Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1550 produtos de "Sinalização Citoesquelética"
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Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Pureza:>95%Cor e Forma:LiquidCK-666
CAS:CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.
Fórmula:C18H17FN2OPureza:99.93%Cor e Forma:SolidPeso molecular:296.34Meclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Fórmula:C14H10Cl2NNaO2Pureza:98% - 98.96%Cor e Forma:SolidPeso molecular:318.14Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Fórmula:C18H24ClN3O7Pureza:99.44% - 99.98%Cor e Forma:SolidPeso molecular:429.85Akt3 degrader 1
CAS:Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Fórmula:C53H72N8O4Pureza:98.12% - 99.02%Cor e Forma:SolidPeso molecular:885.19BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Fórmula:C20H20O7Pureza:96.57%Cor e Forma:SolidPeso molecular:372.37Ref: TM-T14694
1mg79,00€5mg152,00€10mg215,00€25mg351,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)167,00€(+)-Blebbistatin
CAS:(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.
Fórmula:C18H16N2O2Pureza:99.88%Cor e Forma:SolidPeso molecular:292.33Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Pureza:>95%Cor e Forma:Liquid7-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Fórmula:C10H12N2O5SPureza:91.05%Cor e Forma:White Solid PowderPeso molecular:272.28Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Fórmula:C46H62N4O11Pureza:98.87% - 99.7%Cor e Forma:Red-Violet Crystalline PowderPeso molecular:847Nilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.
Fórmula:C28H22F3N7OPureza:99.89% - >99.99%Cor e Forma:Off-White SolidPeso molecular:529.52IPI-493
CAS:IPI-493 is a bioactive chemical.Fórmula:C28H39N3O8Pureza:>99.99%Cor e Forma:SolidPeso molecular:545.62Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Fórmula:C17H31N7O10Pureza:98.14%Cor e Forma:SolidPeso molecular:493.47Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Cor e Forma:SolidPeso molecular:537.63Ref: TM-T16130
2mg37,00€5mg57,00€10mg92,00€25mg158,00€50mg269,00€100mg405,00€200mg568,00€1mL*10mM (DMSO)67,00€Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Cor e Forma:LiquidPeso molecular:145.79 kDaBepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Pureza:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Cor e Forma:LiquidAdropin (34-76) (human, mouse, rat)
CAS:Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Fórmula:C190H293N55O68S2Pureza:94.23% - 99.95%Cor e Forma:SolidPeso molecular:4499.82Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:506.03Donanemab
CAS:Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Pureza:95%Cor e Forma:LiquidPeso molecular:145.36 kDaBisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Fórmula:C26H26N4O4Pureza:99.27%Cor e Forma:SolidPeso molecular:458.51Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Fórmula:C17H20ClNOPureza:99.32% - 99.85%Cor e Forma:SolidPeso molecular:289.8LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Cor e Forma:SolidPeso molecular:502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Fórmula:C17H18N4O2SPureza:99.49%Cor e Forma:SoildPeso molecular:342.42Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Fórmula:C26H18ClN3O2Pureza:98.40%Cor e Forma:SolidPeso molecular:439.89Vedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Pureza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Cor e Forma:LiquidPeso molecular:146.80 kDaAKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.
Fórmula:C30H29F3N6OPureza:98.3%Cor e Forma:SoildPeso molecular:546.59Ref: TM-T80676
1mg94,00€2mg136,00€5mg224,00€10mg328,00€25mg505,00€50mg677,00€100mg929,00€200mg1.225,00€N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:Off-White To Pale-Yellow SolidPeso molecular:479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Fórmula:C16H13ClO4SPureza:98.85% - 98.96%Cor e Forma:SolidPeso molecular:336.79Ref: TM-T13862
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg177,00€50mg295,00€100mg477,00€200mg677,00€1mL*10mM (DMSO)100,00€CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Fórmula:C33H34N7Na2O7PPureza:98.87%Cor e Forma:SolidPeso molecular:717.63NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Fórmula:C35H39F3N8O3Pureza:99.84%Cor e Forma:SolidPeso molecular:676.73CC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Fórmula:C22H20ClN5O3SPureza:99.59%Cor e Forma:SolidPeso molecular:469.94TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Fórmula:C24H24N4O3Pureza:99.4%Cor e Forma:SoildPeso molecular:416.47Ref: TM-T77660
1mg39,00€2mg50,00€5mg82,00€10mg120,00€25mg236,00€50mg353,00€100mg517,00€500mg1.099,00€Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Fórmula:C24H30F2O6Pureza:99.29% - 99.82%Cor e Forma:Crystals From Acetone & Hexane SolidPeso molecular:452.49Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Pureza:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.73kDaFluorofenidone
CAS:Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.
