Outros inibidores
Esta categoria abrange uma ampla variedade de inibidores que não se encaixam nas classificações padrão, mas que ainda são essenciais para várias pesquisas bioquímicas e farmacológicas. Esses inibidores podem direcionar vias, enzimas e interações moleculares únicas ou menos estudadas, fornecendo ferramentas valiosas para áreas de pesquisa especializadas. Na CymitQuimica, oferecemos uma seleção diversificada de inibidores de alta qualidade que abrangem múltiplos alvos biológicos e disciplinas de pesquisa, permitindo que você explore novas vias terapêuticas e aprofunde sua compreensão de processos biológicos complexos.
Foram encontrados 36770 produtos de "Outros inibidores"
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SLC4101431
<p>SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.</p>Fórmula:C29H28ClN7OSCor e Forma:SolidPeso molecular:558.1MDL-100173
CAS:<p>MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.</p>Fórmula:C24H26N2O4SCor e Forma:SolidPeso molecular:438.54CJ-887
CAS:<p>CJ-887 is a STAT3 inhibitor.</p>Fórmula:C34H45N6O10PCor e Forma:SolidPeso molecular:728.7315(R)-Lipoxin A4
CAS:<p>Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.47Epiderstatin
CAS:<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Fórmula:C15H20N2O4Cor e Forma:SolidPeso molecular:292.33NB-216
CAS:NB-216 is a macrocyclic peptidic BACE-1 inhibitor.Fórmula:C35H45N3O4Cor e Forma:SolidPeso molecular:571.75SHR0687
CAS:<p>SHR0687: potent KOR agonist, selective, favorable PK, effective in rat pain model, minimal BBB penetration, less CNS side effects.</p>Fórmula:C39H60N8O5Cor e Forma:SolidPeso molecular:720.94Olanzapine/Samidorphan
CAS:Olanzapine/Samidorphan, a tablet blending olanzapine and samidorphan, targets schizophrenia and bipolar I, curbing weight gain.Fórmula:C38H46N6O4SCor e Forma:SolidPeso molecular:682.88Flurandrenolone Acetate
CAS:Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.Fórmula:C26H35FO7Cor e Forma:SolidPeso molecular:478.55SSM3 TFA
CAS:SSM3 TFA is a potent furin inhibitor, blocking furin-dependent cell surface processing of anthrax protective antigen-83 in vitro..Fórmula:C22H32N12O2Cor e Forma:SolidPeso molecular:496.57DS89002333
<p>DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.</p>Fórmula:C22H20ClF2N3O3Cor e Forma:SolidPeso molecular:447.86Prohibitin ligand 1
Compound 22i, a prohibitin ligand, protects the heart at nanomolar levels by inducing STAT3 phosphorylation.Fórmula:C20H22N2OCor e Forma:SolidPeso molecular:306.4AL-6556
CAS:<p>AL-6556 is a prostaglandin DP receptor agonist.</p>Fórmula:C20H33ClO5Cor e Forma:SolidPeso molecular:388.93Tandutinib (MLN518) HCl
Tandutinib antagonizes FLT3, PDGFR, and c-Kit with an IC50 of ~200 nM.Fórmula:C31H43ClN6O4Pureza:98%Cor e Forma:SolidPeso molecular:599.16NS2B/NS3-IN-4
CAS:<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Fórmula:C15H11NO4Cor e Forma:SolidPeso molecular:269.25CU-2010
CAS:<p>CU-2010 is a synthetic compound that reduces blood loss and aids recovery post-cardiac surgery.</p>Fórmula:C37H42N6O6SCor e Forma:SolidPeso molecular:698.83TRK-IN-19
<p>TRK-IN-19 (I-10) inhibits TRKA (1.1 nM IC50) & TRKAG595R (5.3 nM), promising for cancer research.</p>Fórmula:C22H26FN5O2Cor e Forma:SolidPeso molecular:411.47AMPK Activator SC4
CAS:<p>SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.</p>Fórmula:C26H18ClN3O4Cor e Forma:SolidPeso molecular:471.89KMH-233
CAS:<p>KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.</p>Fórmula:C32H25N7O5Cor e Forma:SolidPeso molecular:587.58Nepaprazole sodium
CAS:Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.Fórmula:C18H18N3NaO2SCor e Forma:SolidPeso molecular:363.41Ganciclovir monophosphonate
CAS:Ganciclovir monophosphate treats CMV, inhibiting replication in human/animal strains (IC50: 0.01μM).Fórmula:C10H16N5O6PCor e Forma:SolidPeso molecular:333.24ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Fórmula:C33H37NO4Cor e Forma:SolidPeso molecular:511.65PF-06815345 hydrochloride
CAS:<p>PF-06815345 HCl is an oral, potent PCSK9 inhibitor, IC50 13.4 μM, lowers PCSK9 in mice.</p>Fórmula:C27H30Cl2FN9O4Cor e Forma:SolidPeso molecular:634.49Aspochalasin M
CAS:<p>Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.</p>Fórmula:C24H35NO4Cor e Forma:SolidPeso molecular:401.54GRPR antagonist-2
<p>GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).</p>Fórmula:C28H32F3N5O4Cor e Forma:SolidPeso molecular:559.58MEIS-IN-1
