in apoptosis signal transduction. Sorafenib also binds to epidermal growth factor receptor (EGFR) on the surface of cancer cells, inhibiting the production of proteins that are required for angiogenesis, thus blocking the formation of new blood vessels. Sorafenib may also inhibit P-glycoprotein (Pgp) activity. Overall, these cytotoxic effects give Sorafenib anti-tumor properties, inhibiting angiogenesis and cellular transformation, which are the two main processes of tumor growth and metastasis. Sorafenib has been shown to be effective against a range of solid tumors such as breast, prostate and lung cancers and is also used for the treatment of metastatic colorectal cancer and renal cell carcinoma. A combination therapy group found that sorafenib was more effective when used with interferon alfa-2b for the treatment of advanced renal cell carcinoma. Sorafenib also has the potential for drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Sorafenib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C21H16ClF3N4O3Pureza:Min. 98%Cor e Forma:PowderPeso molecular:464.82 g/molMLN 4924
CAS:MLN 4924 is a selective small molecule that acts as an inhibitor of the Nedd8-activating enzyme. This compound is synthetically derived and functions by inhibiting the conjugation of Nedd8 to cullin proteins. By blocking this pathway, MLN 4924 disrupts the activity of the SCF (Skp, Cullin, F-box containing complex) E3 ubiquitin ligase, leading to an accumulation of proteins that can induce apoptosis and cell cycle arrest.
Fórmula:C21H25N5O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:443.52 g/molPitolisant hydrochloride - Bio-X ™
CAS:Pitolisant is an inverse agonist and antagonist of the histamine (H3) receptor. It acts as an allosteric modulator of the H3 receptor to increase the activity of histamine at the M1 receptor. Pitolisant has been used in the treatment of narcolepsy, schizophrenia and Alzheimer's disease. Its mechanism of action involves binding to the amide group on histamine, which increases its affinity for the H3 receptor and enhances its activity at this site. Pitolisant has been shown to improve cognitive ability and reduce fatigue in patients with Alzheimer's disease. Pitolisant is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C17H26ClNO·HClPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:332.31 g/molES9-17
CAS:Inhibitor of clathrin-mediated endocytosis (CME) and ligand to the clathrin heavy chain (CHC). ES9-17 is an inhibitor of the CHC function with EC50 of 13 μM in plant model Arabidopsis thaliana. ES9-17 is a non-protonophoric CME inhibitor and it does not alter the cytoplasmic pH levels substantially. In a mammalian cell line HeLa, ES9-17 reduced the uptake of transferrin, which is a CME-driven process.
Fórmula:C10H8BrNO2S2Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:318.21 g/molPadsevonil
CAS:Padsevonil is an investigational antiseizure medication, which is a synthetic pharmaceutical compound. It is derived from extensive medicinal chemistry research aiming to address complex seizure disorders resistant to conventional treatments. Padsevonil functions by exhibiting a dual mechanism of action. It binds to synaptic vesicle protein 2A (SV2A) with high affinity, similar to levetiracetam but with additional modulation of the benzodiazepine-sensitive gamma-aminobutyric acid-A (GABA-A) receptor. This combined activity potentiates its efficacy in stabilizing neuronal hyperactivity and dampening excitatory neurotransmission, providing a novel angle to tackle refractory seizures.Fórmula:C14H14ClF5N4O2SPureza:Min. 95%Peso molecular:432.8 g/molDiacerein - Bio-X ™
CAS:Diacerein is a slow-onset anthraquinone IL-1 inhibitor that is used in the treatment of joint diseases such as osteoarthritis. This drug is also being studied for the treatment of insulin resistance and diabetes mellitus. Diacerein works to decrease inflammation and cartilage destruction by reducing the level of interleukin-1.Fórmula:C19H12O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:368.29 g/molToceranib phosphate - Bio-X ™
CAS:Produto ControladoToceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be effective in the treatment of skin cancer and other types of cancer, including lung cancer and breast cancer. It is approved in the US as a treatment for canine mastocytoma (mast cell tumours).Fórmula:C22H25FN4O2·H3O4PPureza:Min. 95%Cor e Forma:PowderPeso molecular:494.45 g/molEpacadostat
CAS:Inhibitor of dioxygenase IDO1Fórmula:C11H13BrFN7O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:438.23 g/molLacidipine - Bio-X ™
CAS:Lacidipine is a lipophilic dihydropyridine calcium channel blocker that is used in the treatment of hypertension. This drug acts as an antihypertensive agent to dilate peripheral arteries and reduces blood pressure. Lacidipine blocks voltage-dependent L-type calcium channels.Fórmula:C26H33NO6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:455.54 g/molCyamemazine
CAS:Cyamemazine is a neuroleptic medication, which is a member of the phenothiazine class of compounds. It is synthesized from derivatives of phenothiazine, a group of agents primarily found in pharmaceuticals. The mode of action of cyamemazine involves antagonism at dopamine D2 receptors in the central nervous system. This inhibition of dopamine activity is the principal mechanism through which it exerts its antipsychotic effects. Due to its receptor activity, cyamemazine is used primarily in the management of various psychotic disorders, including schizophrenia and acute psychoses. It also exhibits anxiolytic properties, making it effective in treating anxiety associated with these conditions. By modulating neurotransmitter pathways, cyamemazine helps to alleviate symptoms such as hallucinations, delusions, and agitation, offering therapeutic benefit in complex neuropsychiatric cases. As an atypical antipsychotic, it provides an option for patients who may not respond adequately to other treatments. Although primarily used in a clinical setting, ongoing research continues to investigate potential wider applications and efficacy in treating other mental health issues.Fórmula:C19H21N3SPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:323.46 g/molSEN 12333
CAS:Agonist of alpha7 subtype of nural nicotinic acetylcholine receptorFórmula:C20H25N3O2Pureza:Min. 95%Cor e Forma:SolidPeso molecular:339.43 g/molBDP 37
CAS:BDP 37 is a type of boron-dipyrromethene (BODIPY) dye, which is a class of fluorescent compounds known for their stability and brightness. These dyes are synthetic, designed for optimal photophysical properties, and are synthesized through the condensation of pyrrole derivatives with boron difluoride. BDP 37 operates by absorbing light and emitting fluorescence, a process facilitated by its delocalized electron system, which results in a high quantum yield and exceptional photostability. This makes it particularly well-suited for applications requiring long exposure to light.Fórmula:C13H13NO4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:247.08446
