Outros inibidores
Esta categoria abrange uma ampla variedade de inibidores que não se encaixam nas classificações padrão, mas que ainda são essenciais para várias pesquisas bioquímicas e farmacológicas. Esses inibidores podem direcionar vias, enzimas e interações moleculares únicas ou menos estudadas, fornecendo ferramentas valiosas para áreas de pesquisa especializadas. Na CymitQuimica, oferecemos uma seleção diversificada de inibidores de alta qualidade que abrangem múltiplos alvos biológicos e disciplinas de pesquisa, permitindo que você explore novas vias terapêuticas e aprofunde sua compreensão de processos biológicos complexos.
Foram encontrados 36533 produtos de "Outros inibidores"
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Cremeomycin
CAS:<p>Cremeomycin exhibits activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. It also demonstrates cytotoxic effects in vitro against mouse tumor cell lines P388, L1210, IMC, S180, B16, and SS3.</p>Fórmula:C8H6N2O4Cor e Forma:SolidPeso molecular:194.144Sannamycin F
CAS:Sannamycin F is an aminoglycoside antibiotic that exhibits mild antibacterial activity against both Gram-positive and Gram-negative bacteria.Fórmula:C18H35N5O6Cor e Forma:SolidPeso molecular:417.5STAT3-IN-7
CAS:STAT3-IN-7, an orally active aryl sulfonamido azetidine compound, serves as a STAT3 inhibitor with anticancer activities.Fórmula:C30H26F5N5O4SCor e Forma:SolidPeso molecular:647.62Salfredin C1
CAS:<p>Salfredin C1 is an inhibitor of aldose reductase.</p>Fórmula:C13H11NO6Cor e Forma:SolidPeso molecular:277.229Crotocin
CAS:<p>Crotocin exhibits bactericidal activity against Cryptococcus neoformans, Candida albicans, and Saccharomyces cerevisiae (brewer’s yeast), but it can be inactivated by blood.</p>Fórmula:C19H24O5Cor e Forma:SolidPeso molecular:332.391Kurasoin A
CAS:<p>Kurasoin A is an inhibitor of the enzyme farnesyltransferase.</p>Fórmula:C16H16O3Cor e Forma:SolidPeso molecular:256.296MB725
CAS:MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.Fórmula:C18H21IN4O2SCor e Forma:SolidPeso molecular:484.35Piloquinone
CAS:<p>Piloquinone is a type of phenanthrene compound that exhibits mild inhibitory effects on mycobacteria and protozoa.</p>Fórmula:C21H20O5Cor e Forma:SolidPeso molecular:352.38PF-06815345 hydrochloride
CAS:PF-06815345 HCl is an oral, potent PCSK9 inhibitor, IC50 13.4 μM, lowers PCSK9 in mice.Fórmula:C27H30Cl2FN9O4Cor e Forma:SolidPeso molecular:634.49PLP_Snyder530
PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.Fórmula:C24H24N2O2Cor e Forma:SolidPeso molecular:372.46Ericamycin
CAS:<p>Ericamycin is an antibiotic with antibacterial activity against Gram-positive bacteria. It effectively inhibits Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 0.004 to 0.016 µg/mL.</p>Fórmula:C28H21NO8Cor e Forma:SolidPeso molecular:499.468ETX0282
CAS:ETX0282, oral class A/C β-lactamase inhibitor, developed by Entasis with cefpodoxime for bacterial infections.Fórmula:C13H18FN3O5Cor e Forma:SolidPeso molecular:315.30Purine phosphoribosyltransferase-IN-2
Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.Fórmula:C11H15N5Na4O10P2Cor e Forma:SolidPeso molecular:531.17Bacithrocin D
CAS:<p>Bacithrocin D (Thiolstatin D) inhibits various proteases and has the capability to prolong clotting time. It exhibits IC50 values of 124, 9, 0.85, and 0.01 μM against thrombin, factor Xa, trypsin, and papain, respectively.</p>Fórmula:C17H25N5O3Cor e Forma:SolidPeso molecular:347.412Piperazinomycin
CAS:<p>Piperazinomycin is an antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton.</p>Fórmula:C18H20N2O2Cor e Forma:SolidPeso molecular:296.36NPEC-caged-(S)-3,4-DCPG
CAS:mGlu8a agonistFórmula:C19H16N2O10Pureza:98%Cor e Forma:SolidPeso molecular:432.34TCMDC-125431
TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.Fórmula:C25H27N3O2SCor e Forma:SolidPeso molecular:433.57Chrymutasin A
CAS:<p>Chrymutasin A is a glycoside antitumor antibiotic, known for its cytotoxic properties.</p>Fórmula:C33H33NO13Cor e Forma:SolidPeso molecular:651.614CB-7646
CAS:CB-7646 is a stable trimelamol (TM) analogue, which is an antitumor agent.Fórmula:C8H16N6O2Cor e Forma:SolidPeso molecular:228.25Citreamicin ξ
CAS:<p>Citreamicin ξ exhibits activity against both Gram-positive aerobic and anaerobic bacteria.</p>Fórmula:C30H25NO11Cor e Forma:SolidPeso molecular:575.52Cytochalasin F
CAS:<p>Cytochalasin F reversibly inhibits cytokinesis and possesses various biological activities including the inhibition of macrophage endocytosis and exocytosis.</p>Fórmula:C29H37NO5Cor e Forma:SolidPeso molecular:479.608DI-404
CAS:DI-404: Potent DCN1-UBC12 inhibitor, selectivity blocks cullin 3 neddylation, Kd=6.9 nM.Fórmula:C35H45ClN6O6SPureza:98%Cor e Forma:SolidPeso molecular:713.29MurB-IN-1
MurB-IN-1 (compound 44) inhibits key bacterial enzyme MurB with 3.57 μM affinity, offering treatment potential against P. aeruginosa.Fórmula:C12H7Cl2F3N2O2Cor e Forma:SolidPeso molecular:339.1Hsp90-IN-16
<p>Hsp90-IN-16, a selective HSP90 inhibitor, targets HER2+ cancers with 6 μM IC50 in HCC1954 cells, blocking client proteins and inducing apoptosis.</p>Fórmula:C30H26FN3O6Cor e Forma:SolidPeso molecular:543.54Neoenactin A