CAS:<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Fórmula:C24H21F3N2O4Cor e Forma:SolidPeso molecular:458.43Griseolic acid C
CAS:Griseolic acid C (Dihydrodeoxygriseolic acid) is an antibiotic found in the Streptomyces griseoaurantiacus SANK43894 strain. This compound is a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17], with an IC50 of 0.12 μM (enzyme sourced from rat brain tissue).Fórmula:C14H15N5O7Cor e Forma:SolidPeso molecular:365.298Amrubicin HCl
CAS:Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.Fórmula:C25H25NO9Cor e Forma:SolidPeso molecular:483.47Lobaric acid
CAS:<p>Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.</p>Fórmula:C25H28O8Cor e Forma:SolidPeso molecular:456.48Salfredin C1
CAS:<p>Salfredin C1 is an inhibitor of aldose reductase.</p>Fórmula:C13H11NO6Cor e Forma:SolidPeso molecular:277.229trans-Doxercalciferol
CAS:<p>trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.</p>Fórmula:C28H44O2Pureza:98%Cor e Forma:SolidPeso molecular:412.65TSWV-IN-1
TSWV-IN-1 is an anti-TSWV drug with potential TSWV N.Fórmula:C26H31FO4S2Cor e Forma:SolidPeso molecular:490.65GNE-616
CAS:<p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>Fórmula:C24H23F4N5O3SPureza:98%Cor e Forma:SolidPeso molecular:537.53Theophylline EP impurity C
CAS:<p>Theophylline EP impurity C, an alkaloid with anti-bronchospasm activity, is employed to assess the purity and quality of compounds. This substance also holds potential clinical value in the management of asthma and chronic obstructive pulmonary disease (COPD).</p>Fórmula:C7H10N4O3Cor e Forma:SolidPeso molecular:198.18Propizepine
CAS:Propizepine is a tricyclic antidepressant compound.Fórmula:C17H20N4OCor e Forma:SolidPeso molecular:296.37Gypsetin
CAS:<p>Gypsetin inhibits the activity of acyl-CoA:cholesterol acyltransferase (ACAT), showing inhibitory effects on rat liver microsomal ACAT with an IC50 of 18 μM, and competes with oleoyl-CoA substrate, possessing a Ki value of 5.5 μM. Additionally, Gypsetin prevents the formation of cholesterol esters from oleic acid with an IC50 of 0.65 μM.</p>Fórmula:C32H36N4O4Cor e Forma:SolidPeso molecular:540.653SID 125240931
CAS:<p>SID 125240931 is a regulator of fluorine-activated proteins (FAPs). This compound disrupts the binding between fluoride and FAPs.</p>Fórmula:C19H24N4O3SCor e Forma:SolidPeso molecular:388.48G12Si-1
G12Si-1 selectively binds and inhibits K-Ras(G12S) to block oncogenic signaling and nucleotide exchange.Fórmula:C29H32ClN5O3Cor e Forma:SolidPeso molecular:534.055-Deoxygentamicin C1
CAS:<p>5-Deoxygentamicin C1 exhibits activity against both gram-positive and gram-negative bacteria.</p>Fórmula:C21H43N5O6Cor e Forma:SolidPeso molecular:461.60RIP1 kinase inhibitor 1
CAS:RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.Fórmula:C24H20ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:461.9Unoprostone
CAS:Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.Fórmula:C22H38O5Pureza:98%Cor e Forma:SolidPeso molecular:382.53Atiratecan
CAS:Atiratecan (TP300), a CH0793076-based camptothecin prodrug, combats BCRP+/- tumors; doesn't affect AChE.Fórmula:C31H34N6O6Pureza:98%Cor e Forma:SolidPeso molecular:586.64Thielavin B
CAS:Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.Fórmula:C31H34O10Cor e Forma:SolidPeso molecular:566.6Monamycin I
CAS:Monamycin I is an ester peptide antibiotic with activity against Gram-positive bacteria.Fórmula:C35H58ClN7O8Cor e Forma:SolidPeso molecular:740.33Napsagatran hydrate
CAS:Napsagatran hydrate is a novel and specific inhibitor of thrombin.Fórmula:C26H36N6O7SPureza:98%Cor e Forma:SolidPeso molecular:576.66TRPC4/5-IN-1
TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.Fórmula:C21H21N3OCor e Forma:SolidPeso molecular:331.41SAR107375
CAS:<p>SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].</p>Fórmula:C24H30ClN5O5S2Cor e Forma:SolidPeso molecular:568.11KFA1982
CAS:<p>KFA1982 is a novel and potent factor Xa inhibitor.</p>Fórmula:C28H34ClN3O9S2Cor e Forma:SolidPeso molecular:656.17Calpain Inhibitor-2
CAS:<p>Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.</p>Fórmula:C26H33N3O5SCor e Forma:SolidPeso molecular:499.62Neoenactin B1
CAS:Neoenactin B1 exhibits potent antifungal activity against yeasts and filamentous fungi.Fórmula:C20H38N2O5Cor e Forma:SolidPeso molecular:386.53TKL-IN-2
