Outros inibidores

1-(Piperidin-4-yl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one is a useful organic compound for research related to life sciences and the catalog number is T66378.

<p>Benzyl (4-bromo-3-fluorophenyl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T66461 and the CAS number is 510729-01-8.</p>

<p>Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) is a useful organic compound for research related to life sciences. The catalog number is T66567 and the CAS number is 325146-81-4.</p>

7-TMCA is a useful organic compound for research related to life sciences. The catalog number is T65878 and the CAS number is 24209-38-9.

Enrofloxacin hydrochloride is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.

Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.

3-[2-(Trifluoromethyl)phenyl]propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65989 and the CAS number is 94022-99-8.

7-Amino-2H-chromen-2-one is a useful organic compound for research related to life sciences and the catalog number is T64948.

BnO-PEG4-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

4-Perhydroazepinone hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66790 and the CAS number is 50492-22-3.

<p>22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22(S)-hydroxy Cholesterol also reduces fatty acid synthase (FAS) reporter activity through an LXR response element in the promoter region in COS-1 cells transfected with RXRα and LXRα and decreases the expression of MCP-1 and CCR2 in a mouse model of chronic ethanol consumption.[1] [2] Dietary supplementation of 22(S)-hydroxy cholesterol (30 mg/kg per day) leads to less body weight gain and lower liver triacylglycerol levels in rats when fed either a regular chow or high-fat diet as well as prevents an increase in plasma triacylglycerol levels resulting from a high-fat diet.[3]</p>

<p>1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethanone is a useful organic compound for research related to life sciences. The catalog number is T66913 and the CAS number is 221615-75-4.</p>

<p>Water-18O is a useful organic compound for research related to life sciences and the catalog number is T64656.</p>

<p>HT-2 Toxin, a deacetylated metabolite of T-2 toxin, impairs protein synthesis and hinders cell proliferation in plants.</p>

<p>HSP70 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.</p>

<p>Bikunin/AMBP Protein, Human, Recombinant (aa 1-203, His) is expressed in HEK293 mammalian cells with His tag.</p>

<p>Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta).</p>

Intermediates and building blocks - phosphorous compounds; nucleophile

<p>BCL-W Protein, Human, Recombinant (His) is expressed in E.</p>

<p>LPL Protein, Chinese hamster, Recombinant (His) is expressed in E.</p>

<p>Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and</p>

<p>Heterocyclic compounds-pyridine,</p>

<p>S100A8 &amp; S100A9 Heterodimer Protein, Human, Recombinant (Flag &amp; His) is expressed in Baculovirus insect cells with Flag and His tag.</p>

<p>R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes.</p>

<p>CF502 (STING agonist-23) is a non-nucleotide that activates STING pathway, boosts immune responses, and shows activity against SARS-CoV.</p>

<p>Valiloxibic acid is a prodrug for GHB, a natural psychoactive neurotransmitter and weak GABAB agonist.</p>

<p>Alpha-Synuclein Protein, Human, Recombinant is expressed in E.</p>

<p>CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>

<p>Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>

<p>Hantaan virus HTNV (strain 84FLi) Nucleocapsid/NP Protein (His) is expressed in Baculovirus insect cells with His tag.</p>

<p>CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>

<p>Ammonium Glycyrrhizinate (Glycyram) inhibits the cytopathology and growth of several unrelated DNA/RNA viruses.</p>

<p>7-Methoxy-1-tetralone may have insecticidal activity.</p>

<p>MTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.</p>

<p>10Z-Nonadecenoic acid is a long-chain fatty acid with anti-tumor activity.</p>

<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>

<p>Elamipretide (SS-31, MTP-131, Bendavia) is a mitochondria-focused peptide that curbs toxic ROS and stabilizes cardiolipin.</p>

<p>Dimethylamine hydrochloride, found in urine, comes from food compound TMAO and NO synthesis inhibitor ADMA, processed by DDAH enzyme.</p>

<p>NBQX (FG9202), an AMPA/kainate receptor blocker, counters glutamate toxicity; water-soluble as disodium salt, has anticonvulsant properties.</p>

<p>Tropinone used as an intermediate in the synthesis of atropine sulfate, and is a decane alkaloid.</p>

<p>Elamipretide 2TFA (RX-31 2TFA) is a novel mitochondrion-targeted antioxidant.</p>

<p>α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation.</p>

Decyl-TPP bromide ((1-Decyl)triphenylphosphonium bromide) may be used as an intermediate for chemical synthesis and an inactive control or as a reference to

<p>Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.</p>

<p>4-Methoxycoumarine has antitumour effects.</p>

<p>Danoprevir sodium is an NS3/4A protease inhibitor used in the treatment of Hepatitis C</p>

<p>Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.</p>

<p>4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used as a flavoring agent, preservative and antioxidant in the food industry.</p>

<p>FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>

<p>SLC1A2 Protein, Mouse, Recombinant (GST) is expressed in E. coli. The accession number is P43006.</p>