CAS:Neoenactin A exhibits potent activity against yeasts and filamentous fungi.Fórmula:C19H36N2O5Cor e Forma:SolidPeso molecular:372.5Polyoxin A
CAS:<p>Polyoxin A is a nucleoside-based antifungal antibiotic.</p>Fórmula:C23H32N6O14Cor e Forma:SolidPeso molecular:616.532Mutalomycin
CAS:Mutalomycin is a polyether antibiotic with activity against Gram-positive bacteria, mycoplasma, and coccidia.Fórmula:C41H70O12Cor e Forma:SolidPeso molecular:754.987Medermycin
CAS:<p>Lactoquinomycin A is a quinone antibiotic displaying activity against Gram-positive bacteria and some Gram-negative bacteria, though its efficacy is weaker against the latter and it is ineffective against fungi. It inhibits various cell lines, including lymphoma L5178Y progenitor cells, doxorubicin-resistant cells, bleomycin-resistant cells, human leukemia K562 cells, murine leukemia L-1210 cells, and murine leukemia P388 cells, with ID50 values (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013, and 0.03, respectively.</p>Fórmula:C24H27NO8Cor e Forma:SolidPeso molecular:457.473Epoxyquinomicin A
CAS:Epoxyquinomicin A is an antibiotic isolated from Amycolatopsissp. It exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus with MIC values of 3-12.5 µg/mL. Additionally, it shows cytotoxicity in cancer cells L1210, B16, and S180, with an IC50 of 2-8 µg/mL. Furthermore, Epoxyquinomicin A demonstrates anti-inflammatory effects in collagen-induced arthritis.Fórmula:C14H10ClNO6Cor e Forma:SolidPeso molecular:323.6855α-reductase-IN-1
CAS:5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.Fórmula:C31H37NO5Pureza:98%Cor e Forma:SolidPeso molecular:503.63Fortimicin B
CAS:Fortimicin B exhibits weak antibacterial activity.Fórmula:C15H32N4O5Cor e Forma:SolidPeso molecular:348.438Glidobactin B
CAS:Glidobactin B is an antitumor antibiotic. It is active against pathogenic fungi and yeasts and can prolong the survival time of mice inoculated with leukemia P388 cells.Fórmula:C29H46N4O6Cor e Forma:SolidPeso molecular:546.699Echinocandin B nucleus
CAS:Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B decarboxylase. It serves as an intermediate in the semisynthetic production of antifungal agents.Fórmula:C34H51N7O15Cor e Forma:SolidPeso molecular:797.807Pluracidomycin C1
CAS:Pluracidomycin C1 is a carbapenem antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria and also possesses β-lactamase inhibitory properties.Fórmula:C10H13NO10S2Cor e Forma:SolidPeso molecular:371.341Citrinin hydrate
CAS:Citrinin hydrate is an inhibitor of human rhinovirus (HRV) 3C protease, with an IC50 of 1.0 mM.Fórmula:C13H16O6Cor e Forma:SolidPeso molecular:268.263Enpp-1-IN-12
<p>ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.</p>Fórmula:C17H19N5O3SCor e Forma:SolidPeso molecular:373.43Cedarmycin B
CAS:Cedarmycin B exhibits activity against Candida, Cryptococcus neoformans, and Aspergillus fumigatus, with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL.Fórmula:C12H18O4Cor e Forma:SolidPeso molecular:226.269PDE4B-IN-3
PDE4B-IN-3 is a potent inhibitor of PDE4B (IC50: 0.94 μM) and exhibits anti-inflammatory effects.Fórmula:C30H35N3O4S2Cor e Forma:SolidPeso molecular:565.75Fonsartan free acid
CAS:Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Fórmula:C26H32N4O5S2Pureza:98%Cor e Forma:SolidPeso molecular:544.69Melithiazole A
CAS:<p>Melithiazol A is an antibiotic and a potent β-methoxyacrylate (MOA) inhibitor with antifungal and cytotoxic properties.</p>Fórmula:C20H26N2O4S2Cor e Forma:SolidPeso molecular:422.561mPGES1-IN-5
CAS:mPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.Fórmula:C27H27N3OCor e Forma:SolidPeso molecular:409.52Leucomycin V
CAS:Leucomycin V is a macrolide antibiotic. Leucomycin A9 exhibits strong activity against Gram-positive bacteria and also affects spirochetes, rickettsiae, and chlamydiae.Fórmula:C35H59NO13Cor e Forma:SolidPeso molecular:701.842AEP-IN-1
<p>APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.</p>Fórmula:C18H27N3O3Cor e Forma:SolidPeso molecular:333.43Exfoliazone
CAS:Exfoliazone is a phenazinic antibiotic with activity against Trichoderma viride, exhibiting an ED50 for inhibiting mycelial growth of 70 μg/mL.Fórmula:C15H12N2O4Cor e Forma:SolidPeso molecular:284.267Neuraminidase-IN-7
Neuraminidase-IN-7, a thiophene, inhibits neuraminidase (IC50 0.03 μM), showing promise for flu research.Fórmula:C21H20N2O6SCor e Forma:SolidPeso molecular:428.46AS-1940477 hydrobromide
CAS:AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.Fórmula:C24H23BrFN5O2Cor e Forma:SolidPeso molecular:512.38Rosiptor acetate
CAS:Rosiptor (AQX-1125) activates SHIP1, inhibits Akt, and reduces inflammation and allergy in rodents.Fórmula:C22H39NO4Pureza:98%Cor e Forma:Solid PowderPeso molecular:381.55AT1R antagonist 2
<p>AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).</p>Fórmula:C29H37N5O4S2Cor e Forma:SolidPeso molecular:583.77Herbimycin B
CAS:Herbimycin B, an ansamycin antibiotic, functions as an inhibitor of Src family kinases. It exhibits herbicidal effects on most monocotyledonous and dicotyledonous plants and can inhibit the activity of tobacco mosaic virus (TMV), HeLa cells, and Ehrlich cells.Fórmula:C29H40N2O7Cor e Forma:SolidPeso molecular:528.637Tabimorelin hemifumarate