CAS:TKL-IN-2 (Compound 7m) is a TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. It exhibits excellent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus, while being safe for corn, wheat, soybean, and cotton. TKL-IN-2 is suitable for research in weed control in crop fields.Fórmula:C23H17ClF3N3OCor e Forma:SolidPeso molecular:443.85eIF4A3-IN-6
CAS:eIF4A3-IN-6 is a potent eIF4A inhibitor, potentially used for treating eIF4A-related diseases like cancer. (US20170145026A1)Fórmula:C26H25N3O5Cor e Forma:SolidPeso molecular:459.49Damavaricin D
CAS:Damavaricin D exhibits activity against Gram-positive bacteria, Gram-negative bacteria, and fungi.Fórmula:C38H49NO12Cor e Forma:SolidPeso molecular:711.795FTI 276 TFA
CAS:FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).Fórmula:C23H28F3N3O5S2Cor e Forma:SolidPeso molecular:547.61ABCA1 inducer 1
CAS:<p>ABCA1 inducer 1, a non-lipid inducer of ABCA1, enhances ABCA1 expression in E3/4FAD mice expressing human APOE 3/4, augments the lipidation of apolipoprotein (APOE), and reverses various Alzheimer's disease (AD) phenotypes without increasing triglycerides.</p>Fórmula:C24H24Cl2N2O7S2Cor e Forma:SolidPeso molecular:587.49Hypoglycemic agent 1
CAS:<p>Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.</p>Fórmula:C25H24FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:477.49Cicaprost
CAS:<p>Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.</p>Fórmula:C22H30O5Cor e Forma:SolidPeso molecular:374.47PNU-140457
CAS:PNU-140457 is a bio-active chemical.Fórmula:C14H14FN5O3Cor e Forma:SolidPeso molecular:319.29Bagremycin B
CAS:<p>Bagremycin B is produced by the bacterium Streptomyces strain Tu 4128. It exhibits weak activity against Gram-positive bacteria, Saccharomyces cerevisiae, and Candida albicans.</p>Fórmula:C17H15NO4Cor e Forma:SolidPeso molecular:297.305Hydroxyakalone
CAS:Hydroxyakalone is an inhibitor of the enzyme xanthine oxidase (XOD, EC 1.2.3.2) and has an IC50 of 4.6 μM for XOD.Fórmula:C5H5N5O2Cor e Forma:SolidPeso molecular:167.126TP3011
CAS:TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.Fórmula:C26H26N4O5Pureza:98%Cor e Forma:SolidPeso molecular:474.51ALK5-IN-82
CAS:<p>ALK5-IN-82 is a potent and selective inhibitor of activin receptor-like kinase 5 (ALK5), demonstrating an IC50 value of 9.1 nM. This compound effectively suppresses the expression of α-smooth muscle actin (α-SMA), collagen I, and the proteinases tissue inhibitor of metalloproteinase 1 (TIMP-1) and matrix metalloproteinase 13 (MMP-13) in human umbilical vein endothelial cells induced by transforming growth factor-β. ALK5-IN-82 shows potential for use in research related to cardiac fibrosis.</p>Fórmula:C22H19N7OSCor e Forma:SolidPeso molecular:429.50Dynemicin Q
CAS:<p>Dynemicin Q is an antibiotic that demonstrates potent activity against Gram-positive bacteria.</p>Fórmula:C28H19NO9Cor e Forma:SolidPeso molecular:513.45α-Prumycin hydrochloride
CAS:α-Prumycin hydrochloride is a carbohydrate antibiotic with antifungal properties and weak antibacterial activity.Fórmula:C8H19Cl2N3O4Cor e Forma:SolidPeso molecular:292.16Malioxamycin
CAS:<p>Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by suppressing peptidoglycan synthesis in the bacterial cell wall and promoting the formation of protoplasts.</p>Fórmula:C9H16N2O6Cor e Forma:SolidPeso molecular:248.233Monamycin H2
CAS:<p>Monamycin H2 is an ester peptide antibiotic that exhibits activity against Gram-positive bacteria.</p>Fórmula:C34H56ClN7O8Peso molecular:726.30De-N-methylpamamycin-593A
CAS:<p>De-N-methylpamamycin-593A is a 16-membered macrocyclic dilactone known for its ability to induce aerial mycelium formation.</p>Fórmula:C34H59NO7Peso molecular:593.84Calphostin I
CAS:Calphostins, from Cladosporium fungus, inhibit PKC. Notably, calphostin C is a potent biochemical tool.Fórmula:C44H38O15Cor e Forma:SolidPeso molecular:806.765,6-Dihydro-4-methoxy-2H-pyran-2-one
CAS:<p>5,6-Dihydro-4-methoxy-2H-pyran-2-one is produced by the Penicillium italicum strain MRC 1360.</p>Fórmula:C6H8O3Peso molecular:128.13Lucilactaene
CAS:<p>Lucilactaene exhibits potent antimalarial activity and functions as a P53-transfected tumor cell cycle inhibitor. It effectively halts the cell cycle progression of H1299/TSP53 cells at the G1 phase.</p>Fórmula:C22H27NO6Peso molecular:401.45Melanoxazal