Fórmula:C12H10FNOPureza:99.85%Cor e Forma:SolidPeso molecular:203.21Talquetamab
CAS:Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Cor e Forma:LiquidPeso molecular:144.59 kDaVeltuzumab
CAS:Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.33 kDaTidutamab
CAS:Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).Pureza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Cor e Forma:LiquidTubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Fórmula:C20H14ClNO2SPureza:99.05%Cor e Forma:SolidPeso molecular:367.85Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Pureza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidSGC-AAK1-1
CAS:SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
Fórmula:C21H25N5O3SPureza:99.68%Cor e Forma:SolidPeso molecular:427.52GNE 2861
CAS:GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Fórmula:C22H26N6O2Pureza:97.03%Cor e Forma:SolidPeso molecular:406.48Ref: TM-T16429
1mg43,00€2mg55,00€5mg87,00€10mg131,00€25mg259,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)92,00€Delcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Fórmula:C120H199N45O34S2Pureza:99.96%Cor e Forma:SolidPeso molecular:2880.28Ref: TM-T11740
1mg202,00€5mg512,00€10mg740,00€25mg1.121,00€50mg1.539,00€100mg2.072,00€1mL*10mM (DMSO)1.691,00€ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Fórmula:C15H18Cl2N2O2SPureza:99.69%Cor e Forma:Crystalline SolidPeso molecular:361.29Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Fórmula:C14H11NO4Pureza:99.03% - 99.96%Cor e Forma:SolidPeso molecular:257.24Ref: TM-T10860
2mg47,00€5mg70,00€10mg107,00€25mg216,00€50mg350,00€100mg542,00€200mg778,00€500mg1.169,00€1mL*10mM (DMSO)70,00€2,3-Butanedione 2-Monoxime
CAS:2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.Fórmula:C4H7NO2Pureza:98.62%Cor e Forma:Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:101.1Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:144.22 kDaMitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Cor e Forma:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Lyn-IN-1
CAS:Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFórmula:C30H31F3N8OPureza:97% - 98.02%Cor e Forma:SolidPeso molecular:576.62Ref: TM-T11916
1mg40,00€2mg52,00€5mg84,00€10mg124,00€25mg250,00€50mg393,00€100mg560,00€200mg812,00€1mL*10mM (DMSO)97,00€Ethoxyquin
CAS:Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Fórmula:C14H19NOPureza:97.15% - 98.73%Cor e Forma:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Peso molecular:217.31BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Fórmula:C24H30N8OPureza:99.37%Cor e Forma:SolidPeso molecular:446.55Xentuzumab
CAS:Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Pureza:95.21% - >95.0% (SDS-PAGE); >95.0% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:143.7 kDaElarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Fórmula:C26H34F6N4O8Pureza:99.08%Cor e Forma:SoildPeso molecular:644.56AC 7739
CAS:AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.
Fórmula:C18H22ClNO4Pureza:99.38% - 99.55%Cor e Forma:SoildPeso molecular:351.83PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Pureza:95.42%Cor e Forma:SoildTadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Pureza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:47.59 kDaA-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.
Fórmula:C12H14Cl2N2O2SPureza:99.32%Cor e Forma:SolidPeso molecular:321.22Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45ADH-1 trifluoroacetate
CAS:ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Fórmula:C24H35F3N8O8S2Pureza:90.08% - 99.98%Cor e Forma:SolidPeso molecular:684.71Ref: TM-T1608
2mg42,00€5mg62,00€10mg89,00€25mg167,00€50mg227,00€100mg339,00€200mg482,00€1mL*10mM (DMSO)89,00€NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Fórmula:C23H25ClF3N5OPureza:99.35%Cor e Forma:SolidPeso molecular:479.93Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFórmula:C17H18ClN3OPureza:98.29% - 99.77%Cor e Forma:SolidPeso molecular:315.8Ref: TM-T13298
5mg50,00€10mg78,00€25mg145,00€50mg210,00€100mg300,00€200mg434,00€1mL*10mM (DMSO)56,00€Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:589.71RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Fórmula:C18H17F3N4O2SPureza:99.09%Cor e Forma:SolidPeso molecular:410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Cor e Forma:LiquidPeso molecular:146.14 kDaAbciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:95.18 kDaIMAB027
CAS:Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.