CAS:orally active ghrelin receptor (GHS-R1a) agonistFórmula:C32H40N403C4H404Pureza:98%Cor e Forma:SolidPeso molecular:586.72Exophilin A
CAS:<p>Exophilin A is an antibiotic that exhibits activity against Gram-positive bacteria.</p>Fórmula:C30H56O10Cor e Forma:SolidPeso molecular:576.76Treloxinate
CAS:<p>Treloxinate is an effective lipid-lowering agent. It specifically influences the triglyceride levels in Sprague-Dawley rats, while impacting both triglyceride and cholesterol levels in Wistar rats.</p>Fórmula:C16H12Cl2O4Cor e Forma:SolidPeso molecular:339.17Curvularol
CAS:<p>Curvularol exhibits mild antifungal activity but lacks antibacterial effects. At a concentration of 150 ng/mL, it can inhibit the cell cycle progression of normal rat renal cells (G1 phase NRK). Additionally, 100 ng/mL of Curvularol can restore the morphology of deformed NRK cells induced by SRCTS. Curvularol also inhibits protein synthesis.</p>Fórmula:C15H22O4Cor e Forma:SolidPeso molecular:266.333CI 992
CAS:<p>CI 992 is a novel potent inhibitor of primate renin.</p>Fórmula:C33H52N6O7S2Cor e Forma:SolidPeso molecular:708.93Glucosylceramide synthase-IN-3
Glucosylceramide synthase-IN-3 (BZ1) is a potent, brain-accessible, oral GCS inhibitor with a 16 nM IC50, relevant for Gaucher's disease study.Fórmula:C21H20FN3O3Cor e Forma:SolidPeso molecular:381.4Dykellic acid
CAS:<p>Dykellic acid is a RhoA inhibitor. It can suppress the migration and motility of B16 cells and inhibit the tubular formation of HUVECs. Dykellic acid shows potential for use in cancer research.</p>Fórmula:C14H16O4Cor e Forma:SolidPeso molecular:248.2743-O-Demethylmonensin A
CAS:3-O-Demethylmonensin A is a polyether antibiotic produced by Streptomyces cinnamonensis (strain LO-63).Fórmula:C35H60O11Cor e Forma:SolidPeso molecular:656.84Pradimicin B
CAS:Pradimicin B is an antibiotic with potent antifungal and anti-yeast activities.Fórmula:C35H36N2O14Cor e Forma:SolidPeso molecular:708.665IDX-320
CAS:IDX-320 is an HCV protease inhibitor.Fórmula:C37H43F3N6O7S2Cor e Forma:SolidPeso molecular:804.920-Deoxysalinomycin
CAS:<p>20-Deoxysalinomycin primarily targets Gram-positive bacteria, with a particular effectiveness against poultry coccidia.</p>Fórmula:C42H70O10Cor e Forma:SolidPeso molecular:735.00Megovalicin A
CAS:<p>Megovalicin A is effective against Bacillus subtilis and Escherichia coli.</p>Fórmula:C35H63NO8Cor e Forma:SolidPeso molecular:625.88SX 3202
CAS:<p>SX 3202 is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.</p>Fórmula:C17H11BrFN3O4Cor e Forma:SolidPeso molecular:420.19Peptaibolin
CAS:<p>Peptaibolin exhibits activity against Gram-positive bacteria and yeast. The minimum inhibitory concentration (MIC) for its effect on Bacillus subtilis [ATCC 6633] and Candida albicans is 100 μg/mL.</p>Fórmula:C31H51N5O6Cor e Forma:SolidPeso molecular:589.77Fluoropolyoxin L
CAS:Fluoropolyoxin L exhibits inhibitory activity against Escherichia coli and Enterococcus faecalis.Fórmula:C16H22FN5O12Cor e Forma:SolidPeso molecular:495.371Miyakamide A2
CAS:<p>Miyakamide A2 is an antibiotic with insecticidal properties. It inhibits the growth of brine shrimp and exhibits weak activity against Xanthomonas species. The IC50 for inhibiting P388 cells is 12.2 μg/mL.</p>Fórmula:C31H32N4O3Cor e Forma:SolidPeso molecular:508.611Monamycin H1
CAS:Monamycin H1 is an ester peptide antibiotic that exhibits activity against Gram-positive bacteria.Fórmula:C34H56ClN7O8Cor e Forma:SolidPeso molecular:726.30(rel)-Myrislignan
CAS:(rel)-Myrislignan, a lignan compound with a relative configuration, has been isolated from Myristica fragrans Houtt.Fórmula:C21H26O6Pureza:98%Cor e Forma:SolidPeso molecular:374.43Malioxamycin
CAS:<p>Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by suppressing peptidoglycan synthesis in the bacterial cell wall and promoting the formation of protoplasts.</p>Fórmula:C9H16N2O6Cor e Forma:SolidPeso molecular:248.233Kahweol linoleate
CAS:Kahweol linoleate, a semi-synthetic from coffee, blocks osteoclast creation, fights cancerous cells, prevents DNA damage, and reduces oxidative stress.Fórmula:C38H56O4Cor e Forma:SolidPeso molecular:576.85Bacithrocin B
CAS:<p>Bacithrocin B is a thrombin inhibitor that suppresses the activity of thrombin, Factor Xa, trypsin, and papain, with IC50 values of 84 μM, 17 μM, 1.7 μM, and 0.02 μM, respectively.</p>Fórmula:C19H29N5O3Cor e Forma:SolidPeso molecular:375.465Chlorflavonin
CAS:<p>Chlorflavonin exhibits antifungal activity against several fungi, including Aspergillus, yeast, and Botrytis cinerea, with exceptionally strong activity against Aspergillus nidulans, where the minimum inhibitory concentration is as low as 0.08 μg/mL.</p>Fórmula:C18H15ClO7Cor e Forma:SolidPeso molecular:378.76120-Deoxynarasin
CAS:20-Deoxynarasin exhibits activity against Gram-positive bacteria, mycoplasma, coccidia, and viruses, and it also promotes growth.Fórmula:C43H72O10Cor e Forma:SolidPeso molecular:749.03Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.Fórmula:C21H24ClN7Cor e Forma:SolidPeso molecular:409.9223-De(mycinosyloxy)tylosin