CAS:<p>Melanoxazal is an inhibitor of melanin biosynthesis, effectively suppressing melanin formation in silkworm larva hemolymph with an IC50 of 30.1 μg/mL, and it also exhibits strong inhibitory effects on mushroom tyrosinase (IC50 of 4.2 μg/mL), while lacking antibacterial activity.</p>Fórmula:C8H9NO3Peso molecular:167.16Demycarosyl platenomycin
CAS:<p>Demycarosylplatenomycin (DM-PLM) is an antibiotic that exhibits mild activity against Gram-positive bacteria.</p>Fórmula:C31H51NO11Peso molecular:613.74VEGFR-2-IN-17
VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.Fórmula:C21H14ClN3O2Cor e Forma:SolidPeso molecular:375.81Hazimycin 6
CAS:Hazimycin 6 exhibits weak activity against gram-negative bacteria, yeast, and dermatophytes.Fórmula:C20H18N4O4Cor e Forma:SolidPeso molecular:378.381Pelagiomicin C
CAS:Pelagiomicin C exhibits activity against both Gram-positive and Gram-negative bacteria.Fórmula:C17H15N3O5Cor e Forma:SolidPeso molecular:341.3183-O-Demethyl-2'-N-glylfortimicin B
CAS:<p>3-O-Demethyl-2'-N-glylfortimicin B is a type of aminoglycoside antibiotic.</p>Fórmula:C16H33N5O6Cor e Forma:SolidPeso molecular:391.463GW311616 hydrochloride
CAS:<p>GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).</p>Fórmula:C19H32ClN3O4SPureza:98%Cor e Forma:SolidPeso molecular:433.99Fleephilone
CAS:<p>Fleephilone is a fungal metabolite isolated from Trichoderma harzianum. It acts as an HIV REV/RRE binding inhibitor, hindering the interaction between REV protein and RRE RNA with an IC50 of 7.6 μM.</p>Fórmula:C24H27NO7Cor e Forma:SolidPeso molecular:441.474Hypercalin B
CAS:<p>Hypercalin B is an antibacterial agent isolated from the hexane and chloroform extracts of Hypericum acmosepalum. It demonstrates activity against multidrug-resistant strains of Staphylococcus aureus, with a minimum inhibitory concentration (MIC) ranging from 0.5 to 128 mg/L.</p>Fórmula:C33H42O5Cor e Forma:SolidPeso molecular:518.684Hitachimycin
CAS:Hitachimycin is a macrolide antibiotic with properties that inhibit the growth of tumor cells and exhibit antiprotozoal activity.Fórmula:C29H35NO5Cor e Forma:SolidPeso molecular:477.59212(S)-HEPE
CAS:<p>12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.</p>Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45Mollisin
CAS:<p>Mollisin is a quinone antibiotic with antifungal properties.</p>Fórmula:C14H10Cl2O4Cor e Forma:SolidPeso molecular:313.133METTL3-IN-3
CAS:METTL3-IN-3 is a polyheterocyclic compound, acts as METTL3 inhibitor .Fórmula:C26H28BrFN6O2Cor e Forma:SolidPeso molecular:555.44Flavipucine
CAS:<p>Flavipucine (Flavipucin) is a glutarimide antibiotic found in the Aspergillus flavipes F-2090/7 strain. It exhibits antibacterial activity against Bacillus subtilis, possesses antiprotozoal properties, and demonstrates cytotoxic effects on various cancer cells.</p>Fórmula:C12H15NO4Cor e Forma:SolidPeso molecular:237.252Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Fórmula:C29H52INO2Cor e Forma:SolidPeso molecular:573.63PS-519
CAS:<p>PS-519 is a human tissue plasminogen activator and proteasome inhibitor.</p>Fórmula:C12H19NO4Cor e Forma:SolidPeso molecular:241.28FCE-24379
CAS:FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.Fórmula:C20H22N4O2Cor e Forma:SolidPeso molecular:350.41PIKfyve-IN-1
PIKfyve-IN-1: potent, cell-active inhibitor for PIKfyve research, IC50=6.9 nM.Fórmula:C20H21N5Cor e Forma:SolidPeso molecular:331.41PAD2-IN-1 hydrochloride
PAD2-IN-1 hydrochloride: potent, selective PAD2 inhibitor; 95x less on PAD4, 79x less on PAD3; benzimidazole derivative.Fórmula:C25H30ClFN6O3Cor e Forma:SolidPeso molecular:517HOE-288
CAS:HOE-288 is a converting enzyme (CE) inhibitor.Fórmula:C27H38N2O5Cor e Forma:SolidPeso molecular:470.60DN-F01
<p>DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.</p>Fórmula:C22H16N2O2Cor e Forma:SolidPeso molecular:340.37Methymycin
CAS:Methymycin is a macrolide antibiotic with activity against Gram-positive bacteria and some Gram-negative bacteria.Fórmula:C25H43NO7Cor e Forma:SolidPeso molecular:469.611GLS1 Inhibitor-5
<p>GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.</p>Cor e Forma:SolidAZ12971554
AZ12971554: Human thrombin inhibitor, Ki=0.3nM; APTT IC50=0.68µM; ECT IC50=0.16µM.Fórmula:C20H17ClFN7O3Cor e Forma:SolidPeso molecular:457.85Chitinovorin A
CAS:<p>Chitinovorin A is a β-lactam antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.</p>Fórmula:C26H41N9O11SCor e Forma:SolidPeso molecular:687.722Mycoversilin
