Outros inibidores

<p>The compound cis-3-Indoleacrylic acid acts as a nematicidal agent and can be isolated from Streptomyces youssoufiensis YMF3.862. It functions as a V-ATPase inhibitor, reducing both the expression and enzymatic activity of V-ATPase. Additionally, cis-3-Indoleacrylic acid causes swelling in Meloidogyne incognita larvae and notable cracking on the cuticle surface [LC50: 16.31 μg/mL]. It also inhibits the accumulation of H+ within nematodes.</p>

<p>M+B 5124 is a bioactive chemical.</p>

<p>(S)-ART0380 is an isomer of ART0380, a potent and selective ATR kinase inhibitor with anti-tumor activity.</p>

<p>Compound 0080-0061 is a useful organic compound for research related to life sciences and the catalog number is T131690.</p>

<p>Loxosceles Pilosa Venom, sourced from the same spider, contains proteins, glycoproteins, peptides, and enzymes like sphingomyelinase D causing necrosis.</p>

<p>Senecivernine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T126524.</p>

<p>Compound N037-0028 is a useful organic compound for research related to life sciences and the catalog number is T131290.</p>

<p>DL8F11 is a biochemical.</p>

<p>XE 820 is a biochemical.</p>

<p>AI 3-27211 is an insecticide.</p>

<p>Deoxyadenosine diphosphate sodium is a diphosphate nucleoside featuring deoxyadenosine as its nucleoside component. It plays a role in the synthesis and repair of DNA. Deoxyadenosine diphosphate sodium acts as an inhibitor of polynucleotide phosphorylase, thereby interfering with the polymerization of ADP and CDP.</p>

<p>Sporidesmolide II is a cyclic depsipeptide that was initially isolated from P. chartarum.</p>

<p>Relacidine B is an innovative non-ribosomal lipopeptide antibiotic that demonstrates promising activity against Gram-negative pathogens.</p>

<p>Synucleozid-2.0 is an innovative compound under investigation for neurodegenerative disease research, potentially acting by modulating neurotransmitters and cellular signaling pathways.</p>

<p>(S)-C12-200, the (S)-isomer of C12-200, is an ionizable cationic lipid and an auxiliary lipid. It is utilized in the formulation of lipid nanoparticles for mRNA delivery.</p>

<p>1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triglyceride composed of Stearic acid at the sn-1 position, Linoleic acid at the sn-2 position, and Oleic acid at the sn-3 position.</p>

<p>Eniclobrate (Sgd 33374) is a diphenylmethane derivative known for its lipid-lowering effects.</p>

<p>Gramicidin S 2HCl, is an antibiotic. At concentrations of 40-80 μg/mL, GS can reduce planktonic cell numbers within 20-40 minutes. For established biofilms, it effectively kills cells at concentrations of 100-200 μg/mL without regrowth. This anti-biofilm effect results from peptide transmembrane transport and complexation with intracellular nucleotides (including the alarmone ppGpp). GS demonstrates wide-ranging activity against biofilm-forming, drug-resistant infections caused by E. faecalis, proving its efficacy in endodontic treatment. The successful treatment of persistent infections in two volunteer cases further confirms GS's potent therapeutic performance. These studies indicate that GS can be applied in certifying compounds used in endodontics.</p>

<p>1,3-Dieicosatrienoin is a diacylglycerol that has 11(Z),14(Z),17(Z)-eicosatrienoic acid at the sn-1 and sn-3 positions.</p>

<p>S-palm P0(180–199) (TFA) is a peptide that enhances MHC II-restricted responses. It is utilized to develop models of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and chronic experimental autoimmune neuritis (c-EAN). S-palm P0(180–199) (TFA) is also studied in the context of autoimmune-mediated neuritis.</p>

<p>VICENISTATIN is a novel compound capable of inducing the vesiculation of early endosomes. It promotes the formation of vesicle-like structures by activating the Rab5-PAS pathway and enhancing membrane fluidity. Additionally, VICENISTATIN functions as an antitumor antibiotic, demonstrating antitumor activity against human colon cancer Co-3 in xenograft models.</p>

<p>Dioleoyl phosphatidylserine is a lipid under investigation, primarily used to study the assembly and long-term stability of solid-supported lipid bilayers formed from artificial and natural lipid mixtures.</p>

<p>Aeruginascin is an indole derivative and a tryptamine, extractable from [Inocybe aeruginascens Babos]. Aeruginascin may induce euphoria in states of psychosis accompanied by hallucinations.</p>

<p>OA2 lipid is an ionizable lipid that can form single-component lipid nanoparticles (LNPs) for the delivery of RNA.</p>

<p>4,4'-Thiodi(3-methyl-6-tert-butylphenol) is a biaoctive chemical.</p>

<p>YM 471 is a non-peptide arginine vasopressin (AVP) V1A and V2 receptor antagonist with oral activity.</p>

<p>Cryptostrobin is a useful organic compound for research related to life sciences and the catalog number is T131492.</p>

<p>J-1924 is a bioactive chemical.</p>

<p>Gummosin is a natural product that can be used as a reference standard. The CAS number of Gummosin is 51819-92-2.</p>

<p>Compound N064-0048 is a useful organic compound for research related to life sciences and the catalog number is T131201.</p>

<p>Coromandaline is a useful organic compound for research related to life sciences and the catalog number is T124403.</p>

<p>Cartilaginomarginadin is a biochemical.</p>

<p>Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.</p>

<p>3,5-Dibromo-4-methoxybenzoic acid was isolated from the Malagasy sponge Amphimedon sp.</p>

<p>Atlantinone A is a natural product that can be used as a reference standard. The CAS number of Atlantinone A is 1229025-12-0.</p>

<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>

<p>UT-11: potent, brain-permeable mPGES-1 inhibitor. IC50: 0.10μM (human SK-N-AS), 2.00μM (murine BV2). Stops PGE2 production.</p>

<p>GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.</p>

<p>Dagapamil is a calcium-channel blocker.</p>

<p>BOP-JF646: dual α9β1/α4β1 integrin inhibitor, fluorescent upon binding, no-wash, for live cell tracking. Ex/Em = 655/672 nm.</p>

<p>Isoabsouline is a useful organic compound for research related to life sciences and the catalog number is T126378.</p>

<p>Parishin G is a useful organic compound for research related to life sciences and the catalog number is T123869.</p>

<p>Penicinoline, an alkaloid from Penicillium, has antimalarial, insecticidal, and anticancer properties, effective against P. falciparum and A. gossypii.</p>

<p>Cholest-5-en-3-ol is a useful organic compound for research related to life sciences and the catalog number is T131630.</p>

<p>Rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.</p>

<p>3-methoxythio Benzamide, a synthetic pharma intermediate, is a potent liver toxin.</p>

<p>TFM: piscicide, lethal to sea lampreys &amp; small sturgeon, not most fish; impairs energy production in lamprey/trout liver. Used against larval lampreys.</p>

<p>PF-1543 is a bio-active chemical.</p>

<p>Glucobrassicin is a glucosinolate (GSL) that can be isolated from wild carrot (Raphanus raphanistrum L.). It is utilized in research on biofumigation or allelopathic plants for weed management.</p>

<p>Glucagon significantly impacts protein and amino acid metabolism.</p>