CAS:<p>23-De(mycinosyloxy)tylosin is a macrolide antibiotic exhibiting activity against Gram-positive bacteria, with limited efficacy against Gram-negative bacteria and mycoplasma.</p>Fórmula:C38H63NO12Cor e Forma:SolidPeso molecular:725.91Methylenomycin A
CAS:<p>Methylenomycin A is a cyclopentanone-derived antibiotic effective against both Gram-negative and Gram-positive bacteria.</p>Fórmula:C9H10O4Cor e Forma:SolidPeso molecular:182.173Chloroquinocin
CAS:<p>Chloroquinocin exhibits moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).</p>Fórmula:C17H15ClO5Cor e Forma:SolidPeso molecular:334.751PDE4-IN-5
PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.Fórmula:C21H28N2O3Cor e Forma:SolidPeso molecular:356.46Inactone
CAS:<p>Inactone is a biologically active molecule with a 3-pentanoylimino group that inhibits the large ribosomal subunit.</p>Fórmula:C15H21NO4Cor e Forma:SolidPeso molecular:279.332DDCPPB-Glu
CAS:DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.Fórmula:C22H27N5O5Pureza:98%Cor e Forma:SolidPeso molecular:441.48SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Fórmula:C36H38N2O2Cor e Forma:SolidPeso molecular:530.710-Hydroxyundeca-2,4,6,8-tetraynamide
CAS:<p>10-Hydroxyundeca-2,4,6,8-tetraynamide is a polyacetylene antibiotic exhibiting activity against Gram-positive and Gram-negative bacteria, yeasts, fungi, as well as cytotoxic properties.</p>Fórmula:C11H7NO2Cor e Forma:SolidPeso molecular:185.179Ceclazepide
CAS:Ceclazepide is an antagonist of cholecystokinin receptor.Fórmula:C30H32N6O5Pureza:98%Cor e Forma:SolidPeso molecular:556.6111-Deacetoxywortmannin
CAS:11-Deacetoxywortmannin is an antibiotic with potent antibacterial and anti-inflammatory properties, and it also exhibits anti-edema effects.Fórmula:C21H22O6Cor e Forma:SolidPeso molecular:370.3964-Diazo-3-methoxy-2,5-cyclohexadien-1-one
CAS:<p>4-Diazo-3-methoxy-2,5-cyclohexadien-1-one demonstrates notable activity against anaerobic bacteria. Minimum inhibitory concentrations (MIC) are 0.4 μg/mL for Clostridium and Bacteroidetes, and 0.2 μg/mL for Haemophilus.</p>Fórmula:C7H6N2O2Cor e Forma:SolidPeso molecular:150.14AZD2353
CAS:<p>AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).</p>Fórmula:C22H19ClFN3O3Cor e Forma:SolidPeso molecular:427.86Chitinovorin A
CAS:<p>Chitinovorin A is a β-lactam antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.</p>Fórmula:C26H41N9O11SCor e Forma:SolidPeso molecular:687.722Danavorexton
CAS:Danavorexton is an orexin receptor agonist.Fórmula:C21H32N2O5SCor e Forma:SolidPeso molecular:424.55Protectin D1
CAS:<p>Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by nerve cells and is a potential cardioprotective agent.</p>Fórmula:C22H32O4Pureza:99.72% - 99.79%Cor e Forma:SolidPeso molecular:360.49MDL-27788
CAS:<p>MDL-27788 is a tricyclic inhibitor.</p>Fórmula:C24H26N2O5SCor e Forma:SolidPeso molecular:454.54Amidomycin
CAS:<p>Amidomycin is an antibiotic that primarily targets yeast.</p>Fórmula:C40H68N4O12Cor e Forma:SolidPeso molecular:796.99PD-149163
CAS:<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Fórmula:C42H71N9O6Cor e Forma:SolidPeso molecular:798.07Aristoforin
CAS:<p>Aristoforin is a SIRT1 and SIRT2 inhibitor that induces cell cycle arrest, shows potent antitumor effects, and inhibits lymphangiogenesis in vivo.</p>Fórmula:C37H54O6Cor e Forma:SolidPeso molecular:594.82Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.77DMP 728
CAS:<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Fórmula:C26H40N8O10SPureza:98%Cor e Forma:SolidPeso molecular:656.71Cyclacidin
CAS:<p>Cyclacidin exhibits activity against Gram-positive bacteria, such as Bacillus subtilis and Gambosia occidentalis, and demonstrates inhibitory effects on Sarcoma 180, among others.</p>Fórmula:C22H16O7Cor e Forma:SolidPeso molecular:392.358Dioxamycin
CAS:<p>Dioxamycin exhibits activity against Gram-positive bacteria and inhibits Staphylococcus aureus 209P with a minimum inhibitory concentration (MIC) of 3.12 μg/mL. It also suppresses the proliferation of L1210, P388, IMC, LX-1, and SC-6 cells with IC50 values (μg/mL) of 2.7, 1.4, 6.0, 2.0, and 2.5, respectively.</p>Fórmula:C38H40O15Cor e Forma:SolidPeso molecular:736.715Heme Oxygenase-2-IN-1
Heme Oxygenase-2-IN-1 is a selective HO-2 inhibitor with IC50s: 14.9 μM (HO-1), 0.9 μM (HO-2).Fórmula:C19H17N3O2Cor e Forma:SolidPeso molecular:319.368(S),15(S)-DiHETE
CAS:<p>8(S),15(S)-DiHETE, from 15(S)-HETE's oxidation by 15-LO, triggers eosinophil movement at 1.5 μM; it counteracts pain and LTB4 effects.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47Oudenone
CAS:<p>Oudenone is an oxygen-containing heterocyclic antibiotic with mild antibacterial and antifungal properties. It also exhibits antihypertensive effects in rats with spontaneous hypertension.</p>Fórmula:C12H16O3Cor e Forma:SolidPeso molecular:208.254SHR0687
CAS:<p>SHR0687: potent KOR agonist, selective, favorable PK, effective in rat pain model, minimal BBB penetration, less CNS side effects.</p>Fórmula:C39H60N8O5Cor e Forma:SolidPeso molecular:720.94IT-066 HCl