CAS:<p>Mycoversilin is an antibiotic with inhibitory activity against dermatophytes and plant pathogenic fungi, but it does not exhibit activity against yeasts and bacteria. It strongly inhibits protein synthesis.</p>Fórmula:C18H16O8Cor e Forma:SolidPeso molecular:360.315NTPDase-IN-1
NTPDase-IN-1 selectively inhibits NTPDases 1, 2, 8 with IC50 of 0.05, 0.23, 0.54 μM. Non-competitive, K m 21 μM, used in cancer, immune, infection research.Fórmula:C18H25N3OS2Cor e Forma:SolidPeso molecular:363.54TLR7/8 agonist 7
CAS:<p>TLR7/8 agonist 7 activates immune cells, useful in ISAC synthesis and immunity research.</p>Fórmula:C26H37N7O2Cor e Forma:SolidPeso molecular:479.62RXR antagonist 1
RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.Fórmula:C28H33F3N2O3Cor e Forma:SolidPeso molecular:502.57GDC-6036-NH
CAS:<p>GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.</p>Fórmula:C26H30ClF4N7OPureza:99.84%Cor e Forma:SolidPeso molecular:568.01TIY-7
TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.Cor e Forma:SolidEkatetrone
CAS:<p>Ekatetrone displays activity against both Gram-positive and Gram-negative bacteria, with particularly strong inhibitory effects on Mycobacterium tuberculosis.</p>Fórmula:C19H13NO7Cor e Forma:SolidPeso molecular:367.309Nemotin
CAS:<p>Nemotin exhibits activity against Gram-positive bacteria, mycobacteria, and fungi, while its effectiveness against Gram-negative bacteria is present but relatively weaker.</p>Fórmula:C11H8O2Cor e Forma:SolidPeso molecular:172.18Dephostatin
CAS:<p>Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor isolated from Streptomyces spp., exhibiting activity within the micromolar range.</p>Fórmula:C7H8N2O3Cor e Forma:SolidPeso molecular:168.15Megovalicin A
CAS:<p>Megovalicin A is effective against Bacillus subtilis and Escherichia coli.</p>Fórmula:C35H63NO8Cor e Forma:SolidPeso molecular:625.88Echinocandin B nucleus
CAS:Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B decarboxylase. It serves as an intermediate in the semisynthetic production of antifungal agents.Fórmula:C34H51N7O15Cor e Forma:SolidPeso molecular:797.807Glidobactin B
CAS:Glidobactin B is an antitumor antibiotic. It is active against pathogenic fungi and yeasts and can prolong the survival time of mice inoculated with leukemia P388 cells.Fórmula:C29H46N4O6Cor e Forma:SolidPeso molecular:546.699GSK945237
CAS:<p>GSK945237 is a type IIA topoisomerase inhibitor, effective on Gram-positive and negative bacteria, with favorable pharmacokinetics and in vivo efficacy.</p>Fórmula:C24H26FN5O3Cor e Forma:SolidPeso molecular:451.49Tribenuron
CAS:<p>Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.</p>Fórmula:C14H15N5O6SCor e Forma:SolidPeso molecular:381.36PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Fórmula:C22H22O11Cor e Forma:SolidPeso molecular:462.4PCSK9-IN-17
CAS:<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Fórmula:C16H19N5OSCor e Forma:SolidPeso molecular:329.42CPX-351
CAS:<p>CPX-351 (Vyxeos) is a liposomal encapsulant of cytarabine and Zoerythromycin with potential antitumor activity.</p>Fórmula:C36H42N4O15Pureza:98.95% - 99.763%Cor e Forma:SolidPeso molecular:770.74GNE-203
CAS:<p>GNE-203 is a Met inhibitor.</p>Fórmula:C30H29Cl2F3N8O3Cor e Forma:SolidPeso molecular:677.50Epithienamycin F
CAS:Epithienamycin F is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacteria.Fórmula:C13H18N2O8S2Cor e Forma:SolidPeso molecular:394.421MB725
CAS:MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.Fórmula:C18H21IN4O2SCor e Forma:SolidPeso molecular:484.35BMS-824
CAS:<p>BMS-824: potent HCV NS5A inhibitor, IC50 ~5 nM, therapeutic index >10,000, specific to HCV.</p>Fórmula:C27H25F3N4O5Cor e Forma:SolidPeso molecular:542.51ZK824859 hydrochloride
ZK824859 hydrochloride: oral uPA inhibitor with IC50 of 79 nM (uPA), 1580 nM (tPA), 1330 nM (fibrin).Fórmula:C23H23ClF2N2O4Cor e Forma:SolidPeso molecular:464.89TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Fórmula:C24H27N5O2Cor e Forma:SolidPeso molecular:417.5SSTR4 agonist 4
CAS:SSTR4 agonist 4, potent in pain research, shows promise in rodent pain models, with potential for Alzheimer's due to hippocampus activity.Fórmula:C19H26N4OCor e Forma:SolidPeso molecular:326.44BRD-K25923209
CAS:BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.Fórmula:C29H36N4O3Cor e Forma:SolidPeso molecular:488.62PDE4-IN-6
