Compostos de organossilícico

<p>Applications Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate is used in synthesis of 1-Alkynyl(triphenyl)arsonium Tetrafluoroborates by onium transfer reaction of 1-Alkynyl(phenyl)iodonium Tetrafluoroborates with Triphenylarsine. Also, used in preparation of Furan- and Thiophene-substituted alkynes and alkynyl ketones by Copper Iodide-catalyzed coupling and carbonylation of Heterocyclic Boronic Acids with Alkynyliodonium salts.<br>References Nagaoka, T., et al.: Tetrah. Lett., 36, 261-4 (1995); Yu, Chan-Mo, et al.: Synlett, 2631-2634 (2005);<br></p>

<p>Applications 2-tert-Butyldimethylsilyloxyethyl Tosylate is an intermediate in the synthesis of Everolimus (E945400), which is Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (3-Aminopropyl)trimethoxysilane is used in the synthesis of aspirin imprinted polymer on silica gel surface and appreciation on drug sustained release. Fluorine-doped; lectin functionalized ZnO nanoarrays as 3D nano-biointerface for bacterial detection.<br>References Lu, P., et al.: Gaofenzi Cailiao Kexue Yu Gongcheng, 33, 130 (2017); Zheng, L., Talanta, 167, 600 (2017)<br></p>

<p>Applications Furan-2-boronic acid<br></p>

<p>Applications Di(p-anisyl)iodonium Tetrafluoborate (cas# 1426-58-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-O-tert-Butyldimethylsilyl-cholest-5-ene-3-ol 24-(2-hydroxyisopropyl) 24-Phenyl Sulfinate is an intermediate in the preparation of Campesterol (C155360).<br></p>

<p>Applications Perphenylcyclopentasilane is an intermediate in the synthesis of Cyclopentasilane (C988380), a reagent used for depositing silicon on surfaces for electronics applications.<br>References Morisaki, Y., et al.: Chem. Lett., 38, 498 (2009);<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications 3-Formylphenylboronic Acid is a reactant in the synthesis of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gosmini, R., et. al.: J. Med. Chem., 57, 8111 (2014)<br></p>

<p>Applications 2-Cyclohexylvinylboronic Acid is used in the synthesis of vinylbenziodoxolones, a novel type of hypervalent iodine(III) reagents.<br>References Stridfeldt, E., et al.: Chem. Eur. J., 22, 16066-16070 (2016)<br></p>

<p>Applications Methylboronic Acid is a methylated derivative of boronic acid, a building block towards various intermediates in suzuki coupling.<br>References Baker, J. O., et al.: Biochem.. 22, 2098 (1983); Garner, C.W., et al.: J. Biol. Chem., 255, 5064 (1980)<br></p>

<p>Applications TETRAMETHYLAMMONIUM BOROHYDRIDE (cas# 16883-45-7) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Acetylphenylboronic acid4-Acetylphenylboronic Acid is used in several metal catalyzed cross-coupling reaction studies.<br>References Saito, S., et al.: J. Org. Chem., 2, 8024 (1997); Sakai, M., et al.: Organomet., 16, 4229 (1997); Molander, G., et al.: J. Org. Chem., 68, 4302 (2003);<br></p>

<p>Applications Ethynylboronic Acid MIDA Ester is a useful reagent in preparatino of borono-substited 1(2H)-isoquinolinones by rhodium-catalyzed cycloaddition.<br>References Wang, H., et al.: J. Am. Chem. Soc., 134, 19592 (2012);<br></p>

<p>Applications TRIMETHYL(BROMODIFLUOROMETHYL)SILANE (cas# 115262-01-6) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Chloroborane Methyl Sulfide Complex is a reagent in the synthesis of 3,4-Dimethyl-5-pentyl-2-furanundecanoic Acid (D477535); a furan fatty acid known to exhibit radical-scavenging ability and having anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Grahl, N., et al.: Marine. Biol., 157, 1567 (2010); Spiteller, G., et al.: Lipids., 40, 75 (2005); Wakimoto, T., et al.: PNSA., 108, 17533 (2011)<br></p>

<p>Applications Thiazol-4-ylboronic acid (cas# 1016642-07-1) is a useful research chemical.<br></p>

<p>Applications Benzothiophene-5-boronic acid<br></p>

<p>Impurity Paclitaxel - In House Impurity<br>Applications Protected Baccatin III. Paclitaxel - In House Impurity.<br></p>

<p>Applications Stigmasteryl-O-tert-butyldimethylsilane Ferulate is an intermediate used in the synthesis of Stigmasteryl Ferulate (S686768), which is used for purification and identification of components of γ-oryzanol in rice bran oil.<br>References Xu, Z., et al.: J. Agric. Food Chem., 47, 2724 (1999);<br></p>

<p>Applications methyl 4-(bromomethyl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas# 1626407-50-8) is a useful research chemical.<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Pinacol Ester could be useful for the diastereoselective synthesis of cyclic peptide macrocycles via Petasis borono-Mannich reaction<br>References Yamaguchi, A., et al.: Chem. Commun. (Cambridge, U. K.), 55, 10567 (2019)<br></p>

<p>Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing.<br>References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)<br></p>

<p>Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.<br>References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)<br></p>

<p>Applications Bromotrimethylsilane is used as a reagent in the synthesis of α-carboxy nucleoside phosphonate analogs as HIV reverse transcriptase-targeting agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keane, S.J., et al.: J. Org. Chem., ahead of print (2014)<br></p>

<p>Stability Hygroscopic<br>Applications Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997); Pfefferkorn, J., et al.: J. Med. Chem., 51, 31 (2008);<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications It is used for synthesis of unsymmetrical biaryls via aromatic C-H borylation-cross-coupling sequence.<br>References Stephens, T. et al.: Org. Lett., 19, 3498 (2017);<br></p>

<p>Applications tert-Butyl-(3-iodo-1,1-dimethyl-propoxy)-dimethyl-silane (cas# 105262-85-9) is used as a reagent in the preparation of Methyl Acetoacetate.<br>References Heslin, J. C., et al.: J. Chem. Soc. [Perkin 1]. 6, 1417 (1988)<br></p>

<p>Stability Moisture Sensitive<br>Applications Chlorotriethylsilane is used in the preparation of potent silylating agent and lewis acid catalyst. Chlorotriethylsilane derivatived ethers have been shown to be more stable towards hydrolysis than are trimethyl ethers.<br> E0<br>References Alvisi, C. et al.: J. Org. Chem., 63, 1330 (1998): Higashiya, S. et al.: J. Org. Chem., 69, 6326 (2004); Hicks, J.D. et al.: Org. Lett., 9, 5621 (2007);<br></p>

<p>Applications Tetramethylammonium Tetrafluoroborate (cas# 661-36-9) is a useful research chemical.<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Neopentyl Glycol Ester is a useful reagent in lapatinib synthesis.<br>References Radl, S., et al.: PCT Int. Appl. (2014), WO 2014059956 A1<br></p>