CAS:<p>IT-066 HCl is a histamine H2 receptor antagonist.</p>Fórmula:C19H25ClN4O3Cor e Forma:SolidPeso molecular:392.88P2X7 receptor antagonist-1
P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.Fórmula:C22H20F4N2O3Cor e Forma:SolidPeso molecular:436.4Cephamycin A
CAS:<p>Cephamycin A exhibits weak activity against both Gram-positive and Gram-negative bacteria.</p>Fórmula:C25H29N3O14S2Cor e Forma:SolidPeso molecular:659.6393-IN-PP1
CAS:<p>3-IN-PP1: PKD inhibitor (IC50: 94-108 nM for PKD1/2/3), broad anticancer agent for research.</p>Fórmula:C17H18N6Cor e Forma:SolidPeso molecular:306.36MF-592
CAS:<p>MF-592: EP4 receptor antagonist, hEP4 IC50 3 nM, hWB IC50 78 nM, great oral PK, rat arthritis ED50 0.1 mg/kg/day, promising for development.</p>Fórmula:C34H33Cl2N3O6SCor e Forma:SolidPeso molecular:682.61MSX-3 free acid
CAS:MSX-3 free acid is an A2A adenosine receptor antagonist and a prodrug of MSX-2.Fórmula:C21H23N4O7PCor e Forma:SolidPeso molecular:474.40β-Carotene-15,15'-epoxide
CAS:β-Carotene-15,15ʹ-epoxide acts as an XIAP antagonist with pro-apoptotic (Apoptosis) and anti-tumor properties, found in the leaves of Spondias mombin. In rat models of DMBA-induced breast cancer, it induces tumor cell apoptosis by binding to the BIR3 domain of the XIAP protein, thereby inhibiting its interaction with caspase-9. Additionally, β-carotene-15,15ʹ-epoxide significantly reduces BCL-2, COX-2, and TNF-α expression in tumor tissue, decreases MDA levels, enhances catalase activity, and modulates biochemical markers in serum such as LDH, ALP, and ALT, indicating its antioxidant, anti-inflammatory, and metabolic protective effects. This compound is useful for researching inflammation-related diseases and tumors such as breast cancer.Fórmula:C40H56OCor e Forma:SolidPeso molecular:552.872MEN-10354
CAS:<p>MEN-10354 is a less potent and less selective NK-2 tachykinin receptor antagonist compared to the linear analog, R 396.</p>Fórmula:C37H46N8O9Cor e Forma:SolidPeso molecular:746.81Darlucin B
CAS:<p>Darlucin B exhibits both antibacterial and antifungal properties, and it possesses mild cytotoxicity.</p>Fórmula:C19H20N2O3Cor e Forma:SolidPeso molecular:324.374Fistupyrone
CAS:<p>Fistupyrone, an antibiotic, is a microbial metabolite found in Streptomyces (TP-A0569). It has the ability to inhibit infections caused by Alternaria brassicicola in Chinese cabbage.</p>Fórmula:C10H14O3Cor e Forma:SolidPeso molecular:182.216MK-8318
CAS:MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Fórmula:C27H26F4N2O5Pureza:98%Cor e Forma:SolidPeso molecular:534.5TP-6076
CAS:TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A.Fórmula:C28H32F3N3O7Cor e Forma:SolidPeso molecular:579.568-iso Prostaglandin F3α
CAS:8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.475-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione
CAS:5-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione is an inhibitor of xanthine oxidase (XO) found in the fungus Peniophora sanguinea.Fórmula:C26H16O4Cor e Forma:SolidPeso molecular:392.402-Hydroxygentamicin B
CAS:<p>2-Hydroxygentamicin B is an aminoglycoside antibiotic with activity against both Gram-positive and Gram-negative bacteria.</p>Fórmula:C19H38N4O11Cor e Forma:SolidPeso molecular:498.525Topoisomerase II inhibitor 6
Topoisomerase II inhibitor 6, a potent tryptanthrin derivative, blocks G2 phase in CCRF-CEM cells, induces DNA breaks, and may be used for cancer research.Fórmula:C19H18N4O2Cor e Forma:SolidPeso molecular:334.37Epiderstatin
CAS:<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Fórmula:C15H20N2O4Cor e Forma:SolidPeso molecular:292.33Lp-PLA2-IN-5
CAS:<p>Lp-PLA2-IN-5 inhibits Lp-PLA2 and PAF-AH, potentially useful in Alzheimer's and atherosclerosis studies.</p>Fórmula:C23H18F5N3O4Cor e Forma:SolidPeso molecular:495.4RORγt modulator 5
CAS:<p>RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.</p>Fórmula:C27H22F5N3O6SCor e Forma:SolidPeso molecular:611.54BI-207524
CAS:BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.Fórmula:C35H36ClN5O5Cor e Forma:SolidPeso molecular:642.14PI3K-IN-23
PI3K-IN-23 is a (E)-9-oxooctadec-10-en-12-ynoic acid analogue that promotes glucose uptake (EC50: 7.00 μM).Fórmula:C24H33NO4SCor e Forma:SolidPeso molecular:431.59Glidobactin G
CAS:<p>Glidobactin G is an antitumor antibiotic with activity against pathogenic fungi and yeasts. Additionally, Glidobactin G prolongs the survival time of mice inoculated with leukemia P388 cells.</p>Fórmula:C27H44N4O7Cor e Forma:SolidPeso molecular:536.661Leucomycin A9
CAS:<p>Leucomycin A9 is a macrolide antibiotic known for its potent activity against Gram-positive bacteria. It is also effective against spirochetes, rickettsiae, and chlamydiae.</p>Fórmula:C37H61NO14Cor e Forma:SolidPeso molecular:743.878Emerin
CAS:<p>Emerin is an antibiotic found in the Aspergillus nidulans strain.</p>Fórmula:C20H16N2O2Cor e Forma:SolidPeso molecular:316.353UNC7467
CAS:UNC7467, potent IP6K2/1/6 inhibitor (4.9/8.9/1320 nM); lowers inositol pyrophosphates, minimal impact on other inositol phosphates; for obesity research.Fórmula:C20H13NO3Pureza:98.28% - 98.64%Cor e Forma:SoildPeso molecular:315.3218-Deoxyherboxidiene