PDE4-IN-6: Potent PDE4 inhibitor, IC50 - 0.125μM (B), 0.43μM (D), anti-inflammatory, for arthritis research.Fórmula:C25H20FNO5SCor e Forma:SolidPeso molecular:465.49Azonafide-PEABA
CAS:<p>Azonafide-PEABA is a drug moiety with cytotoxic [1].</p>Fórmula:C32H33N5O4Pureza:98%Cor e Forma:SolidPeso molecular:551.64MK-1220
CAS:MK-1220 is a novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.Fórmula:C40H53N5O9SCor e Forma:SolidPeso molecular:779.94LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Fórmula:C20H19FN6O3Cor e Forma:SolidPeso molecular:410.4CXCR4 probe 1
CAS:<p>CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.</p>Fórmula:C24H30FN5O4SCor e Forma:SolidPeso molecular:502.59MDK6465
CAS:MDK6465 (PCSK9-IN-8b), CAS#1900686-46-5, is a liver-targeted PCSK9 synthesis inhibitor.Fórmula:C27H29ClFN9O4Cor e Forma:SolidPeso molecular:598.03Cinnatriacetin A
CAS:<p>Cinnatriacetin A exhibits activity against Gram-positive bacteria.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.402MRS2279
CAS:Selective, high affinity competitive antagonist of the P2Y1 receptorFórmula:C13H18ClN5O8P2Pureza:98%Cor e Forma:SolidPeso molecular:469.71PTP1B-IN-17
PTP1B-IN-17, a benzimidazole derivative, inhibits PTP1B (Ki: 30.2 μM) and may help study type 2 diabetes.Fórmula:C26H19N3O4SCor e Forma:SolidPeso molecular:469.51UNC7467
CAS:<p>UNC7467, potent IP6K2/1/6 inhibitor (4.9/8.9/1320 nM); lowers inositol pyrophosphates, minimal impact on other inositol phosphates; for obesity research.</p>Fórmula:C20H13NO3Pureza:98.28% - 98.64%Cor e Forma:SoildPeso molecular:315.32NRX-2663
CAS:NRX-2663 boosts β-catenin binding to E3 ligase SCFβ-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).Fórmula:C20H13F3N2O5Cor e Forma:SolidPeso molecular:418.32Ro-51
CAS:dual P2X3 and P2X2/3 antagonistFórmula:C17H23IN4O4Pureza:98%Cor e Forma:SolidPeso molecular:474.29FTO-IN-5
CAS:<p>FTO-IN-5 is a potent, selective inhibitor targeting the fat mass obesity-associated protein (FTO).</p>Fórmula:C23H18Cl2N6O6Cor e Forma:SolidPeso molecular:545.33Exicorilant
CAS:Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.Fórmula:C26H23F4N7O3SPureza:98%Cor e Forma:SolidPeso molecular:589.56Albicidin
CAS:Albicidin is a DNA gyrase inhibitor produced by Xanthomonas albilineans.Fórmula:C44H38N6O12Cor e Forma:SolidPeso molecular:842.818CGC 11150
CAS:<p>CGC 11150 is a polyamine analogue inhibit tumor growth in vitro and in vivo.</p>Fórmula:C40H100Cl10N10Cor e Forma:SolidPeso molecular:1075.82Protease-Activated Receptor-1 antagonist 3
PAR-1 antagonist 3: potent (IC50: 7 nM), binds hERG K+ channels (IC50: 9 μM).Fórmula:C30H34N4O3Cor e Forma:SolidPeso molecular:498.62KDOAM-25 trihydrochloride (2230731-99-2 free base)
KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.Fórmula:C15H28Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:416.77Anticancer agent 17
Anticancer agent 17 was effective against HeLa cells (IC50: 0.19 μM) and A2780 cells (IC50: 0.09 μM).Fórmula:C27H34BrN3OCor e Forma:SolidPeso molecular:496.48OM-153
CAS:OM-153 blocks tankyrase 1 (IC50: 13 nM) and 2 (IC50: 2 nM), stifling WNT signaling and COLO 320DM cell growth.Fórmula:C28H24FN7O2Cor e Forma:SolidPeso molecular:509.53L-744832
CAS:<p>L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity.</p>Fórmula:C26H45N3O6S2Cor e Forma:SolidPeso molecular:559.78Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Fórmula:C30H30N6O4SCor e Forma:SolidPeso molecular:570.66VEGFR-2-IN-12
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 (IC50: 0.037 μM). VEGFR-2-IN-12 has anti-tumour effects.Fórmula:C22H24N6O3SCor e Forma:SolidPeso molecular:452.53Tubulosine
CAS:Tubulosine is an anticancer agent that inhibits cancer cell growth.Fórmula:C29H37N3O3Cor e Forma:SolidPeso molecular:475.62Sovesudil hydrochloride
<p>Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.</p>Fórmula:C23H23ClFN3O3Cor e Forma:SolidPeso molecular:443.9PAD-IN-2
CAS:<p>PAD-IN-2, potent PAD4 inhibitor, IC50 <1 μM; targets autoimmune/cancer disorders.</p>Fórmula:C27H28ClN5O2Cor e Forma:SolidPeso molecular:490RMI-18341
CAS:RMI-18341 is a Testosterone 5 alpha reductase inhibitor.Fórmula:C22H34N2O2Cor e Forma:SolidPeso molecular:358.52Anti-TSWV agent 1
<p>Anti-TSWV agent 1 is a highly effective inactivator (EC50:144 μg/mL) of tomato spotted wilt virus (TSWV).</p>Fórmula:C22H27ClN4OS3Cor e Forma:SolidPeso molecular:495.12Anticancer agent 79