Pureza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Cor e Forma:LiquidATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Fórmula:C25H39N9O10SPureza:98.27%Cor e Forma:SoildPeso molecular:657.7Ref: TM-T10398L
1mg201,00€5mg497,00€10mg701,00€25mg1.094,00€50mg1.508,00€100mg1.931,00€200mg2.637,00€CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Fórmula:C24H21F3N6OPureza:99.01% - 99.04%Cor e Forma:SolidPeso molecular:466.46Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01Danicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Fórmula:C16H20F3N5O4SPureza:99.38%Cor e Forma:SolidPeso molecular:435.42Ref: TM-T15050
1mg136,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€1mL*10mM (DMSO)303,00€Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Pureza:> 95% - >95.0% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:145.3 kDaATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Cor e Forma:SolidPeso molecular:711.67Glofitamab
CAS:Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.
Pureza:SDS-PAGE:98.2%;SEC-HPLC:98.0%Cor e Forma:LiquidPeso molecular:170.37 kDaAS1949490
CAS:AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Fórmula:C20H18ClNO2SPureza:99.94%Cor e Forma:SolidPeso molecular:371.88Ref: TM-T14327
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg236,00€50mg380,00€100mg555,00€1mL*10mM (DMSO)93,00€Mosunetuzumab
CAS:Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.Pureza:SDS-PAGE:94.4%;SEC-HPLC:96.1%Cor e Forma:LiquidPeso molecular:146.27 kDaCibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Cor e Forma:LiquidPeso molecular:191.1 kDaForalumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Cor e Forma:LiquidN-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Fórmula:C25H28ClNOPureza:99.15%Cor e Forma:SolidPeso molecular:393.95Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFórmula:C19H24F3N5O6Pureza:97.21% - 98.72%Cor e Forma:SolidPeso molecular:475.42Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidLarazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Fórmula:C34H59N9O12Pureza:95.53% - 99.425%Cor e Forma:SolidPeso molecular:785.89Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Fórmula:C16H11N3Pureza:99.91%Cor e Forma:SolidPeso molecular:245.28Ref: TM-T12359
5mg46,00€10mg58,00€25mg92,00€50mg160,00€100mg236,00€200mg353,00€500mg580,00€1mL*10mM (DMSO)49,00€Pamidronate Disodium
CAS:Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Fórmula:C3H9NNa2O7P2Pureza:99.86% - 99.93%Cor e Forma:White CrystalsPeso molecular:279.03Darifenacin hydrobromide
CAS:Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Fórmula:C28H31BrN2O2Pureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:505.45Spiperone
CAS:Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Fórmula:C23H26FN3O2Pureza:99.34% - 99.91%Cor e Forma:SolidPeso molecular:395.47MS98
CAS:MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.
Fórmula:C58H81ClN10O7SCor e Forma:SolidPeso molecular:1097.86JG-258
CAS:JG-258 is an inactive negative control for Hsp70 inhibitors [1] .Fórmula:C20H22ClN3OS3Cor e Forma:SolidPeso molecular:452.06FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Cor e Forma:LiquidSNIPER(ABL)-015
SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5Fórmula:C58H70F3N9O9Pureza:98%Cor e Forma:SolidPeso molecular:1094.23Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Fórmula:C16H13ClN6SCor e Forma:SolidPeso molecular:356.83Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSNIPER(ABL)-058
CAS:SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL proteinFórmula:C62H75N11O9SPureza:98%Cor e Forma:SolidPeso molecular:1150.39Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCor e Forma:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarMyosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.
Fórmula:C29H26N6O3SPureza:98.64% - 98.64%Cor e Forma:SolidPeso molecular:538.62Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Fórmula:C21H29N5O6Pureza:99.57%Cor e Forma:SolidPeso molecular:447.48Abl Cytosolic Substrate
CAS:Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).Fórmula:C64H101N15O16Pureza:98%Cor e Forma:SolidPeso molecular:1336.586BrCaQ-C10-TPP
6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.Fórmula:C45H47Br2N2O3PCor e Forma:SolidPeso molecular:854.65Eudebeiolide B
CAS:Eudebeiolide B, isolated from Salvia plebeia R.Fórmula:C15H18O4Pureza:98%Cor e Forma:SolidPeso molecular:262.3DSPE-PEG2000-cRGD
DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.Cor e Forma:Odour SolidPDS-0330
CAS:PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.Fórmula:C25H17N3O2SPureza:98.81%Cor e Forma:SoildPeso molecular:423.49