CAS:<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Fórmula:C25H42O5Cor e Forma:SolidPeso molecular:422.69-cis-13,14-Dihydroretinoic acid
CAS:<p>9-cis-13,14-Dihydroretinoic acid (9CDHRA) is a selective retinoid X receptor (RXR) agonist with a Kd of 90 nM. It can ameliorate memory deficits caused by impaired RXR signaling in vivo. This compound shows potential for research in the fields of neuroscience and metabolic diseases.</p>Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.451Naphthablin
CAS:<p>Naphthablin is a naphthoquinone compound that inhibits the function of the Abl oncogene. It prevents the morphological transformation of v-ablts-NIH3T3 cells induced by Abl and also suppresses RNA synthesis.</p>Fórmula:C29H36O8Cor e Forma:SolidPeso molecular:512.591Vicanicin
CAS:Vicanicin is an aryl phenol ether compound found in lichens. It inhibits the expression of Hsp70, modulates intracellular redox-sensitive mechanisms, increases reactive oxygen species (ROS) in cancer cells, alters the Bax/Bcl-2 ratio, activates caspase-3, and induces apoptosis. Vicanicin suppresses cell growth and promotes apoptosis in androgen-sensitive (LNCaP) and androgen-insensitive (DU-145) human prostate cancer cells. It holds potential for prostate cancer research.Fórmula:C18H16Cl2O5Cor e Forma:SolidPeso molecular:383.223Nepaprazole sodium
CAS:Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.Fórmula:C18H18N3NaO2SCor e Forma:SolidPeso molecular:363.41KHK-IN-6
CAS:KHK-IN-6 (compound 33) acts as a KHK inhibitor with an IC50 of 0.6nM.Fórmula:C23H24F3N5O2SCor e Forma:SolidPeso molecular:491.53ALK5-IN-82
CAS:<p>ALK5-IN-82 is a potent and selective inhibitor of activin receptor-like kinase 5 (ALK5), demonstrating an IC50 value of 9.1 nM. This compound effectively suppresses the expression of α-smooth muscle actin (α-SMA), collagen I, and the proteinases tissue inhibitor of metalloproteinase 1 (TIMP-1) and matrix metalloproteinase 13 (MMP-13) in human umbilical vein endothelial cells induced by transforming growth factor-β. ALK5-IN-82 shows potential for use in research related to cardiac fibrosis.</p>Fórmula:C22H19N7OSCor e Forma:SolidPeso molecular:429.501-Hydroxy-2-nonyn-4-one
CAS:<p>1-Hydroxy-2-nonyn-4-one is an antibiotic with activity against yeasts, filamentous fungi, tumors, and shows weak efficacy against both Gram-positive and Gram-negative bacteria.</p>Fórmula:C9H14O2Cor e Forma:SolidPeso molecular:154.206XN methyl pyrazole
<p>XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].</p>Fórmula:C22H24N2O4Cor e Forma:SolidPeso molecular:380.44Bagremycin B
CAS:<p>Bagremycin B is produced by the bacterium Streptomyces strain Tu 4128. It exhibits weak activity against Gram-positive bacteria, Saccharomyces cerevisiae, and Candida albicans.</p>Fórmula:C17H15NO4Cor e Forma:SolidPeso molecular:297.305Cytosaminomycin A
CAS:<p>Cytosaminomycin A is an antibiotic with anticoccidial and antibacterial properties.</p>Fórmula:C22H34N4O8SCor e Forma:SolidPeso molecular:514.592ABCA1 inducer 1
CAS:<p>ABCA1 inducer 1, a non-lipid inducer of ABCA1, enhances ABCA1 expression in E3/4FAD mice expressing human APOE 3/4, augments the lipidation of apolipoprotein (APOE), and reverses various Alzheimer's disease (AD) phenotypes without increasing triglycerides.</p>Fórmula:C24H24Cl2N2O7S2Cor e Forma:SolidPeso molecular:587.49NSC-217913
CAS:NSC-217913 acts as an inhibitor of WWP1, exhibiting an IC50 value of 158.3 μM.Fórmula:C9H8Cl2N4O2SCor e Forma:SolidPeso molecular:307.16MMP408
CAS:<p>MMP408 acts as an inhibitor of MMP-12.</p>Fórmula:C19H20N2O7SCor e Forma:SolidPeso molecular:420.44Kri 1314
CAS:Kri 1314 is a cyclohexyl-norstatine-containing dipeptide renin inhibitor which has potential for the treatment of hypertension.Fórmula:C38H51N5O7Cor e Forma:SolidPeso molecular:689.84mPGES1-IN-4
CAS:<p>mPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.</p>Fórmula:C27H25F2N3OCor e Forma:SolidPeso molecular:445.5015(R)-Lipoxin A4
CAS:<p>Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.47RIPK1-IN-24
CAS:<p>RIPK1-IN-24 is an inhibitor of receptor-interacting protein kinase 1 (RIPK1) with an IC50 of 1.3 μM. It is utilized in research on inflammatory diseases.</p>Fórmula:C26H21FN6O2Cor e Forma:SolidPeso molecular:468.48RIPK1-IN-26
CAS:<p>RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.</p>Fórmula:C15H20FNO2Cor e Forma:SolidPeso molecular:265.32Vitamin A Propionate
CAS:<p>Vitamin A Propionate, an ester derivative of vitamin A, exhibits varying effects on growth, serum biochemistry, and hematological indices in foal nutrition studies depending on the dosage administered. Both excessively high and low doses lead to adverse impacts. These effects are correlated with the concentrations of vitamin A in the plasma, liver, and kidneys.</p>Fórmula:C23H34O2Cor e Forma:SolidPeso molecular:342.51Tembotrione
CAS:<p>Tembotrione is a chemical compound that may reduce the productivity of carrots. It possesses activity that degrades the quality of carrot stems. Additionally, Tembotrione can be used in studies focusing on the overall productivity of carrot cultivation.</p>Fórmula:C17H16ClF3O6SCor e Forma:SolidPeso molecular:440.82Napsagatran hydrate