<p>Anticancer agent 79 (3d) has potent activity against breast cancer, with cytotoxic effects on T47-D, IC50=13.64±0.26μM.</p>Fórmula:C20H12F3NO5Cor e Forma:SolidPeso molecular:403.31FTI-2628
CAS:<p>FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.</p>Fórmula:C31H34N4O3SCor e Forma:SolidPeso molecular:542.69P-gp modulator 1
CAS:P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulatorFórmula:C41H72N2O6Pureza:98%Cor e Forma:SolidPeso molecular:689.02ATUX-1215
CAS:<p>ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70,</p>Fórmula:C27H24F5NO4SCor e Forma:SolidPeso molecular:553.54SK&F 108361
CAS:<p>SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.</p>Fórmula:C24H48N6O6Cor e Forma:SolidPeso molecular:516.67Tilpisertib fosmecarbil
CAS:Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.Fórmula:C35H36ClN8O7PCor e Forma:SolidPeso molecular:747.142-Methylsorbinol
CAS:2-Methylsorbinol is a bioactive chemical.Fórmula:C12H11FN2O3Cor e Forma:SolidPeso molecular:250.23PD-1/PD-L1-IN-13
PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-Fórmula:C36H34ClF2N3O9Cor e Forma:SolidPeso molecular:726.12M-89 MLL inhibitor
CAS:M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.Fórmula:C37H47N5O4SCor e Forma:SolidPeso molecular:657.87TLN-232
CAS:<p>TLN-232, a synthetic heptapeptide, may inhibit cancer by targeting M2PK to disrupt tumor cell energy production.</p>Fórmula:C36H49N9O7S2Cor e Forma:SolidPeso molecular:783.9618-Deoxyherboxidiene
CAS:<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Fórmula:C25H42O5Cor e Forma:SolidPeso molecular:422.6Vindeburnol
CAS:<p>Vindeburnol is a cerebral vasodilator vincamine analog that bears neuroprotective properties.</p>Fórmula:C17H20N2OCor e Forma:SolidPeso molecular:268.35Tetrahydrouridine dihydrate
<p>THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.</p>Fórmula:C9H20N2O8Cor e Forma:SolidPeso molecular:284.26Heme Oxygenase-1-IN-2
<p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>Fórmula:C19H18ClN3OCor e Forma:SolidPeso molecular:339.82Plagiochilin A
CAS:<p>Plagiochilin A Inhibits Cytokinetic Abscission and Induces Cell Death</p>Fórmula:C15H14O7Cor e Forma:SolidPeso molecular:306.27BMS-961955
CAS:<p>BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase.</p>Fórmula:C37H43FN4O4SCor e Forma:SolidPeso molecular:658.83Ac-ATS010-KE
CAS:<p>Ac-ATS010-KE is a novel Selective, irreversible, and Rapid Cell-Permeable Inhibitor of Human Caspase-3.</p>Fórmula:C43H41F5N6O12SCor e Forma:SolidPeso molecular:960.88AS1940477
CAS:<p>AS1940477 selectively inhibits p38 MAPK α/β, blocks proinflammatory cytokines in cells, and has anti-inflammatory effects in rats.</p>Fórmula:C24H22FN5O2Cor e Forma:SolidPeso molecular:431.46Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Fórmula:C28H32BrN3O2Cor e Forma:SolidPeso molecular:522.48NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Fórmula:C14H9IN2O3SCor e Forma:SolidPeso molecular:412.2Mf 268
CAS:<p>Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.</p>Fórmula:C28H46N4O3Cor e Forma:SolidPeso molecular:486.69Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).Fórmula:C19H12BrNO5Cor e Forma:SolidPeso molecular:414.21AL 6598
CAS:AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.Fórmula:C23H39ClO5Cor e Forma:SolidPeso molecular:431.01Ascofuranone
CAS:<p>Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH</p>Fórmula:C23H29ClO5Cor e Forma:SolidPeso molecular:420.93Dehatrine
CAS:Dehatrine: alkaloid from Beilschmiedia madang, inhibits Plasmodium falciparum K1 growth.Fórmula:C37H38N2O6Cor e Forma:SolidPeso molecular:606.71AMG-222 tosylate
CAS:<p>AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.</p>Fórmula:C39H47N9O6SCor e Forma:SolidPeso molecular:769.91GW-597901 cinnamate
CAS:<p>GW-597901 cinnamate is a long-acting beta(2)-agonist.</p>Fórmula:C34H46N2O8SCor e Forma:SolidPeso molecular:642.80Topoisomerase I inhibitor 8
CAS:<p>Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.</p>Fórmula:C24H21FN2O4Cor e Forma:SolidPeso molecular:420.43Cilengitide hydrochloride
CAS:Cilengitide hydrochloride is a salt that may combat cancer by blocking specific integrins, disrupting cell interactions and angiogenesis.Fórmula:C27H41ClN8O7Cor e Forma:SolidPeso molecular:625.12AVE-1330A sodium