CAS:Napsagatran hydrate is a novel and specific inhibitor of thrombin.Fórmula:C26H36N6O7SPureza:98%Cor e Forma:SolidPeso molecular:576.66KCL-440
CAS:RS 57639 is a bioactive chemical.Fórmula:C18H18N2O2Cor e Forma:SolidPeso molecular:294.35Curvulic acid
CAS:<p>Curvulic acid exhibits relatively weak activity against both Gram-positive and Gram-negative bacteria.</p>Fórmula:C11H12O6Cor e Forma:SolidPeso molecular:240.209Carzinophillin A
CAS:<p>Carzinophillin A exhibits inhibitory effects on both ascites carcinoma and Yoshida sarcoma.</p>Fórmula:C31H33N3O11Cor e Forma:SolidPeso molecular:623.607CJ-887
CAS:<p>CJ-887 is a STAT3 inhibitor.</p>Fórmula:C34H45N6O10PCor e Forma:SolidPeso molecular:728.73Carpetimycin D
CAS:<p>Carpetimycin D exhibits potent activity against both Gram-positive and Gram-negative bacteria, including those that produce β-lactamase. Additionally, Carpetimycin D strongly inhibits β-lactamase.</p>Fórmula:C14H20N2O9S2Cor e Forma:SolidPeso molecular:424.447KMN-80
CAS:<p>KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.</p>Fórmula:C21H33NO4Cor e Forma:SolidPeso molecular:363.49Anticancer agent 27
Anticancer agent 27 is a promising candidate for the treatment of cancer and deserves further development.Fórmula:C28H31NO6Cor e Forma:SolidPeso molecular:477.55Darlucin A
CAS:<p>Darlucin A exhibits both antibacterial and antifungal properties, accompanied by mild cytotoxicity.</p>Fórmula:C19H16N2O3Cor e Forma:SolidPeso molecular:320.342HS-731
CAS:HS-731 is a μ-Opioid Receptor Agonist.Fórmula:C20H26N2O5Cor e Forma:SolidPeso molecular:374.43PD 113271
CAS:PD 113,271 is an analog of the fermentation products fostriecin with antitumor activity in vitro and in vivo.Fórmula:C19H27O10PPureza:98%Cor e Forma:SolidPeso molecular:446.39Oximidine Ⅲ
CAS:<p>Oximidine III is an antitumor antibiotic that selectively inhibits the growth of rat fibroblast 3Y1 cells and induces mutations in various tumor genes. The inhibitory effects of Oximidine III on vH-ras-3Y1, v-src-3Y1 cells, and normal 3Y1 cells have IC50 values of 14 nM, 4.5 nM, and 140 nM, respectively. Additionally, Oximidine III arrests cells with RAS or SRC mutations in the G1 phase of the cell cycle and increases the expression of p21WAF1.</p>Fórmula:C23H24N2O6Cor e Forma:SolidPeso molecular:424.45Basroparib
CAS:Basroparib is an inhibitor of ribose polymerase (PARP) and has shown antitumour effects.Fórmula:C18H21F2N7O3Cor e Forma:SolidPeso molecular:421.4Adecypenol
CAS:Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.Fórmula:C12H16N4O4Pureza:98%Cor e Forma:SolidPeso molecular:280.28BM635 hydrochloride (1493762-74-5 free base)
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Fórmula:C25H30ClFN2OPureza:98%Cor e Forma:SolidPeso molecular:428.97P2X receptor-1
P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.Fórmula:C14H14ClN3O3S2Cor e Forma:SolidPeso molecular:371.86Chuangxinmycin
CAS:<p>Chuangxinmycin is an antibiotic that can be isolated from Actinoplanes tsinanensis CPCC 200056. It exhibits antibacterial activity both in vitro and in vivo, making it useful for research related to infections.</p>Fórmula:C12H11NO2SCor e Forma:SolidPeso molecular:233.286Nanaomycin D
CAS:<p>Nanaomycin D is an antibiotic with antibacterial properties.</p>Fórmula:C16H12O6Cor e Forma:SolidPeso molecular:300.263Mepixetil
Mepixetil is a potent angiotensin II receptor antagonist[1].Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28Gypsetin
CAS:<p>Gypsetin inhibits the activity of acyl-CoA:cholesterol acyltransferase (ACAT), showing inhibitory effects on rat liver microsomal ACAT with an IC50 of 18 μM, and competes with oleoyl-CoA substrate, possessing a Ki value of 5.5 μM. Additionally, Gypsetin prevents the formation of cholesterol esters from oleic acid with an IC50 of 0.65 μM.</p>Fórmula:C32H36N4O4Cor e Forma:SolidPeso molecular:540.653DSP-6952
CAS:DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.Fórmula:C21H32BrClN4O5Cor e Forma:SolidPeso molecular:535.86CGS 22652
CAS:<p>CGS 22652 has thromboxane receptor antagonism combined with thromboxane synthase inhibition.</p>Fórmula:C22H29ClN2O4SCor e Forma:SolidPeso molecular:452.99BM635 mesylate (1493762-74-5 free base)
BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Fórmula:C26H33FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:488.61Cycloleucomelone
CAS:<p>Cycloleucomelone is a secondary metabolite and a fungal pigment.</p>Fórmula:C18H10O7Cor e Forma:SolidPeso molecular:338.268Dihydrokainic acid
CAS:EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptakeFórmula:C10H17NO4Pureza:98%Cor e Forma:SolidPeso molecular:215.25Pefcalcitol
CAS:Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.Fórmula:C26H34F5NO4Cor e Forma:SolidPeso molecular:519.54AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Fórmula:C24H23N3O4S3Cor e Forma:SolidPeso molecular:513.65MPro N3
CAS:Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.Fórmula:C35H48N6O8Cor e Forma:SolidPeso molecular:680.79Depsidomycin
CAS:<p>Depsidomycin is an immunomodulatory antibiotic isolated from the culture broth of Streptomyces lavendofoliae MI951-62F2, exhibiting immunosuppressive properties. It primarily shows antibacterial activity against Gram-positive bacteria.</p>Fórmula:C38H65N9O9Cor e Forma:SolidPeso molecular:791.978MU1656
CAS:<p>MU1656 is a selective inhibitor of histone methyltransferase DOT1L, which significantly inhibits cancer cell proliferation in hematological malignancies.</p>Fórmula:C32H45N7O2Pureza:96.92%Cor e Forma:SolidPeso molecular:559.75Anticancer agent 62
CAS:Anticancer agent 62 inhibits HepG2, Bel-7402, MCF-7 growth with IC50: 0.019, 0.060, 0.016 μM respectively, and halts tumors.Fórmula:C20H19ClN3Na2O8PSCor e Forma:SolidPeso molecular:573.85GNE-616
CAS:<p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>Fórmula:C24H23F4N5O3SPureza:98%Cor e Forma:SolidPeso molecular:537.53Pim-1 kinase inhibitor 3
CAS:<p>Pim-1 kinase inhibitor 3 (Compound H5) is a potent inhibitor of Pim-1 kinase, demonstrating an inhibitory concentration (IC50) of 35.13 nM [1].</p>Fórmula:C20H25N3O2Cor e Forma:SolidPeso molecular:339.43Diarylalkane derivative 1
CAS:Diarylalkane derivative 1 is used for the research of pancreatitis.Fórmula:C34H51NO4Pureza:98%Cor e Forma:SolidPeso molecular:537.77Tyk2-IN-10
CAS:<p>Tyk2-IN-10 acts as an inhibitor of the Tyrosine Kinase 2 (Tyk2)-mediated signaling pathway, which plays a role in inflammation regulation.</p>Fórmula:C25H27N5O3Cor e Forma:SolidPeso molecular:445.51BRD4-IN-9
CAS:<p>BRD4-IN-9, an orally active BRD4 inhibitor, demonstrates a potent IC50 of 9.4 nM. In a murine melanoma xenograft model, it effectively inhibits tumor growth.</p>Fórmula:C24H23N3O3Cor e Forma:SolidPeso molecular:401.46JBJ-08-178-01
CAS:JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.Fórmula:C31H30N8O3Cor e Forma:SolidPeso molecular:562.62HMGB1-IN-3
CAS:<p>HMGB1-IN-3 (compound E), a derivative of glycyrrhizic acid, exhibits potent inhibitory effects on HMGB1 (high mobility group protein 1). It is utilized in research related to intracerebral hemorrhage.</p>Fórmula:C31H46O4Cor e Forma:SolidPeso molecular:482.69Curromycin B
CAS:Curromycin B exhibits antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. It also inhibits the replication of human immunodeficiency virus (HIV) and suppresses the proliferation of mouse melanoma B16 and leukemia P388 cells.Fórmula:C37H53N3O9Cor e Forma:SolidPeso molecular:683.831MDK-3298
CAS:MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).Fórmula:C35H32BN3O7Pureza:98%Cor e Forma:SolidPeso molecular:617.46PPO-IN-15
CAS:PPO-IN-15 (compound (R)-I-5) serves as an inhibitor of protoporphyrinogen IX oxidase (PPO), offering efficacy against resistant weeds while maintaining safety for wheat and rice.Fórmula:C17H18ClFN4O5SCor e Forma:SolidPeso molecular:444.87(S)-Dexfadrostat
CAS:(S)-Dexfadrostat ((S)-Fadrozole), an aromatase inhibitor, exhibits an IC 50 of 4.6 nM in in vitro assays using human placental microsomes. It is applicable for research on estrogen-dependent breast cancer, gynecomastia, and systemic lupus erythematosus.Fórmula:C14H13N3Cor e Forma:SolidPeso molecular:223.27Fluopsin F
CAS:<p>Fibrostatin F is a metal-containing iron antibiotic with potent activity against Gram-positive and Gram-negative bacteria, as well as antitumor properties.</p>Fórmula:C6H12FeN3O3S3Cor e Forma:SolidPeso molecular:326.2182-PPA
CAS:2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.Fórmula:C11H10N2Cor e Forma:SolidPeso molecular:170.219(R)-HETE
CAS:<p>9(R)-HETE, 50% of racemic mix, activates RXRγ 1.5x at 300 nM; identified by HPLC comparison.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47Urease-IN-16
CAS:<p>Urease-IN-16, with an IC50 of 132 µmol/L, is a urease inhibitor that coordinates with nickel atoms through the oxygen atoms of either carbonyl or boronic acid groups. This compound holds significant potential as an additive in the development of efficient fertilizers and medical applications.</p>Fórmula:C14H17BN2O4SCor e Forma:SolidPeso molecular:320.17Exfoliamycin
CAS:<p>Exfoliamycin is a naphthoquinone antibiotic found in the Streptomyces strain Exfoliamycin Tu 1424, and it exhibits activity against Gram-positive bacteria.</p>Fórmula:C22H26O9Cor e Forma:SolidPeso molecular:434.436DD04107
CAS:<p>DD04107 inhibits α-CGRP release, targets Synaptotagmin 1 in sensory neurons.</p>Fórmula:C48H88N14O12SCor e Forma:SolidPeso molecular:1085.36Detajmium
CAS:Detajmium is an anti-arrhythmia compound. It is an Na(+)-channel-blocking drug with an extremely long recovery from use-dependent sodium channel block.Fórmula:C27H42N3O3Pureza:98%Cor e Forma:SolidPeso molecular:456.64Plm IV inhibitor-2
CAS:"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."Fórmula:C39H54N4O4Cor e Forma:SolidPeso molecular:642.875-cis Carbaprostacyclin
CAS:5-cis Carbaprostacyclin: a PGI2 stable analog; poor human platelet aggregation inhibitor (IC50: 2.8 μM); weakens rabbit artery relaxation (EC50: 104 μM).Fórmula:C21H34O4Cor e Forma:SolidPeso molecular:350.495(S),6(R)-DiHETE
CAS:5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47