CAS:<p>AVE-1330A sodium is a beta-Lactamase inhibitor.</p>Fórmula:C7H10N3NaO6SCor e Forma:SolidPeso molecular:287.23Gepotidacin hydrochloride
CAS:<p>Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.</p>Fórmula:C24H29ClN6O3Cor e Forma:SolidPeso molecular:484.98DGY-08-097
CAS:<p>DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.</p>Fórmula:C60H76N10O14Cor e Forma:SolidPeso molecular:1161.3T-3861174
CAS:<p>T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.</p>Fórmula:C26H25FN6O2Cor e Forma:SolidPeso molecular:472.51SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Fórmula:C35H38N6O3Cor e Forma:SolidPeso molecular:590.71Lp-PLA2-IN-6
CAS:Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Fórmula:C25H21F5N4O3Cor e Forma:SolidPeso molecular:520.45LAF-153
CAS:LAF-153 is a reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor.Fórmula:C18H32N2O7Cor e Forma:SolidPeso molecular:388.46AS2575959
CAS:<p>AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.</p>Fórmula:C32H35NaO7Cor e Forma:SolidPeso molecular:554.6148TP-030-1
CAS:TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.Fórmula:C23H22N4O3Cor e Forma:SolidPeso molecular:402.45D-473
CAS:<p>D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.</p>Fórmula:C26H27F2NO3Cor e Forma:SolidPeso molecular:439.499-Hydroxycrisamicin
CAS:9-Hydroxycrisamicin exhibits moderate activity against Gram-positive bacteria with a minimum inhibitory concentration (MIC) ranging from 6.25 to 25 μg/mL. Additionally, 9-Hydroxycrisamicin demonstrates significant growth inhibition towards various human tumor cell lines.Fórmula:C32H22O13Cor e Forma:SolidPeso molecular:614.51PD-149163
CAS:<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Fórmula:C42H71N9O6Cor e Forma:SolidPeso molecular:798.07AL-GDa62
<p>AL-GDa62, a gastric cancer treatment lead, has EC50 of 3.2 μM (MCF10A-WT) and 2 μM (MCF10A-CDH1 -/-).</p>Fórmula:C24H28FN3OCor e Forma:SolidPeso molecular:393.5STA 2
CAS:STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium.Fórmula:C21H34O3SCor e Forma:SolidPeso molecular:366.56Everafenib
Everafenib: potent BRAF inhibitor, crosses blood-brain barrier, hinders MAPK, effective on V600EBRAF cells, outperforms other drugs in trials.Fórmula:C20H23ClFN5O2S2Cor e Forma:SolidPeso molecular:484.01Mycinamicin Ⅵ
CAS:<p>Mycinamicin VI is a macrolide antibiotic with antibacterial activity against Gram-positive bacteria.</p>Fórmula:C35H57NO11Cor e Forma:SolidPeso molecular:667.83FTO-IN-6
CAS:FTO-IN-6 is a selective inhibitor of fat mass and obesity associated protein (FTO).Fórmula:C14H12N4O6Cor e Forma:SolidPeso molecular:332.27Antitumor agent-187
CAS:Antitumor agent-187 (compound I) is an isoflavone derivative with antitumor activity. It exhibits IC50 values of 5.23 μM and 2.63 μM against A2780 and SKOV3 cell lines, respectively.Fórmula:C24H26N2O7Cor e Forma:SolidPeso molecular:454.476-Aminopyridine-3-thioamide
CAS:6-Aminopyridine-3-thioamide is a compound noted for its anticancer properties, capable of inhibiting the activity of specific enzymes that affect cell proliferation and survival. Furthermore, it has been studied for its potential to mitigate neurodegenerative diseases, exhibiting capabilities to enhance neural functions. The structural characteristics of 6-Aminopyridine-3-thioamide render it a significant bioactive molecule in compound development.Fórmula:C6H7N3SCor e Forma:SolidPeso molecular:153.215(S),6(R)-DiHETE
CAS:5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47MTSES sodium
CAS:<p>MTSES sodium (Sodium (2-Sulfonatoethyl)methanethiosulfonate) is a negatively charged, membrane-impermeable methanethiosulfonate (MTS). This MTS compound can react with thiol groups to form mixed disulfides, frequently utilized in studying cysteine residues on proteins.</p>Fórmula:C3H7NaO5S3Cor e Forma:SolidPeso molecular:242.275-Fluoroorotic acid monohydrate
CAS:5-Fluoroorotic acid (monohydrate) (5-Fluorouracil-6-carboxylic acid Mono(hydrate); 5-FOA) is employed to detect the expression of the URA3 gene in yeast molecular genetic constructs. Yeast possessing an active URA3 gene (which encodes orotidine-5'-monophosphate decarboxylase) convert 5-FOA into 5-fluorodeoxyuridine, a substance toxic to cells. Yeast strains with mutations in the URA3 gene that confer resistance can grow in the presence of 5-FOA if uracil is added to the medium.Fórmula:C5H5FN2O5Cor e Forma:SolidPeso molecular:192.10
